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All published articles 7450

Phytochemical Profiling and Pharmacognostic Evaluation of Oldenlandia corymbosa and Ocimum sanctum Leaves Hydroalcoholic Extracts: Comparative Study

Shaktijit Das, Pranabesh Ghosh, Chandreyi Ghosh, Moumita Saha, Alok K. Hazra & Sirshendu Chatterjee · Journal of Pharmaceutical Research International · 2022

Herbs are an important source of bioactive substances. These are widely used to treat several disorders for better function in the human body, minimum toxic effects, and widespread availability. A total of two medicinal herbs from West Bengal, India, such as Oldenlandia corymbosa...

Open access Research Article 10.9734/jpri/2022/v34i17A35747

Evidence of Risk Factors Associated with Autosomal Dominant Polycystic Kidney Disease in Newly Diagnosed Adult Hypertensive Patients in NAUTH Nnewi, Nigeria

Nkiruka R. Ukibe, Anya O. Kalu, Isaac P. Emeje, Solomon N. Ukibe, Gloria E. Ukibe & Chigozie C. Obiekezie · Journal of Pharmaceutical Research International · 2022

Aims & objectives: Due to other chronic diseases that are associated with hypertension and kidney disease, little or no attention has been paid to the existence of polycystic kidney disease in Nigeria. The present study aimed at assessing the prevalence of some risk factors o...

Open access Research Article 10.9734/jpri/2022/v34i16B35745

Use of Systemic Doxycycline as An Adjunct to Initial Periodontal Therapy in Mild to Moderate Generalized Periodontitis: A Randomized Clinical Trial

Hakam Rabi & Mohammad Assaf · Journal of Pharmaceutical Research International · 2022

Background: Antibiotics like doxycycline can show an anti-bacterial effect which can reduce the bacterial load and promote healing in patients with chronic periodontitis. Aim: To evaluate the use of doxycycline as an adjunct to initial periodontal therapy in mild to moderate peri...

Open access Research Article 10.9734/jpri/2022/v34i16B35748

Assessment of the Level of Awareness among Parents about Avertive Measures and its Relationship with Dental Health Status of 6–12 Years Old Children in Hazaribag, Jharkhand, India

Swati Singh, Nudrat Neyaz, Alok Vrat Singh, Aditi Singh Tanwar & Krishna Beni · Journal of Pharmaceutical Research International · 2022

Background: A child's oral health is critical to his or her general health as well as well-being, and it is one of the foundations for a disease-free life. Because a parent or caregiver plays such a significant part in a child's life, their understanding together with attitude to...

Open access Research Article 10.9734/jpri/2022/v34i16A35728

Implant-Supported Hybrid Prosthesis using All on Six Concept for Atrophic Ridges with Severe Gag Reflex: A Case Report

Anamika Ahlawat, Manu Rathee, S. Divakar, Sandeep Singh, Sujata Chahal & Poonam Wakure · Journal of Pharmaceutical Research International · 2022

Aims: Edentulism is correlated to poor self-esteem and depression in both young and old individuals due to social rejection. For edentulous patients who are not interested in removable prosthesis, implant-supported fixed prosthesis might be an appropriate treatment modality. The...

Open access Research Article 10.9734/jpri/2022/v34i16A35775

Academic Resilience of Healthcare Professional Students in Pakistan: Need of the Hour

Madeeha Malik, Umme Salma, Azhar Hussain & Shazana Rana · Journal of Pharmaceutical Research International · 2022

Introduction: Due to the challenging and competitive academic environment throughout the world, the mental health of students enrolled in healthcare professions is largely affected resulting in burnout and poor quality of life. Lack of academic counseling and poor teaching strate...

Open access Research Article 10.9734/jpri/2022/v34i16A35730

Role of Protein C, Protein S and Antithrombin III Levels in High-risk Pregnant Women in Karachi's Gadap Region for Obstetric Complications

Muhammad Rizwan, Syeda Shabana Nasir, Irshad Ahmed Ansari, Uzma Afreen, Nasima Iqbal & Syed Fazal-e-Karim Faisal · Journal of Pharmaceutical Research International · 2022

Objectives: Thrombophilia has been connected to both pregnancy difficulties and recurrent miscarriage. The purpose of this project is to establish a baseline of protein C, protein S, and AT III levels in pregnant females with various pregnancy-related problems, assess the prevale...

