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All published articles 7450

Effect of Zhixue Mingmu Formula on Retinal Vasopermeability of Streptozotocin-Induced Diabetic Retinopathy in Rats

Xin Jia, Yue Zhang, Minglian Zhang, Zanzhang Yang, Yinglin Liu, Chengquan Li & Mingran Li · Journal of Pharmaceutical Research International · 2022

Aims: To investigate the efficacy of Zhixue Mingmu Formula (ZXMM), a traditional Chinese herbal compound, for retinal vasopermeability in streptozotocin (STZ)-induced diabetic retinopathy (DR) in rats. Materials and Methods: This experimental study was performed at the Hebei Prov...

Open access Research Article 10.9734/jpri/2022/v34i21A35841

Frequency of Celiac Disease in Type 1 Diabetic Children Presenting at Tertiary Care People Medical College Hospital Nawabshah Pakistan

Ameer Ali Jamali, Azizullah Langah, Naseer Ahmed Memon, Badarudin Almani, Safdar Ali Jamali, Attiya Ayaz, Durga Devi & Arslan Ahmer · Journal of Pharmaceutical Research International · 2022

Objective: The goal of this research has been to find out how common celiac disease is in type 1 children with type 1 diabetes who visit multispecialty hospitals. Methodology: This was a cross-sectional research. This study was directed at Pediatric Medicine Department, Mother an...

Open access Research Article 10.9734/jpri/2022/v34i21B35842

Wearable Devices and mHealth: The Significant Applications in COVID 19 Pandemic

Ganesh Choudhari, Prajakta Wagh, Vishnu Choudhari, Ashwini Gawade, Ranjit Gadhave & Chandrashekhar Bobade · Journal of Pharmaceutical Research International · 2022

Wearable devices (WDs) and mHealth (Mobile Health) give you the healthcare services, overcoming geographical, temporal or even organizational obstacles. Wearable technologies will have non-encroaching and sovereign devices that collect save and examine physiological information t...

Open access Research Article 10.9734/jpri/2022/v34i21B35843

Protocol on Effects of Breast Caps on Breast Engorgement among Postnatal Mother

Anita K. Kale & Vaishali Taksande · Journal of Pharmaceutical Research International · 2022

Breast  Engorgement  is  defined  as  the  physiologic  process  of body  in  postnatal  mothers following birth, having sign and symptoms of painful swelling of the breast combine with sudden increase in milk volume. Resulting in Lymphatic and vascular blockage or obstruction an...

Open access Research Article 10.9734/jpri/2022/v34i21B35844

Lactate Dehydrogenase Enzyme Level in Women with Severe Preeclampsia: A Cross-sectional Study

Nadia Hameed, Yasmeen Bibi, Shehreen Memon, Sanam Channa, Muhammad Ali Memon & Muhammad Nadeem Chohan · Journal of Pharmaceutical Research International · 2022

Aim: To determine the frequency of raised lactate dehydrogenase enzyme in women with severe preeclampsia. Study Design: Cross-sectional study. Place and Duration: Obstetrics and Gynecology department at Liaquat University Hospital Hyderabad from June 2018 to December 2018. Method...

Open access Research Article 10.9734/jpri/2022/v34i21B35845

Homocysteine Levels in Acute Ischemic Stroke

Eram Pathan, Ashok Kumar Lohano, Muhammad Saleem Rind, Anwar Ali Jamali, Attiya Ayaz, Durga Devi & Arslan Ahmer · Journal of Pharmaceutical Research International · 2022

Objective: The objective of this study was to determine the frequency of elevated homocysteine levels in acute ischemic stroke patients presenting to the medical department, civil hospital, Nawabshah. Methodology: A cross-sectional study was conducted at the Department of Medicin...

Open access Research Article 10.9734/jpri/2022/v34i21B35846

An Ultra Performance Liquid Chromatography-PDA Method for the Determination of a Novel Antipsychotic-Blonanserin in Bulk and its Tablet Dosage Form

Aditi Pal, Suman Acharyya & Samiran Sadhukhan · Journal of Pharmaceutical Research International · 2022

To develop a new ultra-high-resolution liquid chromatographic technique for determining Blonanserin concentrations in APIs and tablets. A DIKMA Endoversil (2.1 x 50mm, 1.7µm) column with a flow rate of 0.4 mL/min and an eluent measured at 237 nm was used for the chromate-graphic...

