This paper aimed to study the antioxidant properties of two Nigerian plants Psidium guajava (guava) Myrtaceae and Aloe vera Liliaceae plants which have a broad application in phytomedicine. The plants were assessed by quantifying their individual chemical contents and their 1:1 (...
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Research Article10.9734/BJPR/2014/6989
Carl Parson, Valerie Smith, Christopher Krauss, Hirendra N. Banerjee, Christopher Reilly, Jeanette A. Krause, James M. Wachira, Dipak Giri, Angela Winstead & Santosh K. Mandal·Journal of Pharmaceutical Research International·2013
Aim: To study the efficacy of novel rhenium compounds to treat triple node negative breast cancer. Study Design: Six (6) novel rhenium pentycarbanato compounds (PC1-6) were synthesized and triple node negative breast cancer cell lines HTB-132 and Balb/c mouse kidney cell lines we...
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Research Article10.9734/BJPR/2014/4697
Aim: Present study includes the development and evaluation of superporous hydrogel composites of acrylamide using starch silicone dioxide coprecipitate (SSC) as composite agent. Methodology: Gas blowing method was used for synthesis of superporous hydrogels. Different ingredients...
Open access
Research Article10.9734/BJPR/2014/6277
Aims: This study was designed to determine the effect of a high salt diet on serum bilirubin concentration and to ascertain the impact of treatment with Viscum album on same. Methodology: Twenty male albino wistar rats weighing 150 - 200g were used for this study. After seven day...
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Research Article10.9734/BJPR/2014/7359
Aim: To investigate the interaction of slidenafil and green tea in normal healthy male volunteers using probe drugs (midazolam, CYP3A4 activity). Study Design: Ten healthy males were included in random crossover single dose study. Each volunteer received one tablet of sildenafi...
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Research Article10.9734/BJPR/2014/6905
Aim: This present study investigated the free radical scavenging activities, antihperglycaemic and antihyperlipidaemic activities of ethanol extract of Lawsonia inermis leaves. Study Design: Twenty male rats were randomly and evenly distributed into four groups, and were subseque...
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Research Article10.9734/BJPR/2014/6359
Objective: The present study was designed to evaluate the acute and chronic effects of the methanol extract of Ficus hispida against alloxan (150 mg/kg) induced diabetic rats. Methods: In acute study, hypoglycemic potency of methanol extract of Ficus hispida was assessed by oral...
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Research Article10.9734/BJPR/2014/5187
Background/Aim: Drug utilisation study is essential for evaluating patient care to improve service delivery through awareness creation for appropriate choice of drugs. The study analysed the prescription pattern and associated costs of psychotropic drugs at the outpatient unit of...
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Research Article10.9734/BJPR/2014/5988
Aim: The aim of the present investigation was to perform the precolumn derivatization of Amantadine Hydrochloride (AMT) with phenylisothiocyanate and to develop a RP-HPLC-PDA method for the quantification of Amantadine Hydrochloride-phenylisothiocyanate (AMT-PITC) complex in bulk...
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Research Article10.9734/BJPR/2014/6374
Aims: Objective of the study was to investigate the wound contraction and anti-inflammatory activity of the 50% ethanolic extract of Fumaria indica (Hausskn.) Pugsley (Fumariaceae) by excision wound model and estimation of pro-inflammatory and anti-inflammatory cytokines. Study D...
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Research Article10.9734/BJPR/2014/5387
Aim: Azithromycin is a semisynthetic macrolide antibiotic commonly indicated for use in middle ear, upper and lower respiratory tract infections, bronchitis, and community-acquired pneumonia with a well-established safety and efficacy profile. The antibiotic is usually well toler...
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Research Article10.9734/BJPR/2014/3853
Aims: The aim of the study was to evaluate the effect of the standardized ethanolic extract of Andrographis serpyllifolia leaves on experimentally induced typhoid. Study Design: Single dose of 1 ml Salmonella Typhi (106 CFU/mL) was administered orally to rats to induce typhoid in...
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Research Article10.9734/BJPR/2014/5804
Aims: Upon entrance into the blood stream most nanoparticles bind to an array of proteins forming a “protein corona”. Fibrinogen is the second most abundant blood protein and has been reported to bind to a variety of nanoparticles including metal oxides, polymeric nanoparticles a...
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Research Article10.9734/BJPR/2014/5959
Aims: The main objective of this work was to observe the analgesic activity of Manilkara zapota (leaves) on mice. Study Design: The Present study was designed to observe pharmacological activities of the crude extracts of the plant Manilkara zapota (leaves). The study protocol co...
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Research Article10.9734/BJPR/2014/5941
Aims: The current study was aimed at evaluating the phytochemical profile and in vitro bacteria growth inhibitory potential of different solvent leaf extracts of V. amygdalina from northern Ghana. Study Design: Different solvent extracts of the plant were quantitatively and quali...
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Research Article10.9734/BJPR/2014/3200