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All published articles 7450

Comparison of Complication Regarding Modified Duhamel Procedure for Hirschsprung’s Disease in Male to Female Children

Masoom Ali Shah · Journal of Pharmaceutical Research International · 2022

Aim: To compare the complications regarding modified Duhamel procedure in male to female children for Hirschsprung’s disease (HSCR). Methodology: This comparative retrospective study was done at pediatric surgery department PUMHSW Nawabshah during Jun 2019-Aug 2020. Sample size w...

Open access Research Article 10.9734/jpri/2022/v34i35A36337

The Dermoscopic Patterns in Common Pigmented Skin Lesions

Sabira Baz Khan, Hafiz Bashir Ahmed, Shazia Bano, Erum Ellahi, Hira Mughal & Hira Shafqaut · Journal of Pharmaceutical Research International · 2022

Objective:  To determine the dermoscopic patterns in common pigmented skin lesions. Setting and duration Study: This study was conducted at Dermatology Department, Civil Hospital, Hyderabad, during October 18, 2020 to April 17, 2021. Materials and Methods: After taking approval f...

Open access Research Article 10.9734/jpri/2022/v34i35A36162

Inhibition of Cell Proliferation by Houttuynia cordata Extract on Gastric Cancer Cells via Induction of Apoptosis

Thanh Quang Nguyen, Hoang Nhat Minh Nguyen, Van Minh Le, Dai-Hung Ngo & Thanh Sang Vo · Journal of Pharmaceutical Research International · 2022

Houttuynia cordata Thunb. is an edible and medicinal plant that belongs to the family of Saururaceae and widely distributes in Eastern Asia countries. H. cordata have been reported as a promising anticancer agent against various cancer cells. This study was to determine anti-prol...

Open access Research Article 10.9734/jpri/2022/v34i35A36163

Knowledge and Practices of Oral Health Status among Pregnant Women Attending Liaquat University Hospital Jamshoro

Ifat Balouch, Erum Jahan, Rehmatullah Kandhro, Zubeda Bhutto, Batool Bibi, Reema Akhtiar & Salman Shams · Journal of Pharmaceutical Research International · 2022

Background: Pregnant women's oral health behaviors and attitudes are infrequently studied in low-income countries, but they should be taken into account when developing preventive or therapeutic research to lessen the load of oral illnesses. Objective: To assess the knowledge and...

Open access Research Article 10.9734/jpri/2022/v34i35A36158

Contemporary Technologies in Chronopharmaceutic Drug Delivery System

Apollo James, Mohanraj Palanisamy, Arun Radhakrishnan & Jasmina Khanam · Journal of Pharmaceutical Research International · 2022

Traditional drug delivery methods aimed for a consistent or sustained medication output to maximize treatment efficacy while minimizing side effects. These dosage forms release medications in a controlled or varied manner. Illnesses are treated by administering drugs to patients...

Open access Research Article 10.9734/jpri/2022/v34i35A36161

Modulation Mechanism of Proanthocyanidins from Leaves of Bayberry (Myrica rubra Sieb. Et Zucc.) on Hyperlipemic Rats Induced by High-fat-diet

Lu-ting Ye, Zong-hua Dong, Jun Liu, Feng Guan & Jian Ge · Journal of Pharmaceutical Research International · 2022

Aim: To investigate the lipid-lowering effect of proanthocyanidins from Bayberry leaf (BLP) in rat model of hyperlipidemia and to clarify the underlying molecular mechanism. Study Design: The study includes in-vitro and in-vivo experiments in rat model. Place and Duration of Stud...

Open access Research Article 10.9734/jpri/2022/v34i35A36159

Analytical Tools Used for Characterization and Development of Minitablets: A Verapamil Hydrochloride Case Study

Bimireddy Bhavani Prasanna Kumar & Rama Rao Nadendla · Journal of Pharmaceutical Research International · 2022

Various analytical techniques were used at different stages of formulation development to assess the interactions and quality throughout the lifecycle of the verapamil hydrochloride minitablets (VHMT). At initial stage of development studies, pre-formulation analytical techniques...

