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Facile and Green Synthesis of Carboxy Methyl Cellulose Stabilized Bio-Functionalized Gold Nanoparticles and Its Catalytic Activity

K. V. Padmavathi, M. Padma & Nowduri Annapurna · Journal of Pharmaceutical Research International · 2022

Gold nanoparticles (AuNP’s)are synthesized in sustainable green method using Carboxy Methyl Cellulose (CMC) and employed as catalyst in the reduction of p-nitro aniline with NaBH4 to p-phenylene diamine. It is observed that the speed of reaction was fast due to their size, as par...

Open access Research Article 10.9734/jpri/2022/v34i28A36023

Updates in Different Types of Keratitis: A Review

Zafar Iqbal, Wael Salamah Thiyab Alanazi, Talal Ahmed A. Albalawi, Abdulmajed Mohammad A. Alrawaili & Abdulaziz Salamah T. Alanazi · Journal of Pharmaceutical Research International · 2022

Keratitis is the medical term for corneal irritation. The cornea is the front of the eye's dome-shaped opening. The iris and pupil of a person's eye can be seen through the cornea, which is usually clear. It is not difficult to diagnose keratitis; however, determining the cause i...

Open access Research Article 10.9734/jpri/2022/v34i28A36016

Management of a Large Periapical Lesion Following Nonsurgical Retreatment and Low-level Laser Therapy: A Case Report

Soheila Darmiani · Journal of Pharmaceutical Research International · 2022

Tissue repair is an essential process that reestablishes tissue integrity and regular function. Nevertheless, different therapeutic factors and clinical conditions may interfere in this process of periapical healing. Long-term success of root canal treatment(RCT) is dependent on...

Open access Research Article 10.9734/jpri/2022/v34i28A36019

The Economic Burden of Antibiotic Resistance Based on Anti-microbial Susceptibility Tests in Various Infections in a Tertiary Care Hospital: A Prospective Study

M. A. Lavanya, Khadeeja Nizamudeen, Parvathy J. S., Dhanya Dharman & Shaiju. S. Dharan · Journal of Pharmaceutical Research International · 2022

Introduction: Antibiotics are anti-microbial agents used for the treatment of various bacterial infections. Excessive use, inappropriate prescription pattern conduct to antibiotic resistance (AR). Antibiotic resistance leads to an increase in the cost of medical care. Our study a...

Open access Research Article 10.9734/jpri/2022/v34i28A36017

Application of Chemically and Physically Synthesized Metal Nanoparticles to Staphylococcus aureus

Mohammed Ali Alshehri · Journal of Pharmaceutical Research International · 2022

The infections caused by S. aureus have emerged as a grave challenge to human health worldwide. Further, conventional antibiotic therapies for S. aureus-mediated infections are gradually becoming ineffective due to the emergence of drug-resistant strains like methicillin-resistan...

Open access Research Article 10.9734/jpri/2022/v34i28A36020

Phytochemical Analysis and Antioxidant Activity of Avocado Pear Peel (Persea americana) Extract

C. Umerie Sunday, H. Okorie Ndidiamaka, D. Dike Ugochukwu & I. Ani Njideka · Journal of Pharmaceutical Research International · 2022

This study evaluated the phytochemicals and antioxidant activity in Persea americana peel it also assessed the efficiency of Persea americana peel (Avocado Pear fruit peel) waste in different in vitro activities in order to explore the possibility of utilizing waste as a value-ad...

Open access Research Article 10.9734/jpri/2022/v34i28A36018

Transferosomes: Vesicular Carrier for both Hydrophilic and Lipophilic Drugs

R. Santosh Kumar & Maharnab Pradhan · Journal of Pharmaceutical Research International · 2022

The vesicular system has accessed significant importance towards a sustained drug delivery system in recent years. This article was designed to review the future of vesicular systems known as transferosomes. The vesicles are softer and highly deformable than liposomes. The word T...

