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All published articles 7450

Relationship of Neck Circumference and Obstructive Sleep Apnea: A Cross-sectional Study in Pakistani Population

Faisal Asad, Madiha Moin, . Ubedullah, Saif Ur Rehman & Fasih Ur Rehman · Journal of Pharmaceutical Research International · 2022

Objective: This study aimed to determine the reliability of neck circumference in comparison to BMI for a measure of Obstructive Sleep Apnea and determine the interaction between neck circumference and the severity of apnea in the Pakistani adult population. Materials and Methods...

Open access Research Article 10.9734/jpri/2022/v34i44A36333

Effect of Chronic Oral Exposure to Overdose of Cough Syrups on Rate of DNA Fragmentation in Liver and Brain of Wistar Rats

Abolanle A. A. Kayode, Omowumi T. Kayode, Auwal A. Mohammad & Great O. Alabi · Journal of Pharmaceutical Research International · 2022

This study was designed to determine the effect of chronic oral exposure of overdose of cough syrups containing codeine (CSC) and dextromethorphan (DXM) on the rate of deoxyribonucleic acid (DNA) fragmentation in the liver and brain of Wistar rats. Forty-five rats divided into 9...

Open access Research Article 10.9734/jpri/2022/v34i44A36332

A Comparison of Ivermectin and Non Ivermectin Based Regimen for COVID-19 in Abuja: Effects on Virus Clearance, Days-to-discharge and Mortality

Y. Thairu, O. E. Babalola, A. A. Ajayi, Y. Ndanusa, J. O. Ogedengbe & Omede O. · Journal of Pharmaceutical Research International · 2022

Aim: To compare outcomes from ivermectin (IVM) - and non-ivermectin (NIVM)-based treatments for COVID-19 in Abuja, Nigeria. Methods: Sixty-one consecutive virology-proven cases were recruited and managed with IVM-based regimes. A subsequent cohort of 26 patients was treated with...

Open access Research Article 10.9734/jpri/2022/v34i44A36328

An Investigation of Insulinotropic Potential of Herbal Plants for Management of Diabetes

Yousef Ahmed Saleh Haimed, Pankaj Kumar Sharma, Deepak Kumar Jha & Jaya Sharma · Journal of Pharmaceutical Research International · 2022

The Insulinotropic hormone glucagon-like peptide-1, which has been proposed as a modern treatment for management of diabetes, is metabolized extremely with the aid of dipeptidyl peptidase-IV. Inhibitors on dipeptidyl peptidase-IV enhance the level of glucagon-like peptide-1, as h...

Open access Research Article 10.9734/jpri/2022/v34i44A36329

Knowledge and Awareness of Digital Dentistry among the Dental Students of Karachi, Pakistan: Cross-Sectional Study

Lubna Memon, Zeeshan Ahsan, Muhammad Faraz, Saman Arif, Bharat Kumar & Irsam Haider · Journal of Pharmaceutical Research International · 2022

Aim: To evaluate Knowledge and Awareness of Digital Dentistry among the Dental Students of Karachi, Pakistan. Study Design: Descriptive Cross-Sectional study. Place and Duration of Study: Different dental colleges in Karachi from 15-06-2021 to 1-07-2021. Methodology: This cross-s...

Open access Research Article 10.9734/jpri/2022/v34i44A36330

The Antioxidant Modulating Properties of Justicia carnea Extract on Sheep Red Blood Cells Immunized Mice

Benedict Bolakponumigha Iwetan, Atuboyedia Wolfe Obianime, Lawrence Oberhiri Ewhre & Godfrey Rume Kweki · Journal of Pharmaceutical Research International · 2022

Aims: Inflammatory cytokines as well as exogenously invading antigens among others are keenly involved in the generation of oxidative stress such as reactive oxygen species, reactive nitrogen species capable of causing related diseases. hence this study aimed at evaluating the In...

Open access Research Article 10.9734/jpri/2022/v34i43B36327

Meta-analysis on the Effectiveness and Safety of Propolis Preparation in the Treatment of Aphthous Ulcers

Yang Jinlong & Luo Wenhua · Journal of Pharmaceutical Research International · 2022

Objective: To systematically evaluate the effectiveness and safety of propolis preparation in the treatment of aphthous ulcers in order to provide evidence-based references for its clinical treatment. Methods: Databases, such as CNKI, VIP, Wanfang, CBM, PubMed, EMbase, Cochrane L...

Open access Research Article 10.9734/jpri/2022/v34i43B36326

The Evaluation of Prevalence and Hematological Parameters for Assessment of Severity of Coronavirus Infection

Umair Ali Soomro, Majid Ali Hingoro, Nazir Ahmed Pathan, Allah Wadhayo Kalo, Rasheed Ahmed Soomro & Qandeel Abbas Soomro · Journal of Pharmaceutical Research International · 2022

Objectives: We determined the prevalence of coronavirus (COVID-19 virus) infection on the basis of age, sex, clinical presentation and risk of ABO Blood Groups antigens with COVID-19 virus. We also highlight the Hematological Parameters such as neutrophils to lymphocytes ratio an...

