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Carcinogenic Potential of E-cigarettes: Vapor Profile and Cellular Effects

Amy Hutchinson & Marwan ElBagoury · Journal of Pharmaceutical Research International · 2022

E-cigarettes are devices that vaporize a liquid made of polyglycerol, glycol, flavorings, and nicotine, for inhalation. Initially created for smoking cessation, the health risks of these devices are still not clear. This literature review compiles data on the chemical profile of...

Open access Research Article 10.9734/jpri/2022/v34i28B36039

Prevalence of Leukoplakia among Patients Visiting a Private Dental Hospital- An Institutional Study

K. Ashwini & Reshma Poothakulath Krishnan · Journal of Pharmaceutical Research International · 2022

Background: The oral ‌mucous‌ ‌membrane‌ ‌is‌ ‌an‌ ‌integral‌ ‌part‌ ‌of‌ ‌the‌ ‌oral‌ ‌cavity‌ and oral‌ ‌premalignancy‌ plays an ‌intermediate‌ ‌stage. Oral‌ ‌leukoplakia‌ ‌otherwise‌ ‌called‌ ‌smoker’s‌ ‌keratosis‌ ‌is‌ ‌a‌ ‌potential‌ ‌premalignant‌ ‌disorder‌ and if not diag...

Open access Research Article 10.9734/jpri/2022/v34i28B36040

Concept and Therapeutic Approach of Intermediate Hyperglycemia with Special Reference to Unani Medicine

Abdul Nasir & Gazala Fatma · Journal of Pharmaceutical Research International · 2022

Intermediate Hyperglycemia is a category of glucose tolerance representing an intermediate stage between normal glucose tolerance (NGT) and diabetes. Within this category are two subcategories: impaired fasting glucose (IFG; 100 –125 mg/dl) and impaired glucose tolerance (IGT; de...

Open access Research Article 10.9734/jpri/2022/v34i29A36041

Fine Needle Aspiration Cytology: A Reliabe Diagnostic Approach in Supraclavicular Lymph Node Swelling: A Study at Pumhs-W, Nawabshah, Sind, Pakistan

Sikandar-e-Azam Yousfani, Saifullah Brohi, Shazia Bano, Nazia Azam Yousfani, Ashok Kumar & Moin Ul Islam Shah · Journal of Pharmaceutical Research International · 2022

Objective: This study was conducted with the aim to approach the diagnostic accuracy of fine needle aspiration cytology in supraclavicular lymph node swelling at outpatient department. Methods: The study is cross-sectional, descriptive conducted at General Surgery department Unit...

Open access Research Article 10.9734/jpri/2022/v34i29A36042

Development and Validation of an HPLC-MS/MS Method for the Determination of Remdesivir in Rat Plasma

Naidu Srinivasa Rao, Anilkumar Adimulapu, B. Nagendra Babu & G. Rambabu · Journal of Pharmaceutical Research International · 2022

Background: Remdesivir is an excellent drug for the medication of covid-19.So; it is an interesting method to develop a novel and reliable HPLC-MS strategy for establishment of  Remdesivir. Objective: To develop a new rapid and sensitive HPLC-MS/MS method for the estimation of Re...

Open access Research Article 10.9734/jpri/2022/v34i28B36032

Assessment of RBC Folate and Serum Vitamin B12 Levels in Pakistani Women of Reproductive Age Group: An Approach towards Prevention of Adverse Pregnancy Outcomes

Iram Nazir, Maeesa Wadood, Sadia Nazir, Muhammad Rizwan, Muhammad Adil Ayub & Syeda Shabana Nasir · Journal of Pharmaceutical Research International · 2022

Background: Folate and Vitamin B12 are important micronutrients necessary for fetal growth and development. Deficiencies of these vitamins in women of reproductive age results in adverse pregnancy outcome. Objective: To determine red blood cell folate and serum Vitamin B12 levels...

Open access Research Article 10.9734/jpri/2022/v34i28B36033

Impact of Aerobic and Anaerobic Field Tests on Physical Fitness of Female Athletes

Sumera Sattar, Yasmeen Iqbal & Shahzaman Khan · Journal of Pharmaceutical Research International · 2022

Success in sports and many other group activities requires a total feeling of well-being as well as specialized and strategic skills in individual and team activities. One of the fundamental characteristics that influence athletic performance is viewed as PF. The main objective o...

