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All published articles 7450

Occurrence of Perforated Appendicitis in Patients Subjected to Appendectomy for Acute Appendicitis

Mehwish Ali, Deen Muhammad, Vijay Kumar & Karim Bux · Journal of Pharmaceutical Research International · 2022

Objective: To determine the frequency of perforated appendicitis among patients subjected to appendectomy for acute appendicitis. Methodology: A cross-sectional research was performed at the Department of Surgery, Bolan Medical College, Quetta between June 2019 to March 2021. In...

Open access Research Article 10.9734/jpri/2022/v34i46B36389

Frequency of Gestational Thrombocytopenia in Pregnant OPD Patients: Study in a Tertiary Care Hospital

Kaweeta Kumari, Faiz Bakhtawar, Sumbul Ismail, Tooba Shaukat Butt, Nand Lal Dhomeja & Uniza Ghani · Journal of Pharmaceutical Research International · 2022

Objective: Gestational thrombocytopenia can lead to fatal complications. Therefore, the present study aimed to evaluate the frequency of Gestational Thrombocytopenia in pregnant patients attending antenatal outpatients department (OPD) at a tertiary care hospital, Karachi. Method...

Open access Research Article 10.9734/jpri/2022/v34i46B36390

Outcome of Germ Cell Tumors in Children after Surgical Management; A Longitudinal Study

. Sumaira, Mumtaz Ahmed Qureshi, Shazia Perveen, Ishrat Mahtam, Uzma Imam & Muhammad Nadeem Chohan · Journal of Pharmaceutical Research International · 2022

Aim: To assess the outcome of germ cell tumors in children after surgical management. Study Design: A longitudinal study. Place and duration: Pediatric surgery and oncology department of the national institute of child health Karachi from January 2017 to December 2018. Methodolog...

Open access Research Article 10.9734/jpri/2022/v34i46B36393

Updates in the Epidemiology of Fatty Liver and its Consequences in Saudi Arabia: A Review

Badriah Mohammed Alanazi · Journal of Pharmaceutical Research International · 2022

The occurrence of non-alcoholic fatty liver disease has exponentially increased worldwide. A considerable majority of cases advance to non-Alcoholic Steatohepatitis in the nonexistence of therapeutic measures, which increases morbidity and death. Because the initial phases of the...

Open access Research Article 10.9734/jpri/2022/v34i46B36387

Nanoparticles Loaded Mucoadhesive Buccal Patches - Review

M. Sabareesh, P. Suma, M. Venkata Ravi & Anna Balaji · Journal of Pharmaceutical Research International · 2022

Drug distribution for both local and systemic conditions is significantly facilitated by buccal methods of administration. When a rapid beginning of action is necessary, they have proven to be a potent substitute for the conventional oral route, the buccal route is regarded as pa...

Open access Research Article 10.9734/jpri/2022/v34i46B36388

Clinical Characteristics of Hospitalized and Home Isolated Covid-19 Patients with Type 1 Diabetes

Saba Zulfiqar, Mohammad Arif Sarwar, Talha Tahir, Javaria Hafeez, Fawzia Shahid & Rija Shahid · Journal of Pharmaceutical Research International · 2022

Aim: To investigate pathological conditions of COVID-19 individuals having type 1 diabetes throughout hospitalization and home isolation. Methods: This retrospective analysis included 32 COVID-19 in addition T1D individuals who sought therapy at Services Hospital, Lahore, between...

Open access Research Article 10.9734/jpri/2022/v34i46B36385

Study on Frequency of Impaired Lung Function in Treated Tuberculosis Patients in Tertiary Care Hospital of Pakistan

Riaz Hussain, Sagheer Hussain, Mirza Saifullah Baig, Nisar Ahmed Rao, Rizwan Ali, Safdar Ali & Syed Qalb-i-Hyder · Journal of Pharmaceutical Research International · 2022

Background: Pulmonary impairment is a common manifestation in previously treated pulmonary tuberculosis (PTB) patients. Approximately 40-60% of patients with history of complete anti-tuberculosis therapy (ATT) developed the obstructive, restrictive or mixed patterns of lung disea...

Open access Research Article 10.9734/jpri/2022/v34i46B36383

In-vitro Study of the Inhibitory Activity of the Fractions of Onion (Allium cepa) and Shallot Bulb (Allium ascalonicum) Extracts on Angiotensin-Converting Enzyme (ACE)

Celine Angelica Garcia, Khristy Joy Flores, Mikko Gamalo, Gezer Gandeza, Naomi Francise Garcia, Jenn Lori Gepaya, Maria Gerber, Shera Heart Go, Ore May Faith Gomez, Sarah Myza Katrina Guinta, Roanne Paula Herrero, Jo Anne Himagan, Cecile Melisse Derecho & Genevieve D. Tupas · Journal of Pharmaceutical Research International · 2022

The impact of hypertension as being the leading cause of death in industrialized societies pressed the importance of low-cost and accessible therapeutic agents present in food sources. This study was undertaken to evaluate the in-vitro Angiotensin-converting Enzyme (ACE) inhibito...

