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Phytoconstituents and Therapeutic Aspects of Neem (Azardirachta indica): A Review

Nandita Mandi, Reena Sharma & . Sushma · Journal of Pharmaceutical Research International · 2022

It has been centuries since neem plant is known to have medicinal importance to the humans. Whole plant parts have uncountable properties such as anti-bacterial, anti-malarial, anti- fungal, and anti-cancerous. Worldwide the extract from different parts of this plant is being use...

Open access Research Article 10.9734/jpri/2022/v34i45B36367

Chemical Constituents and Pharmacological Effects of Dolichandrone Species: A Review

P. Thirupathy Kumaresan, N. Venkateshan, M. Dhineshmani, M. R. Junuha, G. Shifama, Uma, T. Kateeja Beevi & T. Sri vaishnavi · Journal of Pharmaceutical Research International · 2022

Previously conducted study confirmed that Dolichandrone species showed antimicrobial, anti-oxidant, and antinociceptive properties, as well as anti-cancer, thrush therapy, and fish poisoning effects. This review focuses on the chemical constituents and pharmacological effects of...

Open access Research Article 10.9734/jpri/2022/v34i45B36368

Challenges of Exclusive Breastfeeding among Working Class Women in a Teaching Hospital South East, Nigeria

Adaobi Maryann Ibekwe, Emmanuel I. Obeagu, Chisom Evelyn Ibekwe, Chinonye Onyekwuo, Chioma Vivian Ibekwe, Amarachukwu Doris Okoro & Chioma Blessing Ifezue · Journal of Pharmaceutical Research International · 2022

This research work seeks to investigate the challenges of exclusive breastfeeding among working class mothers in Nnamdi Azikiwe University Teaching Hospital Nnewi Anambra State Nigeria. The objective of the present study is to investigate the attitude of working mothers to exclus...

Open access Research Article 10.9734/jpri/2022/v34i46A36371

Evaluation of Hypoglycemic and Hypolipidemic Activities of Methanolic Leaf Extract of Garcinia gummi-gutta Linn by HFD with Low Dose STZ Induced Type II Diabetes Mellitus on Rats

G. Sivakumar & Solly Varghees · Journal of Pharmaceutical Research International · 2022

Objective: The present study aimed to evaluate the hypoglycemic and hypolipidemic activities of methanolic leaf extract of Garcinia gummi-gutta Linn. by HFD with low dose STZ induced T2DM on rats. Materials and Methods: The animals were divided into five groups of six animals, an...

Open access Research Article 10.9734/jpri/2022/v34i45B36365

Observational Study of Covid-19 Cases and Off-label Drugs to Manage Complications during First and Second Wave

Sushantha Kumar Das, Nanditha Doddikindi, Prathyusha Thoda, Shashank Jindam, Sai Harshitha Vajenepalli & T. Rama Rao · Journal of Pharmaceutical Research International · 2022

Background: Initially Covid-19 complication treatment was almost nil and focused only on supportive measures. Various off-label drugs were utilized globally to obtain better outcomes; the same was practiced by the Indian healthcare fraternity. We have aimed to review the utilizat...

Open access Research Article 10.9734/jpri/2022/v34i45B36366

Impact of Hydroxyurea on Blood Transfusion Rate in Patients of Beta-Thalassemia Major

Sumair Memon, Ikram Din Ujjan, Humaira Ashraf, Tasneem Memon, Faria Sana & Shujaullah Talib · Journal of Pharmaceutical Research International · 2022

Objective: To determine the effectiveness of hydroxyurea on the blood transfusion rate in patients with beta-thalassemia major. Materials and Methods: This cross-sectional study was held in the Department of Genetics and Molecular Biology/Pathology at LUMHS Jamshoro, and Diagnost...

Open access Research Article 10.9734/jpri/2022/v34i45B36364

Perception, Patterns and Facts: A Study Based on Hand Hygiene among Pharmacy Clerkship Students during COVID-19 Epidemic in Karachi

Maqsood Ahmed Khan, Saira Shahnaz, Shazia Alam Khan, Mehwish Murad Ali, Faiza Khan, Sana Ghayas & Sadia Suri Kashif · Journal of Pharmaceutical Research International · 2022

Aims: The objective of the study is to explore the knowledge and attitude towards hand hygiene practices among 4th year and 5th year clerkship pharmacy students in a private medical university in Karachi, Pakistan. Methodology: A cross- sectional study was conducted for the perio...

