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All published articles 7450

A Pilot Study of the Effects of Ajwa Date Seed Extract in a Diabetic Animal with Parallel Observations on Human Subjects

Shifa Felemban & Asmaa Fathi Hamouda · Journal of Pharmaceutical Research International · 2022

Background: most diseases are inequality of the antioxidants, pro-oxidants, and failure in resolved inflammation. Diabetes is a metabolic malfunction associated with inflammation and ends with organs failure. Alternative treatments for diabetes include a lifestyle and an anti-inf...

Open access Research Article 10.9734/jpri/2022/v34i38A36214

Comparative Analysis of Bacteriological Profile of Urine and Stent Culture among Patients with Ureteric Double J Stent

Niaz Soomro, Hira Anis Bumbia, . Abdullah, . Sajan, Atif Javed & Ahmed Fawad · Journal of Pharmaceutical Research International · 2022

  Background: A common indication in urological pathologies and especially in instances of ureteric calculi/obstruction, is the placement of ureteric catheter such as the double J stent. 76% of patient with double J stent may encounter adverse outcome owing to bacterial colonizat...

Open access Research Article 10.9734/jpri/2022/v34i37B36208

Helicobacter Pylori Infection in Paediatric Age Group and Recurrent Abdominal Pain

Maria Khalid, Sadaf Liaqat, Sajid Hussain Sherazi, Rabeya Rehman, Rabia Nisar & Hassan Wajahat · Journal of Pharmaceutical Research International · 2022

  Background: The term ‘recurrent abdominal pain’ or RAP is defined in terms of duration and frequency of pain. The duration is to be defined as: minimum preceding three months, and over this three-month period, minimum3 episodes of pain having severe intensity causing impairment...

Open access Research Article 10.9734/jpri/2022/v34i37B36209

Effect of Immunoglobulin Y Tablets on Streptococcus Mutans Counts in Adolescents: An in vivo Study

Poonam Singla, Abi M. Thomas, Kapil K. Dua & Ruchika Kundra · Journal of Pharmaceutical Research International · 2022

Objectives: Streptococcus mutans has been most intimately associated with the initiation and development of carious lesion. Nowadays, the treatment strategies are aimed at either elimination of this bacterium or suppression of its virulence. The search for more efficient and econ...

Open access Research Article 10.9734/jpri/2022/v34i37B36205

Forced Degradation Behaviour with a Developed and Validated RP-UPLC Method for Estimation Lamivudine and Dolutegravir in Combined Pharmaceutical Dosage Form

Subramaniam Ananda Thangadurai & Dhanabalan Kamalakannan · Journal of Pharmaceutical Research International · 2022

A simple, fast, precise, specific, and accurate reversed phase Ultra Performance Liquid Chromatographic (UPLC) method was developed and validated for the forced degradation studies of the Lamivudine and Dolutegravir in tablet dosage form. Chromatogram was run HSS C18 (2.6 x 50mm,...

Open access Research Article 10.9734/jpri/2022/v34i37B36206

Efficacy of Direct Acting Anti-Viral Agents in Patients Infected with Chronic Hepatitis C Virus: A Single Center Experience

Salman Ahsam, Sanjay Kirshan Kumar, Khadim Hussain Semejo, Ghulamullah Lail, Farina Hanif & Nasir Hassan Luck · Journal of Pharmaceutical Research International · 2022

Background: Hepatitis virus C (HCV) infection is affecting millions of people globally with an estimated prevalence in Pakistan ranging from 4.5 to 8%. Advent of oral direct acting antiviral agents (DAAs) in combination therapy has made possible the treatment of decompensated cir...

Open access Research Article 10.9734/jpri/2022/v34i37B36207

Expertise and Insights of Dentists Perceiving Sign Language

. Rehmatullah, Maham Shah, Khalida Naz, Shanti Chouhan, Shuja Aslam & Asad Tahir · Journal of Pharmaceutical Research International · 2022

Dental consideration to the weak populace is a forthcoming issue in well-being approaches because of the absence of proper and particular techniques. Patients with tangible deficiencies pose the problem to experts in anticipation of oral sicknesses generally because of correspond...

Open access Research Article 10.9734/jpri/2022/v34i37B36202

Parkinson’s Disease: A Review on Ongentys®

Farman Ahmad, Hanfia Manazir, Raghvendra Misra & Anurag Verma · Journal of Pharmaceutical Research International · 2022

Aim: Parkinson’s disease (PD) is an auto neuro-degenerative disease/disorder, mainly affects voluntary movements and behavioral functions in the elderliness. Previous studies narrated various aspects of Parkinson’s disease but they could not explain the Parkinson’s disease along...