Open access Research Article 10.9734/jpri/2022/v34i16A35731

Frequency of Different Histological Types of Breast Tumors Reported at DHQ Hospital Abbottabad Pakistan

Attiya Ayaz, Taj Muhammad, Kishwar Ammir, Rukia Farzana, Gulshan Ali Memon, Farzana Mallah & Arslan Ahmer · Journal of Pharmaceutical Research International · 2022

Introduction: The carcinoma of Breast is the most common form of cancer and thus the major source of carcinoma mortality globally. Objective: The goal of this study was to determine the most prevalent etiology of a fresh breast tumor as well as the occurrence of different types i...

Open access Research Article 10.9734/jpri/2022/v34i16A35732

Surgical Apgar Score: Utility in Predicting Postoperative Outcome in Cases of Exploratory Laparotomy

Nimesh Srivastava & M. B. Bagawan · Journal of Pharmaceutical Research International · 2022

Aims and Objective: The aim of this study is to correlate SURGICAL APGAR score in predicting post-operative mortality and morbidity. Materials and Method: This was a prospective study. All patients fulfilling the inclusion criteria in Krishna institute of medical sciences karad w...

Open access Research Article 10.9734/jpri/2022/v34i16A35733

Elucidation and Prediction of Molecular Mechanisms and Associated Pathways of the Prostaglandin-endoperoxide Synthase-2 as a Common Key Gene for Diabetes and Cachexia: Bioinformatics Strategies

Amir Saeed · Journal of Pharmaceutical Research International · 2022

Cachexia and diabetes both feature severe weight loss as a phenotype, and both diseases share several gene and protein abnormalities. This study investigates the PTGS2 gene as a common key gene for diabetes and cachexia. A variety of biological databases and enrichment approaches...

Open access Research Article 10.9734/jpri/2022/v34i16A35776

Electro-coagulation of Bio-treated Pharmaceutical Wastewater for RO Pretreatment

J. K. Samson Ponselvan & A. G. Murugesan · Journal of Pharmaceutical Research International · 2022

Background: The advanced wastewater and water treatment by Reverse Osmosis (RO) system have almost become a common treatment option in industries. However, achieving a consistent RO feed water quality and the rigor of RO pre-treatment pose a big challenge for water treatment spec...

Open access Research Article 10.9734/jpri/2022/v34i16A36428

Pan Facial Trauma Fracture Management: Case Report & Literature Review

Manjunath Vijapur, Nidhi Jenson Ukken, Vasanth Kattimani, Prasanna Kumar D., Aysha Kaleem Pasha & . Anuradha · Journal of Pharmaceutical Research International · 2022

Pan facial fractures involve the mandible, maxilla, and zygomatic complex at the same time, and are frequently associated with NOE and frontal bone fractures. Reconstruction of multiple facial fractures including the top and lower face should be handled as a jigsaw. To accomplish...

Open access Research Article 10.9734/jpri/2022/v34i16B35735

In-silico Screening and Identification of Novel Trypanothione Reductase Inhibitor from Leishmania

Misbahuddin M. Rafeeq, Ziaullah M. Sain, Khwaja Mohd Amir, Najat Binothman, Majidah Aljadani, Ahmad Alzamami, Norah A. Alturki, Abdulrahman Almutairi, Rashed Ahmed Alniwaider, Ahmed Hamdan Aloufi & Alaa Hamed Habib · Journal of Pharmaceutical Research International · 2022

The negative effects of leishmanicidal medications are numerous, and drug resistance to all of them has been observed. As a result, new medication development and the identification of novel therapeutic targets are critical. Leishmania major trypanothione reductase (Lm-TR), a NAD...

Open access Research Article 10.9734/jpri/2022/v34i16B35736

Insight on Hyperbaric Oxygen Therapy as an Adjunctive Treatmentin Diabetic Foot Ulcer: A Review

Hadaya M. Eladl, Nesma M. Allam, Walid Kamal Abdelbasset & Marwa M. Eid · Journal of Pharmaceutical Research International · 2022

Diabetic foot ulcers (DFU) are a source of major concern for both patients and health care systems. DFU is the most expensive and devastating complication of diabetes mellitus, which affect 15% of diabetic patients during their lifetime. That can lead to infection, gangrene, ampu...

Open access Research Article 10.9734/jpri/2022/v34i16B35743

A Simplified Review on Microsphere and Their Different Applications

Shital Bidkar, Sana Maniyar, Jayant Bidkar, Shubrajit Mantry & Ganesh Dama · Journal of Pharmaceutical Research International · 2022

Microspheres are small free-flowing particles with 1-1000um diameter and can be used to overcome the problems of conventional drug delivery. By altering the materials, methods, and polymers the therapeutic efficacy of microspheres containing drug content can be altered. We have d...

Open access Research Article 10.9734/jpri/2022/v34i16B35744