Open access Research Article 10.9734/jpri/2022/v34i35A36160

Proniosomes: Non-Ionic Surfactant Coated Vesicular Carrier Systems with Effective Drug Targeting

Santosh Kumar Rada & Gokula Brijitha · Journal of Pharmaceutical Research International · 2022

Proniosomes is one of the unique drug delivery technology wherein the medicament is enclosed in a vesicle and have a variety of medicinal and cosmetic applications. Vesicular drug delivery reduces the treatment cost by increasing the bioavailability of the drug, especially for sp...

Open access Research Article 10.9734/jpri/2022/v34i34B36150

Effects of Combination of Bi-inject (Triamcinolone and Mitomycin) After Direct Vision Internal Urethrotomy for Short Urethral Strictures

Abdul Rehman, Ahmed Fawad, Atif Javed & Sajjan khan · Journal of Pharmaceutical Research International · 2022

Background: Urethral stricture disease has always been a challenge for urologists. Different treatment modalities that are used for treatment of urethral stricture disease, however recurrence has been a persistent problem. Agents such as triamcinolone and mitomycin-C offer hope b...

Open access Research Article 10.9734/jpri/2022/v34i34B36151

Anterior Inferior Cerebellar Artery Infarct Presenting as Unilateral Deafness in a Young Patient

Krishnan Mohankumar Vignesh, Natrajan Anuradha, Viknesh Prabhu & Patel Harshvardhan Anil Bhai · Journal of Pharmaceutical Research International · 2022

Acute ischemic stroke in the supply of the anterior inferior cerebellar artery is known to be connected with facial weakness, nystagmus, hearing loss, hypalgesia, and ataxia. This is a case of a young man with unilateral deafness caused due to infarction of anterior inferior cere...

Open access Research Article 10.9734/jpri/2022/v34i34B36152

Outcome of Proximal Humerus Fracture

Vinoth Kumar & J. Suresh Kumar · Journal of Pharmaceutical Research International · 2022

Introduction: Proximal fractures of the humerus account for about 4 to 5% of all fractures. They are the most common fractures in elderly population. Treatment of unstable, displaced, and comminuted fractures of the proximal humerus remains challenging. Objectives: The present st...

Open access Research Article 10.9734/jpri/2022/v34i34B36154

Frequency of Complete Heart Block (CHB) and Its Association with Hypertension and Diabetes Mellitus in Patients with Anterior Wall Myocardial Infarction (AWMI)

Mir Fahad Hussain Talpur, Naveed Ahmed Shaikh, Shahbaz Ali Shah, Amjad Ali Hulio, Abdul Salam Detho, Muhammad Faizan, Jawaid Akber Sial & Sajjan Iqbal Memon · Journal of Pharmaceutical Research International · 2022

Background: The presence of conduction defects complicates AMI frequently and is associated with increased short and long term mortality rates. The occurrence of complete heart block in anterior wall myocardial infarction is important because it indicates that infarction is exten...

Open access Research Article 10.9734/jpri/2022/v34i34B36153

A Review on Impurity Profiling, Degradation Studies, and Bioanalytical Methods of Anti-diabetic Drugs

Mahesh M. Deshpande, Madhuri H. Bhalerao & Pooja D. Pabale · Journal of Pharmaceutical Research International · 2022

According to ICH Q3A(R), the impurity in a new drug substance is “any component of a new drug substance that is not the chemical entity defined as a new drug substance”. As Per ICH Q3B(R), the impurity in a new drug product is “any component of the drug product that is not the dr...

Open access Research Article 10.9734/jpri/2022/v34i34B36156

Knowledge and Practices Related to Burn First Aid among General Population in Saudi Arabia

Ezdehar Bakr Fallatah, Aishah Nabil Azam, Faisal Musaad Alhoshan & Turki Faissal Bugshan · Journal of Pharmaceutical Research International · 2022

Background: Burn injuries represent a common type of traumatic injuries. They may cause morbidity, mortality, or psychological and cosmetic problems. About 265 000 individuals die secondary to burns according to the WHO results. Simple first aids following a burn injury have been...

Open access Research Article 10.9734/jpri/2022/v34i34B36155