Open access Research Article 10.9734/jpri/2022/v34i27B36013

Level of Mediations on Pain and Satisfaction Level of Patients Undergoing Abdominal Surgery

Ayesha Javaid, Mah Gull & Iqra Tasleem · Journal of Pharmaceutical Research International · 2022

The main objective of the study was to analyse the level of mediations on pain and satisfaction level of patients undergoing abdominal surgery. This cross sectional study was conducted at Fatima Jinnah Medical University Lahore. The study was performed with 124 patients undergoin...

Open access Research Article 10.9734/jpri/2022/v34i28A36015

Nanotherapeutic Drug Synthesized by Way of a Microbial Pathway Targeting Staphylococcus aureus

Ziaullah M. Sain · Journal of Pharmaceutical Research International · 2022

Staphylococcus aureus (S. aureus) is one of the most common human pathogens causing various infectious diseases. Further, its ability to form biofilm and the emergence of antibiotic resistance strains has made it difficult to treat the infection. A nanoparticle-based therapeutic...

Open access Research Article 10.9734/jpri/2022/v34i27B36008

Design, Synthesis of Mannich Bases Derivatives of Thiosemicarbazide and their Evaluation for Anticancer Activity using Potato Disk Bioassay Method

Geetanjali Sandip Patil & Sachin Ashok Pishawikar · Journal of Pharmaceutical Research International · 2022

Mannich bases and thiosemicarbazide individually are known to show verity of pharmacological activities such as anti-inflammatory, anticancer, antifilarial, antibacterial, antifungal, anticonvulsant, anthelmintic, antitubercular, analgesic, anti-HIV, antimalarial, antipsychotic,...

Open access Research Article 10.9734/jpri/2022/v34i27B36007

A Review on the Therapeutic Management of COVID-19 Associated with Thrombotic Events and Coagulopathies

R. Vigneswaran, S. R. Senthil Kumar, T. Venkatachalam, P. Kalaiselvi, K. Sattanathan, R. Rajaguru & N. Srinivasan · Journal of Pharmaceutical Research International · 2022

Severe acute respiratory syndrome coronavirus two (SARS-CoV-2) is answerable for the coronavirus illness in 2019 (COVID-19) that chop-chop evolved from a virus in metropolis, Varied coagulopathies are rumored in association with COVID-19, together with disseminated intavasular ac...

Open access Research Article 10.9734/jpri/2022/v34i27B36010

Recent Advancements in Gibberellic Acid Formulation Techniques and Economics of Use in Agriculture

Avinash Tupe, Atul Baravkar & Ganesh Devkate · Journal of Pharmaceutical Research International · 2022

Gibberellins comprises of a broader family of plant advancement hormones found during the 1930s, which are synthesized by implies of the terpenes course from the geranylgeranyl diphosphate and incorporate a crucial structure formed by an ent-gibberellane tetracyclic skeleton. Amo...

Open access Research Article 10.9734/jpri/2022/v34i27B36005

Updates in Causes, Risk Factors, Diagnosis and Management of Lichen Planus

Samiah Abdulrahman Abanomy, Abdulaziz Saqer A. Alanazi, Jehad Ahmed Alabdulminaim, Laila Shuqayr Alrashidi & Maram Nasser Alawlah · Journal of Pharmaceutical Research International · 2022

Bhutani et al. originally described a pigmented variety of lichen planus (LP) from India in 1974, and created the label LP pigmentosus (LPP) to better describe it. LPP is one of several variations of the LP gene. This skin lesion has also been reported in the Middle East, Latin A...

Open access Research Article 10.9734/jpri/2022/v34i27B36006

Assess the Mean Change in Outcomes of Sildenafil in the Treatment of Lower Urinary Tract Symptoms and Erectile Dysfunction Due to Benign Prostatic Hyperplasia

Arif Ali, Shahid Hussain, Bilal Suria, Safiullah Sohu, . Murtaza & Suhail Dilawar · Journal of Pharmaceutical Research International · 2022

Objective: To assess the mean change in outcomes of sildenafil in the treatment of lower urinary tract symptoms and erectile dysfunction due to benign prostatic hyperplasia. Study Design: This is a quasi experimental study. Setting: The study was carried out at OPD of Department...

Open access Research Article 10.9734/jpri/2022/v34i27B36002