Skip to content

All published articles 7450

Comparative Evaluation of Dexmedetomidine, Ketamine & their Combination for Epidural Analgesia in Orthopedic Surgeries of the lower Limb

Deeksha Mishra & Vivek Chakole · Journal of Pharmaceutical Research International · 2022

Background: Epidural anesthesia is a perioperative pain control treatment that has a variety of applications in anaesthesiology. It could be used as as a primary anaesthetic, although it's most usually utilised as an adjuvant for management of pain.  It could be a one-time shot o...

Open access Research Article 10.9734/jpri/2022/v34i43A36310

Antagonistic Potential of Lophophora williamsii, Vinca minor and Hydrastis canadensis against Dental Caries Associated Bacteria

Hafiz Muhammad Ahmad, Iftikhar Ali, Anila Zaman & Muhammad Mansoor Hafeez · Journal of Pharmaceutical Research International · 2022

Introduction: Dental caries is a bacterial illness that causes localized disintegration and loss of calcified components in the teeth. Different plant extracts have been used to assess the anti-bacterial activity against the pathogens known to induced dental caries. Objective: Th...

Open access Research Article 10.9734/jpri/2022/v34i43A36307

Incidence of New-onset Atrial Fibrillation in Patients Presenting with Acute St-elevation Myocardial Infarction

Kamran Awan Nadeem, Javed Khurshed Shaikh, Muhammad Hashim Kalwar, Muhammad Hassan Butt, Gulzar Ali & Bashir Ahmed Solangi · Journal of Pharmaceutical Research International · 2022

Aim: This study aims to find out the incidence of atrial fibrillation new onset in STEMI patients receiving primary PCI Sample: A total of 169 patients have included after sample size calculation by using WHO sample size calculator version 2.0. Study Design: Descriptive cross-sec...

Open access Research Article 10.9734/jpri/2022/v34i43A36308

Anti-inflammatory, Antipyretic and Analgesic Activities of Ethanol Extract of Seriphidium kurramenses

Sobia Alyas, Nureen Zahra, Ayesha Nisar, Tahir Shafeeq, Muhammad Mansoor Hafeez, Sikandar Hayat, Ayesha Riaz & Beenish Zahid · Journal of Pharmaceutical Research International · 2022

Seriphidium kurramenses traditionally medicinal plant usually not present in Pakistan is used in different biological activities to cure various ailments. However, scare studies are present on S. kurramenses regarding to its medicinal importance to treat fever, inflammation and p...

Open access Research Article 10.9734/jpri/2022/v34i43A36309

GC-MS Analysis of the Bioactive Compounds in Aqueous Ethanol, Dichloromethane, and n-hexane Extracts of Pumpkin (Cucurbita pepo) Seed

C. F. Anyanwu, O. A. Georgewill, U. O. Georgewill & Eric Aigbogun Jr. · Journal of Pharmaceutical Research International · 2022

Aim: The study analysed the bioactive compounds (BACs) present in aqueous ethanol, dichloromethane, and n-hexane extracts of pumpkin (Cucurbita pepo) using Gas chromatography–mass spectrometry (GC-MS) technique. Methodology: The dried grounded seed C. pepo were successively extra...

Open access Research Article 10.9734/jpri/2022/v34i43A36305

Enterobacteriaceae Therapy using Bacteriophages: A Review

C. K. Udomessien, N. E. Okon, C. B. Ubah, V. B. Oti, M. Ioannou & E. A. Ufot · Journal of Pharmaceutical Research International · 2022

Enterobacteriaceae are a family of bacteria, including many familiar pathogens that cause signs of diarrhoea in humans and animals, such as Escherichia coli, Salmonella, Shigella, and Klebsiella. Enterobacteriaceae, the first Gram-negative bacteria, are bacilli (rod-shaped) facul...

Open access Research Article 10.9734/jpri/2022/v34i43A36306

Antimicrobial, Antioxidant, and Anti-inflammatory Evaluation of Synthesised Azo Compounds based on β-naphthol, Catechol and Quinol Nucleus

Claudia Naa Dedei Attoh, Joseph Adu, Cynthia Amaning Danquah, Yakubu Jibira, Patrick Gyan, Emmanuel Bentil Asare Adusei & Cedric Dzidzor Amengor · Journal of Pharmaceutical Research International · 2022

A series of 10-aryl substituted azo dyes were synthesized by coupling of β-naphthol, catechol, and quinol with different aromatic amines. The synthetic compounds were screened for their in vitro antimicrobial, antioxidant, and anti-inflammatory activities. The characterization of...