Open access Research Article 10.9734/jpri/2022/v34i21B35847

Recent Approaches of Drugs and Vaccines Used in COVID 19: A Review

S. Sivakumar, K. Kathiresan & P. Pandian · Journal of Pharmaceutical Research International · 2022

A novel SARS-CoV-2 coronavirus developed in December 2019, triggering a life-threatening pneumonia outbreak in China, and has since expanded worldwide, producing a pandemic. Because of the urgent need to control the disease and the dearth of specific and effective treatment optio...

Open access Research Article 10.9734/jpri/2022/v34i22A35848

Is Decline Possible in Congenital Heart Defects by Adjusting Avoidable Risk Factors?

Pushpa Goswami, Waseemullah Sheikh, Farhana Rajpar, Nayab Qazi, Bibi Rabia & Fahmida Gul · Journal of Pharmaceutical Research International · 2022

Introduction: Congenital heart defects (CHD) are the leading causes of birth defects-associated morbidity and mortality with incidence variable with geographic locale, race, family history and gender of the baby. Material and Methods: This descriptive study was conducted on 96 in...

Open access Research Article 10.9734/jpri/2022/v34i22A35849

Influence of Different Parenting Styles on Dentist’s Treatment Plan

Ivan Obadiah & E. M. G. Subramanian · Journal of Pharmaceutical Research International · 2022

Every paediatric dentist desires to treat their patients in a stress and anxiety free environment. All steps including diagnosis of the condition, explaining the existing dental status to the patient and treatment planning are based on the mental attitude of the patient and how t...

Open access Research Article 10.9734/jpri/2022/v34i22A35851

Basal Cell Carcinoma: In Tertiary Care Center, Demographic Details and Histological Subtypes at Pumhs-W Nawabshah, Pakistan

Shazia Bano, Kousar Parveen, Hafiz Bashir Ahmed, Hina Sabeen, . Sikander-e-Azam & Nazia Azam Yousufani · Journal of Pharmaceutical Research International · 2022

Background: Skin malignancies are more common in fair-skinned persons, but their increasing incidence is alarming in our population. Objective: To evaluate the Basal Cell Carcinoma (BCC) in a tertiary care center, in terms of frequency, age, sex, sites, and histological subtypes....

Open access Research Article 10.9734/jpri/2022/v34i22A35850

Down Regulation in Glutathione S-Transferase Stimulate Oxidative Stress and Genetic Susceptibility of Human Breast Cancer

Asia Adil, Mahrukh Malik, Javeria Arshad Malik, Sara Nazir & Irum Sabir Ali · Journal of Pharmaceutical Research International · 2022

Glutathione S-Transferase is an enzyme that catalyzed the formation of thio-ether conjugates between the endogenous tripeptide glutathione and xenobiotic compounds. Imbalance of glutathione level is observed in a variety of disease including breast cancer. In the present study we...

Open access Research Article 10.9734/jpri/2022/v34i20B35827

A Comprehensive Review of a New Nanosuspension for Improving the Oral Bioavailability of Poorly Soluble Drugs

G. Karthick, D. Akiladevi & M. Irfan Ahamed · Journal of Pharmaceutical Research International · 2022

Nanosuspension is a novel drug formulation for the delivery of hydrophobic drugs. The problem of medications that are poorly water-soluble and have low bioavailability is countered by nanosuspension technology. Solubility is a significant physiochemical element that influences dr...

Open access Research Article 10.9734/jpri/2022/v34i20B35828

Bisphosphonate Induced Osteonecrosis of the Jaw in Renal Sarciodosis: A Case Report

N. S. Mamatha, J. K. Savitha, R. Narahari & Monisha Uday Hangal · Journal of Pharmaceutical Research International · 2022

The therapeutic use of Bisphosphonates has increased in the last decade. The long-term use of bisphosphonates has led to a challenging complication related to jaws knows as Bisphosphonate- induced osteoradionecrosis of the jaw BIONJ. In this paper we report a case of BIONJ in a...

Open access Research Article 10.9734/jpri/2022/v34i20B35831

Validated RP-HPLC Method Development for Estimation of Ertugliflozin and Sitagliptin in Bulk and Dosage Forms

B. Rajeswari, N. Saritha & N. Devanna · Journal of Pharmaceutical Research International · 2022

A simple, accurate, precise method was developed for the simultaneous estimation of the Ertugliflozin and Sitagliptin in bulk and tablet dosage form. Chromatogram was run through Std Discovery C18150 x 4.6 mm, 5m. Mobile phase containing Buffer 0.1% OPA (2.2ph): Acetonitrile take...

Open access Research Article 10.9734/jpri/2022/v34i20B35829