Open access Research Article 10.9734/jpri/2022/v34i45B36363

The Assessment of the Allium sativum and Tamarix aphylla Comparative and Combined Antioxidant Potential

Shahid Ullah, Fahim Ullah Khan, Laiq Zaman, Saira Abbas, Mir Sadiq Shah, Jamil Ur Rehman, Autif Hussain Mangi, Abdu Razzaq Khan, Batab Khan, Surayia Shahab Rani, Sana Gul & Adnan khattak · Journal of Pharmaceutical Research International · 2022

Many diseases, including cancer and diabetes mellitus, are caused by reactive oxygen species (ROS). Allium sativum (Garlic) contains vitamins A, B, and C, as well as effective drugs like insulin, alliin, mineral salts, mucilages, allicin, and volatile oils. Garlic has antioxidant...

Open access Research Article 10.9734/jpri/2022/v34i45B36359

Use of Liquid Pharmaceutical Forms and Correct Handling of Solid Forms in the Dysphagic Patient

Edoardo Marovino, Amelia Morgillo, Marcello Mazzarella & Maria Francesca Randazzo · Journal of Pharmaceutical Research International · 2022

Introduction: The presence of dysphagia is a rather common event, both physiologically in elderly people and the presence of neurological, maxillofacial, or upper digestive pathologies. Many drugs are routinely taken in solid form for the convenience of use, however, in such pati...

Open access Research Article 10.9734/jpri/2022/v34i45B36358

An Overview of Pharmacological Efficacy and Chemical Moieties of Strobilanthes ciliata Nees. (Acanthaceae)

Anusree Prakash & . Nishtha · Journal of Pharmaceutical Research International · 2022

The expensive modern drugs have been replaced by medicinal plants these days. Strobilanthes ciliata Nees as called “Sahachara” is mainly used in the Indian system of drug and medicine and has shown biochemical activities that are – anti-microbial, anti-cancerous, anti-inflammator...

Open access Research Article 10.9734/jpri/2022/v34i45A36357

A Repertoire of Antibody after Complete Vaccination of Covishield Concerning Severe Acute Respiratory Syndrome Coronavirus- 2- an Observational Study

R. S. Anusreeraj, Shaiju S. Dharan, Abhijith Biju, S. Aiswarya, R. Alfiya & Alina Rajan · Journal of Pharmaceutical Research International · 2022

Aim: To assess the repertoire of antibody after complete vaccination of covishield concerning SARS-CoV-2. Study Design: Observational Study. Place And Duration of Study: The study was conducted in community area in Kerala for a duration of six months from January 2022 to June 202...

Open access Research Article 10.9734/jpri/2022/v34i45A36356

Outcomes of Intraplaque Verapamil Injection for Treatment of Peyronie’s Disease

Faraz Ahmed, Saddam Hussain & Muhammad Hassam Ullah · Journal of Pharmaceutical Research International · 2022

Objective: To determine the outcomes of intraplaque verapamil injection for treatment of Peyronie's disease. Aim: The purpose of this study is to evaluate the outcomes & efficacy of intraplaque verapamil injection in Peyronie’s disease management. Methods: The quasi experimen...

Open access Research Article 10.9734/jpri/2022/v34i45A36352

Development and Evaluation of Fast Dissolving Liquisolid Haloperidol Tablets

Aya M. Eisa, Nagia A. El-Megrab & Hanan M. El-Nahas · Journal of Pharmaceutical Research International · 2022

Aim: The aim of this study was to design fast dissolving tablets (FDT) of the anti -psychiatric drug, Haloperidol in liquisolid forms as a way to enhance its dissolution profile and anti-psychiatric effect. Methodology: Solubility studies of Haloperidol in various solvents and su...

Open access Research Article 10.9734/jpri/2022/v34i45A36353

Multi Drug Resistance: A Continuous Challenge by a Century Old Mycobacterium Tuberculosis

Nasreen Qazi, Shah Nawaz Jamali, Ayesha Aftab, Imran Ahmed, Sadat Memon & Gunesh Kumar · Journal of Pharmaceutical Research International · 2022

Background: Tuberculosis is a mycobacterial infection caused by mycobacterium tuberculous bacillus. Anti-tuberculous drugs are drugs used to treat tuberculosis which include first line anti-tuberculosis drugs used to treat tuberculosis initially when the infection is non-resistan...

Open access Research Article 10.9734/jpri/2022/v34i45A36354