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All published articles 7450

Frequency of Anemia in Patients Admitted with Acute Decompensated Heart Failure in Tertiary Care Cardiac Hospital

Sharwan Bhuromal, Faraz Farooq Memon, Muhammad Asim Shaikh & Suresh Kumar · Journal of Pharmaceutical Research International · 2022

Introduction: Anemia is one of the potential comorbid condition in patients with acute decompensated heart failure (ADHF) which is linked to higher morbidity and mortality rates. Worldwide, its prevalence ranges from 4% to >70% in hospitalized patients with ADHF. Unfortunately...

Open access Research Article 10.9734/jpri/2022/v34i39B36245

Novel Technique in Late Stage Avascular Necrosis of Lunate: Tendon Interposition and Ligament Reconstruction with ECRL Tendon– A Case Report

Sarvang Desai, Apurva Patel & Malkesh Shah · Journal of Pharmaceutical Research International · 2022

Aim: To evaluate clinical and functional results of extensor carpi radialis longus tendon ball interposition for treatment of late stage avascular necrosis of lunate (kienbock’s disease). Materials and Methods: Patient with stage 4 kienbock’s disease was treated with excision of...

Open access Research Article 10.9734/jpri/2022/v34i39B36241

Outcomes and Predictors of Non-Responsiveness in Treatment of Naïve and Non-Cirrhotic Patients with HCV Genotype 3 Infection – A Third World Perspective

Saima Mehboob, Noor Mohammad, Amer Abbas & Syed Hassan Danish · Journal of Pharmaceutical Research International · 2022

Objective: To assess the clinical outcome in treatment naïve and non-cirrhotic patients with HCV genotype 3 infection after treatment with Sofosbuvir with declastasvir and valpatasvir (in case of non-responsiveness). Methods: Study included 263 participants. The inclusion criteri...

Open access Research Article 10.9734/jpri/2022/v34i39B36242

A Cross-sectional Comparative Study to Observe the Obstetric Complication Associated with Extreme (35) Maternal Age

Nazia Azam Yousfani, Mehwish Zafar, Faisal Irshad, Rasheed Ahmed Soomro, Azra Ahmed & Fareeda Wagan · Journal of Pharmaceutical Research International · 2022

Aim: To assess the frequency and association of obstetric complications in extreme of maternal ages. Methods: A cross-sectional comparative study was conducted at a tertiary care hospital of district Nawabshah, Sindh and Suleman Roshan Medical College during the period April 2019...

Open access Research Article 10.9734/jpri/2022/v34i39B36239

Analyze and Compare the Pain Level and Complications of Septoplasty with and without Splints and Packing

Muhammad Iqbal Rajput, Gulam Shabir Mahar, Noor Alam Ansari, Muhammad Saleh Khaskhili, Rao Irfan & Munazzah Meraj · Journal of Pharmaceutical Research International · 2022

Aim: The main objective of this study is to analyze and compare the pain level and complications of septoplasty with and without splints and packing. Methodology: Our study comprised of 100 patients who underwent septoplasty procedure both under general and local anesthesia. They...

Open access Research Article 10.9734/jpri/2022/v34i39A36321

Evaluate Functional Outcomes of Postoperative Septoplasty with and Without Splints and Packing

Muhammad Iqbal Rajput, Gulam Shabir Mahar, Noor Alam Ansari, Muhammad Saleh Khaskhili, Rao Irfan & Munazzah Meraj · Journal of Pharmaceutical Research International · 2022

Aim: To evaluate functional outcomes of septoplasty with and without splints and packing. Methodology: This cross sectional study was done at ENT department PUMHSW Nawabshah Pakistan. In this study 100 patients were selected who underwent septoplasty procedure both under local an...

Open access Research Article 10.9734/jpri/2022/v34i39A36325

14-Day Outcome of Treatment Protocol Given to Patients with COVID-19 Admitted in FIC/HDU Karachi

Muhammad Yahya, Saima Ghaus, Kiran Saleem, Baakh Nusrat, Samreena Ishrat & Maira Masaud · Journal of Pharmaceutical Research International · 2022

Aims: To observe outcomes in patients admitted to the High Dependency Unit (HDU) at the Field Isolation Centre Karachi after 14 days of COVID-19 treatment protocol. Patients and meth­ods: This cross-sectional study was conducted at HDU/FIC Karachi at Expo Centre. The duration of...