Open access Research Article 10.9734/jpri/2022/v34i37B36203

Risk Factors Associated with Overweight and Obesity Occurrence among Female Students

Hassanat Elbashir Mohammed Mustafa · Journal of Pharmaceutical Research International · 2022

Aims: The study was conducted to assess the risk factors leading to the development of obesity among female students to adopt strategies to combat this problem and decrease the risk.  Methodology A cross-sectional study method was conducted among 129 participants at the Universit...

Open access Research Article 10.9734/jpri/2022/v34i37B36204

Medicinal and Health-promoting Properties of Bitter Gourd (Momordica charantia) and Its Extracts

Raza Hussain, Rashida Perveen, Ayesha Murtaza, Xue Huali, Muhammad Sajid Manzoor, Shoaib Younas, Itrat Fatima & Muhammad Naveed Babur · Journal of Pharmaceutical Research International · 2022

Numerous documented researches have been conducted to evaluate the potential of using different plants and herbs as traditional medicines. Bitter gourd (Momordica charantia) is an agricultural commodity belonging to the plant kingdom and family Cucurbitaceae. Besides having a hig...

Open access Research Article 10.9734/jpri/2022/v34i37A36201

A Comparative Study in Hematological Parameters between First Wave Vs Second wave in ICU and non- ICU COVID-19 Patients in India

U. Sunderesh Kamal Chander, M. Vanishree, Sonti Sulochana & E. Yogalakshmi · Journal of Pharmaceutical Research International · 2022

Aim: This study aims to determine similarities and differences in haematological                            parameters between the patients from two waves of severe acute respiratory syndrome coronavirus-2 infection at the time of hospital admission and identify risk biomarkers o...

Open access Research Article 10.9734/jpri/2022/v34i37A36199

Association of Tranexamic Acid with GCS in Patients with Traumatic Brain Injury

Kamil Ziad, Inayat Ali khan, Lal Shehbaz, Santosh Kumar Sidhwani, Bina Fawad & Ariba Fahim · Journal of Pharmaceutical Research International · 2022

Background: Traumatic Brain Injury (TBI) occurs due to head injury ranging from simple blow to penetrating injury. TBI refers to a violently produced brain damage that is either blunting or piercing that accelerates or decelerates, resulting in the development of various clinical...

Open access Research Article 10.9734/jpri/2022/v34i37A36200

Qualitative Expression of Sox2 and Oct4 in Oral Submucous Fibrosis: An Immunohistochemical Study

Rutuja G. Vidhale, Treville Pereira, Megha N. Lalai, A.K. Anjali, Apeksha Jain & Christina Pereira · Journal of Pharmaceutical Research International · 2022

Background: These stemness markers have proved their ability in tumorigenicity, tumor metastasis, and even distant recurrence after chemotherapy in different types of cancer. Also, it has shown its evidence in pre-malignant conditions such as OSMF (Oral Submucous Fibrosis) did sh...

Open access Research Article 10.9734/jpri/2022/v34i37A36197

Association between Raised Serum Lactate Dehydrogenase and Hypertensive Disorders of Pregnancy

Chandra Madhudas, Farkhunda Khursheed, Zakia Zaheen, Ilsa Nadeem, Rabia Wasi & Rashida Akbar · Journal of Pharmaceutical Research International · 2022

Objective: To determine the association between raised serum lactate dehydrogenase (LDH) and hypertensive disorders of pregnancy. Material and Methods: This case control study was conducted in the department of Obstetrics and Gynecology, at Liaquat University of Medical and healt...

Open access Research Article 10.9734/jpri/2022/v34i37A36198

In vitro Inhibition of Dipeptidyl Peptidase-4 (DPP-4) and Arginase by a Dietary Supplement and Its Potential for Improving Quality of Life Factors in Adults

Brett J. West & Fernando Swartz · Journal of Pharmaceutical Research International · 2022

Aim: Somatopause is the progressive and age-related decline of growth hormone (GH) production due to changes in hypothalamic-pituitary axis signaling and results in typical physiological changes associated with the aging process. The purpose of our study was to investigate the an...

Open access Research Article 10.9734/jpri/2022/v34i37A36193