Open access Research Article 10.9734/jpri/2022/v34i43B36323

Antioxidant Activities of Aqueous Leaf Extract of Anacardium occidentale (Cashew) on Lead Acetate-Induced Cerebellar Toxicity in Wistar Rats

Ezinne C. Oviosun, G. E. Anyanwu, E. A. Esom & S. O. Nweze · Journal of Pharmaceutical Research International · 2022

Aim: The aim of the present study was to investigate the antioxidant effect of aqueous leaves extract of Anacardium occidentale (A.O) on lead-induced toxicity in the cerebellum of wistar rats. Methods: Thirty wistar rats were randomly divided into six groups of five rats each. Gr...

Open access Research Article 10.9734/jpri/2022/v34i43B36324

Knowledge towards Biochemical Parameters of COVID–19 amongst First Professional Year Medicine Students: A Cross-sectional Study

Prafulkumar Ramteke, Madhur M. Gupta & Deepali M. Wanjari · Journal of Pharmaceutical Research International · 2022

The latest pandemic coronavirus disease (COVID-19) has been linked with mounting morbidity and mortality and this has shocked the existence of the world-wide population. Human activities and acquaintance of the biochemical parameters in medical students during the crisis is impor...

Open access Research Article 10.9734/jpri/2022/v34i43B36320

Clinical Efficacy and Safety of Oral Apremilast: Treatment Analysis for Chronic Plaque Psoriasis

Meet Barbhaya, Afiya Modasiya, Anu Patel, Nirav Bapat & Krina Patel · Journal of Pharmaceutical Research International · 2022

Background: Apremilast is an oral, selective phosphodiesterase-4 (PDE-4) enzyme inhibitor, approved by the US-FDA for management of moderate to severe plaque psoriasis. Apremilast belongs to class of drug that function by modulating pro-inflammatory cytokines and have a low molec...

Open access Research Article 10.9734/jpri/2022/v34i43B36316

Waist to Height Ratio is a Better Predictor of Non-Alcoholic Fatty Liver Disease in the South Asian Population

Sandeep Kumar, Farina M. Hanif, Rajesh Mandhwani, Zain Majid, Asha Devi, Rani Tulsi & Nasir Luck · Journal of Pharmaceutical Research International · 2022

Introduction: Numerous obesity indices have been developed that predict non-alcoholic fatty liver disease (NAFLD). We in our study aimed at evaluating a few of these tools including waist to height ratio (WHtR), waist circumferences (WC), body mass index (BMI) and fatty liver ind...

Open access Research Article 10.9734/jpri/2022/v34i43B36318

Impact of Coronavirus Disease Pandemic on Antenatal Care Utilization among Primigravida Women in Asir Region, Saudi Arabia

Hanoof Alqhatani, Mohammed S. Aldalham Alqahtani, Faris A. Alasmre, Khaled Abdulwahab Amer, Abdulrahman Ali Aldosari, Basel Mohammed Saleh Althubait, Abdulrahman Abdullah Mofreh Al Mudawi & Mushary Saeed A. Alqahtani · Journal of Pharmaceutical Research International · 2022

Background: By the end of 2019, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was diagnosed in Wuhan, Hubei province, China. In Saudi Arabia, the government applied prompt preventive measures against coronavirus disease 19 (COVID-19). COVID-19 associated restrict...

Open access Research Article 10.9734/jpri/2022/v34i43B36319

In vitro Callus Induction of Catunaregam spinosa Using Leaves as Explant

P. K. Lawrence, W. T. P. S. K. Senarath & M. L. A. M. S. Munasinghe · Journal of Pharmaceutical Research International · 2022

Aims: C. spinosa (Family Rubiaceae) is a valuable medicinal since years ago. A protocol was developed including best sterilization and best medium for callus induction of C. spinosa using leaf discs as explants. Methodology: Sterilization protocol optimized using different concen...

Open access Research Article 10.9734/jpri/2022/v34i43A36313

Inhibitory Effect on Hexokinase II by Benzimidazoles and the Insight into Interactions

Hillary J. Navarro, Jhawn G. Saul, Andrew E. Huckleby & Sung-Kun Kim · Journal of Pharmaceutical Research International · 2022

Background: Benzimidazoles are aromatic, heterocyclic organic molecules which exhibit pharmacological potential as anti-inflammatory, antiulcer, anti-hypertensive, anticancer agent, and anthelmintic treatments. The benzimidazoles could inhibit human hexokinase II, which is a crit...

Open access Research Article 10.9734/jpri/2022/v34i43A36311