Open access Research Article 10.9734/jpri/2022/v34i28B36034

Quantification of Impurity-G Content in Levetiracetam Injection (100 mg/ml) by Using RP-HPLC Technique

Syed Mastan Ali, Ponnuri Bharath, V. Siva Ramakrishna & D. Ramachandran · Journal of Pharmaceutical Research International · 2022

Extremely responsive technique for the quantification of impurity-G content in Levetiracetam samples by RP-HPLC method has been presented in the here manuscript. Quantification of impurity-G content in Levetiracetam sample by HPLC with UV Detector. Impurity-G was concluded by RP-...

Open access Research Article 10.9734/jpri/2022/v34i28B36035

Frequency of Common Congenital Anomalies among Neonates in Tertiary Care Hospital: A Cross-sectional Study

Noor Ul Ain Shaikh, Abdul Hamid Shaikh, Iqra Rafique Khokhar, Sobia Larik, Abdul Rehman Shaikh & Muhammad Nadeem Chohan · Journal of Pharmaceutical Research International · 2022

Aim: To determine the frequency of common congenital anomalies among neonates in tertiary care hospital Study Design: A cross-sectional study. Place and Duration: Children Hospital Larkana Pakistan from April to October 2018. Methodology: One hundred twenty-four newborns with con...

Open access Research Article 10.9734/jpri/2022/v34i28B36028

Antiepileptic Activity of Indian Filbert Fruit Extract in Experimental Animal Models

Jennifer Fernandes, S. Anusha & K. Vijay Bhaskar · Journal of Pharmaceutical Research International · 2022

Aim: To screen the antiepileptic activity of ethanolic fruit extract of Indian filbert. Methodology: The cleaned, dried and powdered fruits of Indian filbert were subjected to extraction.Preliminary Phytochemical studies were carried out for the presence secondary metabolites.Acu...

Open access Research Article 10.9734/jpri/2022/v34i28B36029

Perceptions of Parents about Online Learning and Physical Activities of their Children during the COVID-19 Pandemic

Qurratulain Rehan, Maria Shiraz, Mazna Toosy, Shahzaman Khan, Shahzada Qaisar, Alamgir khan & Muhammad Zafar Iqbal Butt · Journal of Pharmaceutical Research International · 2022

The present study aimed to assess the perceptions of parents about online learning and physical activity of their children. A qualitative study was undertaken to determine the perceptions of parents about online learning during COVID-19 to get a deep insight into real-life experi...

Open access Research Article 10.9734/jpri/2022/v34i28B36030

Evaluating Teaching and Learning Modalities in Higher Education: The Case of BAMS Students

Swapnil Borage, Bharat Rathi, Priyanka Shelotkar & Suvarna Dangore · Journal of Pharmaceutical Research International · 2022

Background: During the COVID-19 pandemic, institutions were obliged to change the teaching methods, as conventional teaching methods were not adoptable for the legislations of COVID-19 protocols. Students in large number started enrolling in the online courses. The reviews about...

Open access Research Article 10.9734/jpri/2022/v34i28A36025

Effect of Polymorphisms in Drug Transporters on Cisplatin Efficacy and Nephrotoxicity in Paediatric Osteosarcoma

Samaa Ramadan, Ahmed Nabil, Hadeer Ghonim, Asmaa Salama, Enas EL Nadi & Rania M. Labib · Journal of Pharmaceutical Research International · 2022

Introduction: Osteosarcoma (OS) is the most common type of primary bone tumor in children and adolescents. Chemotherapeutic resistance to cisplatin represents such a significant barrier in the successful treatment of Osteosarcoma. The degree of nephrotoxicity and drug resistance...

Open access Research Article 10.9734/jpri/2022/v34i28A36026

Nafamostat Mesylate in the Prevention of Post-endoscopic Retrograde Cholangiography Pancreatitis: A Meta-analysis

Hyder Osman Mirghani, Abdelwahab Hassan Abdelwahab Hussien & Abdullah Suliman Al Atawi · Journal of Pharmaceutical Research International · 2022

Previous evidence from observational studies showed that Nafamostat mesylate (NM) was effective in post-ERCP pancreatitis prevention. We aimed to assess full-text prospective studies on the role of NM in post-ERCP pancreatitis prevention. We searched the PubMed, Medline, and Goog...

Open access Research Article 10.9734/jpri/2022/v34i28A36021