Open access Research Article 10.9734/jpri/2022/v34i42B36304

Effects of Opioid Sparing Analgesia for Surgical Procedure of Laparoscopic Pyloromyotomy in Order to Enhance Recovery and Better Surgical Outcomes

Muhammad Saleh Khaskheli, Rafia Tabassum, Naseem Mengal, Ali Raza Brohi, Rao Irfan & Munazzah Meraj · Journal of Pharmaceutical Research International · 2022

Aim: To determine the analgesic efficacy in early post operative period with out respiratory depression and to determine surgical outcome for patients under laparoscopic pyloromyotomy. Methodology: This study was done at Pediatric surgery operating theatre and Post anesthesia car...

Open access Research Article 10.9734/jpri/2022/v34i42B36382

Effect of Surface Treatments on Bond Strength of Resin Cements to Titanium: A Literature Review

Reem Ahmed Alzahrani, Ammar Turki Wali, Shaima Fahad Alamri, Ibraheem Talal Bedaiwi & Fetoon Marzoog Alrehaili · Journal of Pharmaceutical Research International · 2022

Objectives: The aims of this literature review are to provide answers to questions on how to improve bonding between titanium and resin cement and how to further implement, in clinical practice, titanium-resin as an alternative to conventional metal–resin systems. Material and Me...

Open access Research Article 10.9734/jpri/2022/v34i42B36303

Clinical Application of Esketamine Hydrochloride in Children with Emergence Agitation under Sevoflurane Anesthesia

Wu Zhaoxia & Wen Xianjie · Journal of Pharmaceutical Research International · 2022

Objective: To investigate the clinical effect of different doses of esketamine in preventing emergence agitation (EA) in children under sevoflurane general anesthesia. Methods: 80 children who underwent elective tonsillectomy or (and) adenoidectomy in our hospital were selected....

Open access Research Article 10.9734/jpri/2022/v34i42B36301

Color Doppler and Ankle-brachial Index in the Diagnosis of Peripheral Artery Disease in Type II Diabetic Subject

Sana Shaikh, Kashaf Anwar, Asma Javed & Zaheda Khatoon · Journal of Pharmaceutical Research International · 2022

Objective: To determine the association of color doppler and ankle-brachial index (ABI) in the diagnosis of peripheral artery disease in type ii diabetic subject. Methods: The study was carried out at ultrasound department of Advanced Radiology Clinic (ARC), Karachi, from January...

Open access Research Article 10.9734/jpri/2022/v34i42B36315

Hypercalcemia and Nephrocalcinosis in an Infant with Subcutaneous Fat Necrosis: A Rare but Potential Serious Clinical Condition

Jennifer N. Nongrum, Anuragsingh Chandel, Smita Jategaonkar & Manish Jain · Journal of Pharmaceutical Research International · 2022

Background: Subcutaneous fat necrosis of the newborn (SCFN) is a panniculitis characterized by the presence of violaceous subcutaneous nodules and indurated plaques on the back, buttocks, proximal extremities, or cheeks. It is a self-limiting benign condition sometimes associated...

Open access Research Article 10.9734/jpri/2022/v34i42B36298

Development and Validation of a UPLC Method for Determination of Mirabegron in Tablet Dosage Forms

B. Anupama, A. Viswanath, . Azizunnisa & Md. Vaseemunnisa · Journal of Pharmaceutical Research International · 2022

Mirabegron is a drug that is used to treat an overactive bladder. Mirabegron activates the β3 adrenergic receptor in the bladder's detrusor muscle, causing muscular relaxation and bladder capacity expansion. A few measurement procedures have been discovered, but they are inconven...

Open access Research Article 10.9734/jpri/2022/v34i42B36299

Prevalence of Oral Screen Appliance Therapy in 6-12 Year Old Children Visiting a University Dental Hospital: A Retrospective Study

Arunn Jaikumarr Ram & Mebin George Mathew · Journal of Pharmaceutical Research International · 2022

The oral screen is a versatile and simple myofunctional instrument that is used to treat dental arc deformities early in the interception. A lip training device was described as an oral screen. Oral screens can be used for people who have bad habits such as mouth breathing, chewi...

Open access Research Article 10.9734/jpri/2022/v34i42B36300

Can Orthopantomogram (OPG) be a Reliable Diagnostic Aid for Mandibular Measurements over Lateral Cephalogram: A Cross-Sectional Study

Shyma Shamnad, Manjusha K. K., Abin Mohammed B. N., Nishad A., Rajesh D., Reyas Y. Rasool & Aparna M. A. · Journal of Pharmaceutical Research International · 2022

Aim: To find the reliability of OPG over Lateral Cephalogram for Mandibular Body Length, Mandibular Ramal Height and Total Mandibular Length. Materials and Methods: Pre-treatment lateral cephalogram and orthopantomogram of 60 patient records within the age group of 12 to 25years...

Open access Research Article 10.9734/jpri/2022/v34i42B36297