Inflammation is a vital biological response to injury and infection, but its persistence beyond resolution stages contributes to a range of chronic diseases, including arthritis, asthma and autoimmune disorders. The nuclear factor kappa-light-chain-enhancer of activated B cells (...
Open access
Research Article10.9734/jpri/2025/v37i127790
In recent years, robotic surgical systems have promoted the development of surgical technology due to their advantages such as high-definition surgical vision and flexible surgical arms, and precise operation. The domestic Kangduo Robot® laparoscopic surgical system is a high-pre...
Open access
Research Article10.9734/jpri/2025/v37i127789
Objective: As part of efforts to promote medicinal plants found in the flora of Ivory Coast, this study focused on Khaya grandifoliola C. DC. (Meliaceae : Sapindales). The aim is to conduct a phytochemical study and evaluate the antibacterial activity of the bark of the Khaya gra...
Open access
Research Article10.9734/jpri/2025/v37i127788
The increasing interest in natural remedies for male sexual health has led to the investigation of various plant species with potential aphrodisiac effects. This review examines the comparative effects of Mondia whitei (Omulondo) and Prunus africana on male sexual health. Mondia...
Open access
Research Article10.9734/jpri/2025/v37i127787
Background: Poultry, particularly chickens, are a major source of protein worldwide. However, the overuse of antibiotics in poultry farming has led to the emergence of multidrug-resistant (MDR) bacteria, which can pose serious public health risks. The cloacal region of chickens c...
Open access
Research Article10.9734/jpri/2025/v37i127786
The study of exomoons and exorings represents a growing frontier in exoplanetary science, illuminating planetary formation, system evolution, and the search for habitable environments beyond Earth. Although no confirmed exomoons have yet been identified, advances in transit timin...
Open access
Research Article10.9734/iaarj/2025/v7i1120
Diospyros malabarica, more commonly referred to as the Gaub tree, is known for its ethnomedicine applications, though there is inadequate research regarding its physical capabilities. Herein is described the full study investigating the anticancer, antimicrobial, antisickling and...
Open access
Research Article10.9734/jpri/2025/v37i127784
Aims: Strychnos lenticellata belongs to the family of Loganiaceae. The study was intended to extract the phytochemicals from S. lenticellata using different solvents, the obtained exracts were subjected to determine the antibacterial and antioxidant capacity. Study Design: Dried...
Open access
Research Article10.9734/jpri/2025/v37i127782
Ethylene glycol (EG) is a widely used organic compound found in various consumer products. Due to its accessibility, EG ingestion has led to numerous cases of poisoning. While its effects on the central nervous, cardiopulmonary, and renal systems are well-documented, limited rese...
Open access
Research Article10.9734/jpri/2025/v37i127783
Aim: The present study aims to formulate and evaluate α-arbutin–based hydrogel patches for periorbital depigmentation and management of under-eye dark circles. Place and Duration of Study: HSK college of pharmacy, Bagalkote. Methodology: Hydrogel patches were prepared using Agar/...
Open access
Research Article10.9734/jpri/2025/v37i127781
Background: Emblica officinalis (amla) is known for its vitamin C-rich fruit, but its root remains underexplored. Ascorbic acid (vitamin C) is a vital plant antioxidant that plays essential roles in stress responses. We investigated E. officinalis root as a potential source of vi...
Open access
Research Article10.9734/jpri/2025/v37i127780
Scope and Objective: Metered-dose inhalers (MDIs) remain the cornerstone of inhalation therapy for asthma and chronic obstructive pulmonary disease (COPD), offering a portable, efficient, and cost-effective means of delivering drugs directly to the lungs. The global MDI market is...
Open access
Research Article10.9734/jpri/2025/v37i127778
Background: Manufactured chemicals are the second important classes as the natural chemicals mentioned above and the American Chemistry Council (ACC) projects global chemical production to rise by 3.4 % in 2024 and 3.5 % in 2025, after increasing just 0.3 % in 2023. Exist a varie...
Open access
Research Article10.9734/jpri/2025/v37i127777
Issouf Fofana, Aboubakar Traoré, Bafétigué Ouattara, Akassa Marius Bernard Djako, N'goran Urbain Florent Niangoran, Souleymane Konate & Eugene Megnassan·Journal of Pharmaceutical Research International·2025
Alzheimer's disease (AD) accounts for 60 to 70% of dementias worldwide. This condition is primarily associated with the decrease in acetylcholine (ACh) levels, due to the action of human acetylcholinesterase (AChE). The lack of a curative treatment for Alzheimer's disease undersc...
Open access
Research Article10.9734/jpri/2025/v37i127776
Bedoor Turky, Basmah Alotaibi, Aryam H. Alzahrani, Maryam H. Khan, Ghala M. Althubaiti, Khalid Adel, Shahad AlFaisal, Aljazy Alhasson, Nouf Alhathloul, Lama A. Albishri, Danah A. Alsharif, Hind Alrshidi, Fatimah Mslam, Lara M. Samhan & Baraa Alghalayini·Journal of Pharmaceutical Research International·2025
Alopecia areata (AA) is an autoimmune disorder characterised by patchy hair loss and a significant psychological impact. Although traditionally attributed to Th1-mediated pathways, emerging evidence highlights roles for Th2, Th9, and IL-23 signalling. This study aims to perform a...
Open access
Research Article10.9734/jpri/2025/v37i127775