Natural products have played and continue to play an invaluable role in the treatment of various diseases and in drug discovery processes. It has remained a source of new compounds with diversified structural arrangements possessing interesting biological activities for various d...
Open access
Research Article10.9734/BJPR/2014/8382
Aims: The present study was carried out to evaluate the effects of Xylopia aethiopica on serum lipids in fed rats. Also the quantitative phytochemical and nutrient composition was investigated. Study Design: Quantitative phytochemical, proximate analysis and in vivo effect on ser...
Open access
Research Article10.9734/BJPR/2014/12392
Aims: To assess dentist’s knowledge and practice in relation antibiotic prescription and to investigate if they follow the current international guidelines. Methodology: In this cross sectional study a structured and pretested questionnaire was sent to 202 licensed dental practit...
Open access
Research Article10.9734/BJPR/2014/12520
Natural drugs play important and vital role in the modern medicine. It is usually used to cure some ailments which may not be treated by conventional medicine. Natural drugs may exhibit many biological activities, such as antimicrobial, anticancer, anti-diabetic and antioxidant....
Open access
Research Article10.9734/BJPR/2014/12233
Aims: The study was conducted to quantify some phytochemicals present in hydroethanol (absolute ethanol: water 1:1 v/v) and methanol extracts of Harungana madagascariensis stem bark traditionally used in the management of diabetes mellitus. Methodology: Hydroethanol and methanol...
Open access
Research Article10.9734/BJPR/2014/9988
Aims: The study was aimed to evaluate the antibacterial, synergistic and β-lactamase inhibitory potential of O. indicum against ampicillin resistant and Extended Spectrum β-lactamase (ESBL) producing bacterial strains. Methods: Bacterial strains were screened for ampicillin resis...
Open access
Research Article10.9734/BJPR/2014/12343
Aim: The present investigations aimed at studying the effect of sterilization by gamma irradiation on amoxicillin and cefaclor antibiotics. They have been irradiated in solid dry state and the probable changes in physicochemical and microbiological properties were studied Place a...
Open access
Research Article10.9734/BJPR/2014/12251
Aims: This study was aimed at comparing the physicochemical and bioavailability profiles of some brands of Levofloxacin 500mg tablets that are registered in Nigeria by her regulatory authority and to examine the feasibility of interchangeability of the brands. Methodology: The ph...
Open access
Research Article10.9734/BJPR/2014/12355
Anekécia Lauro da Silva, Sheilla Andrade de Oliveira, Jamerson Ferreira de Oliveira, Edna de Farias Santiago, Antônio Sérgio Alves de Almeida Júnior, Íris Trindade Tenório Jacobi, Christina Alves Peixoto, Vinícius Pinto Costa Rocha, Milena Botelho Pereira Soares, Ivan da Rocha Pitta & Maria do Carmo Alves de Lima·Journal of Pharmaceutical Research International·2014
Aims: Verify the potential of the schistosomicidal imidazolidine derivative (5Z)-3-(4-bromo-benzyl)-5-(4-chloro-benzylidene)-4-thioxo-imidazolidin-2-one. Study Design: In this study, we tested the imidazolidinic derivative 3 through in vitro evaluations, cytotoxicity assay and an...
Open access
Research Article10.9734/BJPR/2014/12511
Background: Gastrointestinal nematodes (GIN) are a major threat to sheep productivity and endanger animal welfare worldwide particularly in developing countries. They cause loss of production through mortality, weight loss, reduced milk, meat and wool production. Thus, parasitism...
Open access
Research Article10.9734/BJPR/2014/12936
Aim: To investigate the dichloromethane fraction obtained from an aqueous methanol extract of green stems of Citrus jambhiri Lush. and evaluate the hepatoprotective effect of limonianin. Study Design: Isolation and identification of secondary metabolite and hepatoprotective activ...
Open access
Research Article10.9734/BJPR/2014/12311
A series of new phthalimides 1(a-f) were synthesized via reaction phthalic anhydride with different amino acids under fusion conditions. Esterification of N-phthaloyl acid derivatives 1(a-f) with methanol in the presence of SOCl2 to producing the corresponding esters 2(a-f). Whic...
Open access
Research Article10.9734/BJPR/2014/6355
Aims: This study was design to screen the stem bark extract of Pseudocedrela kotschyi for the presence of phytochemical constituents and evaluate the extract for antimicrobial activity on wide range of pathogenic bacteria and fungi species. Place and Duration of Study: Department...
Open access
Research Article10.9734/BJPR/2014/12163
Md. Tauhid-Ul Islam, Md. Abdus Samad Bhuiyan, Md. Musfequr Rahman Shajjad, Md. Taimuzzaman Sharif, Md. Zakir Sultan, Asma Rahman, Md. Akter Hossain, Abu Asad Chowdhury & Mohammad Shah Amran·Journal of Pharmaceutical Research International·2014
Aims: The present study was designed to evaluate the anti-diabetic as well as prophylactic activity of Jambadyarista and Bohumutrantak Ras in alloxan-induced diabetic rats. Study Design: Study the prophylactic and antiglycemic effects against diabetes of two Ayurvedic drugs ‘Jamb...
Open access
Research Article10.9734/BJPR/2014/11521
Aims: Lemon grass and mango bark serves as one of the medicinal plants used in Nigeria for the treatment of malaria by traditional herbalists. This study was designed to assess the effects of ethanolic extract of lemon grass and mango bark on the cerebral astrocytes of wistar rat...
Open access
Research Article10.9734/BJPR/2014/11772