Open access Research Article 10.9734/jpri/2022/v34i39A36236

Frequency of Hypophosphatemia in Children Presenting with Sepsis in a Tertiary Care Hospital: A Cross-sectional Study

Kashif Habib Qadri, Muhammad Saad Raza, Yousuf Yahya, Suneet Kumar, Rumana Sangi, Aliya Kemal Ahsan & Muhammad Nadeem Chohan · Journal of Pharmaceutical Research International · 2022

  Aim: To determine the frequency of hypophosphatemia in the children presenting with sepsis in a tertiary care hospital. Study Design: A cross-sectional study. Place and Duration: Department of paediatric, civil hospital, Karachi, Pakistan from october 2020 to april 2021. Method...

Open access Research Article 10.9734/jpri/2022/v34i39A36238

Quantitative Determination of the PARP Inhibitor Olaparib (AZD 2281) in Rat Plasma using LC-MS/MS: Application to Pharmacokinetic Studies

Revu Baby Nalanda, Atla Srinivasa Rao, S. Kapileswar & B. Srivani · Journal of Pharmaceutical Research International · 2022

Purpose: Olaparib, a highly selective PARP inhibitor in advanced treatment of ovarian cancer. The method describes a simple, rapid, sensitive, specific LC-ESI-MS/MS assay for the simultaneous detection and accurate measurement of olaparib in rat plasma using telmisartan as an int...

Open access Research Article 10.9734/jpri/2022/v34i39A36232

Effectiveness of Standardized Nursing Care Protocol among Post Cardiac Catheterization Patients to Reduce Hematoma Development

Saeeda Sania, Afshan Nazly, Shamim Siddiqui & . Raja · Journal of Pharmaceutical Research International · 2022

Background: Hematoma development is the most common vascular access complication among post-cardiac catheterization patients. It requires safe and standardized nursing care protocol, as well as qualified and skilled healthcare providers to obtain good outcomes of management. The...

Open access Research Article 10.9734/jpri/2022/v34i39A36234

Frequency of Teenage Pregnancy, Its Associated Risk Factors, Complications and Impact on Fetal Outcome

Nazia Azam Yousfani, Mehwish Zafar, Faisal Irshad, Faiza Syed, Shabnam Aijaz Khowaja & Fareeda Wagan · Journal of Pharmaceutical Research International · 2022

Aim: To determine the frequency of teenage pregnancy with associated risk factors and various complications, and to evaluate the obstetric and fetal outcome. Methods: This cross-sectional study was conducted at the departments of Community Medicine, Pathology and Gynecology &...

Open access Research Article 10.9734/jpri/2022/v34i39A36229

Use the Complete Blood Counts and Esr as Biomarkers Prognostic Tool in Breast Cancer Patients Attending Surgery Department at Esut Teaching Hospital, Parklane Enugu Nigeria

N. Soronnadi Clara, N. C. Ibeh, F. O. Ugwuene, L. Maduka, O. Odurukwe, E. I. Aneke & M. Ajuba · Journal of Pharmaceutical Research International · 2022

Background: Full blood count is a prerequisite investigation requested from all breast cancer patients before and during treatment.Poor parameters adversely influence the outcome of cancers. Objective: This study investigated the use of Complete Blood Count (CBC) and Erythrocyte...

Open access Research Article 10.9734/jpri/2022/v34i39A36230

Formulation and Evaluation of Superporus Hydrogel Composite as a Gastro Retentive Drug Delivery for Cefditoren Pivoxil

D. Jeslin, K. Nithyakalyani, P. Panneerselvam, V. Padmaja, P. Suresh Kumar & S. Anand Kumar · Journal of Pharmaceutical Research International · 2022

The purpose of this work was to incorporate superporus hydrogels for cefditoren pivoxil by using polymer like poly acrylic acid aqua cc polymer and composite agent like cross linked sodium carboxy methyl cellulose in the presence of N,N-methylene-bis-Acrylamide as crosslinking ag...

Open access Research Article 10.9734/jpri/2022/v34i39A36231