Recently, the residues or by-products of agriculture industry take attention for their valuable source of natural antioxidants. Taif rose (Rosa damascena trigintipetala Dieck) is considered one of the most important economic products of Taif, Saudi Arabia. In this study, the anti...
Open access
Research Article10.9734/BJPR/2012/1493
Aims: The purpose of this in vitro and ex vivo study was to prepare and characterise ocular minitablets of piroxicam based on different polymeric matrices and to evaluate their potential to provide prolonged and controlled drug release to ocular tissues after surface administrati...
Open access
Research Article10.9734/BJPR/2012/1653
Aims: To determine the effect of Piper sarmentosum (Ps) leaf extract on biomechanical strength and trabecular structure of the bones of glucocorticoid-induced osteoporotic rats. Study Design: Administration of crude extract to rats with excessive glucocorticoids. Place and Durati...
Open access
Research Article10.9734/BJPR/2012/1435
Aims: To investigate the petroleum ether extract of the unripe fruit of Solanum macrocarpum L. (Solanaceae) for its chemical components and its antimicrobial properties against Gram positive, Gram negative bacteria and fungi. Study Design: Experimental study. Place and Duration o...
Open access
Research Article10.9734/BJPR/2012/1207
Aims: To evaluate the effects of aqueous extract of V. amygdalina on lipid profile and lipid peroxidation status in rats. Study Design: Experimentation. Place and Duration of Study: Departments of Biochemistry and Pharmaceutical Chemistry, University of Benin, Benin city, Nigeria...
Open access
Research Article10.9734/BJPR/2012/1095
Aims: To carry out phytochemical screening and investigate hypoglycemic effect of aqueous Blighia sapida root bark extract (ABRE) on normoglycemic Albino rats. Study Design: Extraction and administration of bioactive extract. Place and Duration of Study: Department of Biochemistr...
Open access
Research Article10.9734/BJPR/2012/1056
The amino acid profile and the effects of the seed extracts of Sphenostylis sternocarpa, Monodora myristica and Mucuna sloanei were studied based on their ability to inhibit haemoglobin polymerization and improve the Fe2+/Fe3+ ratio of sickle cell erythrocytes. The samples were f...
Context: Studies have identified that concurrent administration of methionine and acetaminophen (paracetamol) prevents tissue damage and both methionine and acetaminophen at high doses can induce oxidative stress. Antioxidants mediate against oxidative stress. Moreover, folic aci...
Aims: Dioclea reflexa Hook F., is a woody vine widely distributed within tropical Africa and South America, in Nigeria flour prepared from the seeds is used as a soup thickener. The objectives of this study were to extract and modify the native gum from the seeds of D. reflexa, a...
Although drug interactions with Acarbose are uncommon, there is a possibility for interference with the pharmacokinetic behaviors of concomitantly administered drugs. The present study was designed to evaluate the possible drug interactions between Acarbose and orally administere...
Open access
Research Article10.9734/BJPR/2012/1109
Aim: To investigate interpolymer complexes (IPCs) formation between carbopol and cationic polymers such as chitosan and Eudragit E for oral controlled drug delivery systems. Methodology: The prepared IPCs were investigated using Fourier transform infra-red spectroscopy (FT-IR) an...
Open access
Research Article10.9734/BJPR/2012/1049
Extracts of Parkia biglobosa stem bark is used in Nigerian traditional medicine (NTM) to treat malaria, diarrhea and pains. To establish the toxicity profile of the medicine such parameters as the lethal dose (LD50) as well as effects on body functions and organs were evaluated i...
Aims: To evaluate the aqueous as well as ethanolic extracts of Tridax procumbens L., (Asteraceae) against various bacterial pathogens including strains obtained from community acquired and nosocomial infections. Study design: Experimental study. Place and Duration of Study: Depar...
Aims: The purpose of this study was to provide factorial analytic findings, construct validation and normative data for the Malaysian diabetic patients. Gender difference was also examined with racial response to PSS-10. Study design: Population base cross sectional survey. Place...
The ethanol extract of the leaf of Chromolaena odorata (Linn) was assessed for free-radical-scavenging and antioxidant potentials. Ability of the extract to scavenge reactive intermediates (superoxide ion O2·-, hydrogen peroxide H2O2, nitric oxide NO˙, hydroxyl radical OH˙) an...