Open access Research Article 10.9734/jpri/2022/v34i46B36384

Design, Development and in vitro Assessment of Flurbiprofen Microemulsion Gel for Transdermal Drug Delivery

Heera Battu, Nimmathota Madhavi & K. Nithiyanand Reddy · Journal of Pharmaceutical Research International · 2022

The aim of current research is to develop flurbiprofen microemulsion gel for transdermal delivery. To prepare a microemulsion oil, surfactant and co-surfactant selection is one of the important criteria. Selected to prepare different ratios of oil and surfactant mixture using ter...

Open access Research Article 10.9734/jpri/2022/v34i46A36381

Phytochemical Analysis and Anthelmintic Activity of Ethanolic Extracts of Gmelina arborea on the Bovine Parasite Onchocerca ochengi

Mando Ndou Bertrand, Bambe Raymond, Djongra Mathieu, Koga Mang-Dobara & Ndjonka Dieudonné · Journal of Pharmaceutical Research International · 2022

Aims: This study was aimed at analyzing the phytochemical constituents, evaluated the in vitro filaricidal activities of the ethanolic extracts of G. arborea on Onchocerca ochengi and carried out the acute and sub-acute toxicity on rats. Place and Duration of Study: The work took...

Open access Research Article 10.9734/jpri/2022/v34i46A36378

Severity of Splenic Trauma and Its Surgical Outcome among Patients Presented at Liaquat University Hospital, Pakistan

Suhail Ahmed Soomro, Riaz Ahmed Shah, Abdul Sattar Abro, Mushtaq Ahmad Abbasi, Muhammad Fahim Ahsan & Shahnawaz Khatti · Journal of Pharmaceutical Research International · 2022

Objective: To determine the severity of splenic trauma and its surgical outcome among patients presented with abdominal blunt trauma at surgical emergency of Liaquat University Hospital Jamshoro (Hyderabad) Material and Methods: This prospective case series study was conducted in...

Open access Research Article 10.9734/jpri/2022/v34i46A36380

Ayurvedic Shodhan Treatment Approach for the Management of Ksheenshukra (Oligozoospermia)

Lokesh Kumar, Pankaj Kumar Katara & Sonal Chaturvedi · Journal of Pharmaceutical Research International · 2022

The main cause of a childless couple's lack of societal support is the depressing ignorance and maltreatment of the causes of childlessness and its treatment. Childless couples are socially and emotionally vulnerable in many parts of the world because of this isolation. The press...

Open access Research Article 10.9734/jpri/2022/v34i46A36376

Molecular Docking of Mangrove Plant as Therapeutic Agent to Treat Non-Small Cell Lung Carcinoma

Haidar Ali Hamzah, Putri Mahirah Afladhanti, Muhammad Despriansyah Romadhan, Dessy Agustini, Raehan Satya Deanasa & . Theodorus · Journal of Pharmaceutical Research International · 2022

Background: Cancer is one of the biggest health problems worldwide, with lung cancer as the first rank in the number of new cases and deaths. Non-small cell lung carcinoma (NSCLC) is a type of lung cancer that accounts for about 85% of all lung cancer cases. Previous research ide...

Open access Research Article 10.9734/jpri/2022/v34i46A36375

Assessment of in vitro Quality Tests of Paracetamol Brands 500mg in Karachi, Pakistan

Hira Akhtar, Muhammad Ali, Salman Ashfaq Ahmad, Rabia Humayoon, Khwaja Zafar Ahmed & Hafiz Sohaib Hassan · Journal of Pharmaceutical Research International · 2022

Objective: The main purpose of this study is to perform the quality assessment of three different brands of Paracetamol tablets (500 mg) available in local market of Karachi, Pakistan. Methodology: Several pharmacopeial and non-pharmacopeial tests were applied on selected brands...

Open access Research Article 10.9734/jpri/2022/v34i46A36372

Plaque Control Efficacy: Interdental Brushes versus Dental Floss

Madiha Sultan, Saima Qureshi, Asher Jamelle, Saqib Rashid, Mehwish Feroz Ali & Umair Khero · Journal of Pharmaceutical Research International · 2022

Aims: In this study, we compared plaque control efficacy between interdental brushes & dental floss for the prevention of periodontal disease (gingivitis). We also investigated the convenient method for plaque control among these two interdental cleaning methods in routine. S...

Open access Research Article 10.9734/jpri/2022/v34i46A36373