Aims: Preparation of mucoadhesive buccal films able to deliver the meloxicam drug to the site of application through oral mucosal tissues. This dosage form is advantageous due to absence the problems of the ordinary dosage forms. Study Design: In this research, it was prepared a...
Open access
Research Article10.9734/BJPR/2013/4288
The root and leaf extracts of Cichorium intybus were investigated for antibacterial activity against gram negative pathogenic bacteria viz. Escherichia coli and Pseudomonas aeruginosa. The sensitivity was analyzed using Disk diffusion method at various concentrations where zone o...
Open access
Research Article10.9734/BJPR/2013/3887
The matrix metalloproteinase-13 (MMP-13) inhibitory activities of carboxylic acid based compounds, in presence and absence of bovine serum albumin (BSA), have been analyzed quantitatively in terms of chemometric descriptors. The statistically validated quantitative structure-acti...
Open access
Research Article10.9734/BJPR/2013/3903
Aim: The intent of present study is to formulate fast dissolving tablets of flurbiprofen using different superdisintegrants to improve the dissolution and bioavailability. Place and Duration of Study: Jyothishmathi Institute of Pharmaceutical Sciences, Karimnagar, Andhra Pradesh,...
Open access
Research Article10.9734/BJPR/2013/3979
Possible interaction between carbamazepine and different HPMC grades was done using DSC thermal analysis. The results indicated that the drug was compatible with these grades. Seven preparations of carbamazepine 200 mg controlled release tablets were prepared by wet granulation m...
Open access
Research Article10.9734/BJPR/2013/3923
Aims: The leaves of Carica papaya Linn. (Caricaceae) have been traditionally used as a medicine against some forms of liver diseases. Its hepatoprotective activity against hepatotoxicants like CCl4 and paracetamol has been scientifically proved in animals. The aim of the present...
Open access
Research Article10.9734/BJPR/2013/4517
Aims: To determine the immunomodulatory effect of aqueous extracts of Auricularia sp and Pleurotus sp mushrooms using an immunosuppression animal model. Study Design: Pre-clinical experimental study. Place and Duration of Study: Department of Pharmacology and Therapeutics, Colleg...
Open access
Research Article10.9734/BJPR/2013/1994
Aim: This study was designed to determine the antitumor and antioxidant properties of crude methanol extract from the leaves of Plumeria acuminata (Apocynaceae) (MEPA) against Ehrlich Ascites Carcinoma (EAC) bearing Swiss albino mice. Study Design: Study design is methodology, me...
Open access
Research Article10.9734/BJPR/2013/4472
Aims: Study the release of fluconazole from different O/W creams and PEG ointments. Study Design: In this study, different formulations were prepared with changing one of the added excipients and study the effect of this change on the drug release and then the selected formulatio...
Open access
Research Article10.9734/BJPR/2013/3702
Aims: The aim of the study was to investigate chronic anti-inflammatory activity of ethanolic extract of the leaves of Clerodendrum viscosum (EELCV) by carrageenin induced paw oedema in Wistar albino rats. Study Design: Prospective. Place and Duration of Study: Dept of Pharmacolo...
Open access
Research Article10.9734/BJPR/2013/3505
Aims: To study the susceptibility profile of methicillin-resistant Staphylococcus aureus (MRSA) isolates from orthopaedic patients to antibiotics and methanolic extracts of Parkia biglobosa. Background: Antimicrobial resistance in Staphylococcus aureus has attained alarming propo...
Open access
Research Article10.9734/BJPR/2013/2080
Aims: 1) To study the effect of some formulation variables on drug load, encapsulation efficiency, swelling ratio, mucoadhesion and drug release. 2) Optimize the mucoadhesion capabilities for targeting drug absorption and release-controlling capabilities of alginate beads. Method...
Open access
Research Article10.9734/BJPR/2013/3020
Aims: The present study was conducted to evaluate the hepatoprotective effect of hydroalcoholic extract of Drynaria quercifolia fronds (Dq), its fractions and isolated compound (Dq-4) from ethyl acetate (EA) fraction. Place and Duration of Study: Department of Pharmacognosy and D...
Open access
Research Article10.9734/BJPR/2013/3620
Aims: To develop block copolymer crosslinked nanoassemblies (CNAs) that co-entrap an imaging dye (Acridine Yellow: AY) and therapeutic agent (doxorubicin: DOX) as novel nanoparticle drug carriers for a combined application of drug delivery-based therapy and diagnostic imaging tec...
Open access
Research Article10.9734/BJPR/2013/4574
Aims: The present study was undertaken to explore in vivo antioxidant potential of ethanol extracts of Nyctanthes arbor-tristis leaf and stem in adjuvant induced arthritic rats. Methodology: Arthritis induced rats were administered with extract of Nyctanthes arbor-tristis leaf an...
Open access
Research Article10.9734/BJPR/2013/3295