V. Muralidharan, Padmaja Vaddepalli, Shweta Saboo, Beebireddy Vidhya, Aenugu Jyothi, Nitin Gawai, Teja Kumar Reddy Konatham & M. Akiful Haque·Journal of Pharmaceutical Research International·2022
Background: Pharmacological treatments for diabetes are based on increasing insulin availability and improving insulin sensitivity. Today, glucagon-like peptide 1 (GLP-1) -based therapies aim to control glucose through DPP-4 inhibitors. DPP-4 is a transmembrane glycoprotein belon...
Open access
Research Article10.9734/jpri/2022/v34i15B35726
Background: Every surgery is associated with different levels of risks and complications. Cardiac surgeries would definitely cause moderate to severe anxiety because cardiac surgeries are riskier than other invasive procedures. Objective: To determine the effectiveness of binaura...
Open access
Research Article10.9734/jpri/2022/v34i15B35712
Aim: Chalcones are part of the selected group of chemical compounds related with diverse pharmacological activities such as antimicrobial, antiviral, antitumor, convulsion, anxiety, anti-inflammatory, andanalgesic. The aim of this study was to synthesize chalcones hydrazide deriva...
Open access
Research Article10.9734/jpri/2022/v34i15B35716
Postoperative pain management plays a vital role in the recovery after surgery. All these days opioids were used to accomplish this, but their use can be associated with adverse effects which can prolong the hospital stay. In the present era of opioid epidemic, it is our responsi...
Open access
Research Article10.9734/jpri/2022/v34i15B35717
Aim: The objective of preformulation study is to develop the elegant, stable, effective and safe dosage form by establishing kinetic profile, compatibility with other formulation excipients and physico-chemical parameters of new drug substance. This could provide important inform...
Open access
Research Article10.9734/jpri/2022/v34i15B35718
The aim of the study was to detect the prevalence of work-related Musculoskeletal Injuries among construction workers, to evaluate injury-related sick leave, and identify factors contributing to injury. the study was conducted and distributed to Saudi construction companies in th...
Open access
Research Article10.9734/jpri/2022/v34i15A35687
Background: Corona virus disease (COVID-19) has become a research priority since first reported case in Wuhan, China in December 2019. Pregnant women and fetuses represent a vulnerable group for which the disease may have effects not applicable to the general population. The aim...
Open access
Research Article10.9734/jpri/2022/v34i15A35690
Ammar A. Albokhari, Rajab Bresaly, Amani Hussain, Fatma A. Albarqi, Ahmad Almaghrabi, Sumayah I. Fallata, Abdulmalik H. Alsabban, Abdulrhman T. Alsawas, Ghassan K. Al Harazi & Deyaa Mukhtar·Journal of Pharmaceutical Research International·2022
Introduction: The most prevalent mental disorders which affect up to 33.7% of the population include generalized anxiety disorder, anxiety mixed with depression, panic attack, panic disorder, specific phobia, social phobia, and agoraphobia, all of which fall under the umbrella of...
Open access
Research Article10.9734/jpri/2022/v34i15A35689
Introduction: Osteoarthritis is a non-inflammatory degenerative disorder of joints causing disability in millions of people all over the world. WHO estimates that 10% of world’s population over 60 years of age suffers from osteoarthritis and 80% of people with osteoarthritis have...
Open access
Research Article10.9734/jpri/2022/v34i15A35691
Acne vulgaris is caused by Propionibacterium acnes, subsequently aggravated by Staphylococcus epidermidis, and Staphylococcus aureus. Pupalia lappacea (L.) Juss. It is a common weed found in Asia and tropical Africa. The current investigation is aimed to explore its antiacne prop...
Open access
Research Article10.9734/jpri/2022/v34i15A35694
Background: Statin drugs are using all over the world for the treatment of hypercholesterolemia. There is hypothesis that post menopausal women who used statin drugs long time can develop the onset of type 2 diabetes mellitus because statin drugs inhibit the signal transduction o...
Open access
Research Article10.9734/jpri/2022/v34i15A35695
Breast cancer is the most common cause of mortality in females globally and affects the lives of millions of women. It is a leading cause of mortality worldwide, but the dynamics have been changed because of advanced screening and treatment protocols [1]. In the United States, br...
Open access
Research Article10.9734/jpri/2022/v34i15B35696
Intestinal invaginations in adults are rare phenomenon . The most critical etiological causes are malignancies. The most common symptoms are abdominal pain, nausea, vomiting, inability to pass flatus and defecation, and distention in the abdomen due to intestinal obstruction. On...
Open access
Research Article10.9734/jpri/2022/v34i14B35679
Due to rapid industrialization and technological development, humans are constantly exposed to heavy metals at minimum to maximum tolerable levels. Arsenic is ubiquitously distributed and most concerned element now-a-days, inorganic arsenicals mainly enter into the body via the r...
Open access
Research Article10.9734/jpri/2022/v34i14B35662
Background and Aims: Chronic Hepatitis C virus is the leading cause of morbidity and mortality. Conversion to liver fibrosis and decompensated liver cirrhosis is common if left untreated. Direct-acting Antiviral agents (DAA) may help in liver fibrosis associated burden. Consideri...
Open access
Research Article10.9734/jpri/2022/v34i14B35680