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All published articles 7450

In-vitro Antioxidant, Antidiabetic Activities and Phytotoxic Profile of Alkanna tinctoria (Boraginaceae)

Rahmat Ali Khan, Aamir Khan Awan, Mushtaq Ahmed, Huda Alkreathy, Alia Gul, Amir Muhammad Khan, Arshad Mahmood, Asif Khan, Muhammad Nisar Ul Haq & Khalid Saleh Alzahrani · Journal of Pharmaceutical Research International · 2022

Plants are the most important source of biological compounds that are used to achieve biological activity. The originating of crude extracts of plants is broadly used as therapeutic drugs to treat various infectious damages. The present study was arranged to investigate the poten...

Open access Research Article 10.9734/jpri/2022/v34i14B35681

Cisplatin and Nano-particle Formulations of Cisplatin for Cancer Therapy: A Review

Popsy Raj, Bharat Lal, Manoj Gadewar, Anita Singh & G. K. Prashanth · Journal of Pharmaceutical Research International · 2022

Cisplatin (cis-(diammine)dichloridoplatinum(II)) is the first platinum-based compound approved by the United States Food and Drug Administration (FDA) (U.S.). This is a first-line chemotherapeutic treatment used alone or combined with other anticancer drugs to treat a broad spect...

Open access Research Article 10.9734/jpri/2022/v34i14A35636

Association of Non-alcoholic Fatty Liver Disease with Symptomatic and Asymptomatic Cholelithiasis: Cohort from Southeast Asian Patients

Abdul Hafeez Soomro, Jawaid Iqbal, Rehmatullah Bhatti, Falak Naz, Muhammad Arsalan & Muhammad Sadik Memon · Journal of Pharmaceutical Research International · 2022

Introduction: With increasing prevalence of metabolic syndrome, sedentary lifestyle, and diabetes mellitus the burden of non-alcoholic fatty liver disease (NAFLD) is also increasing along with its complications including gallstone disease. That is why, this study aims to determin...

Open access Research Article 10.9734/jpri/2022/v34i14A35647

Comparison between Modified Triangular Flap and Envelop Flap Techniques for Surgical Removal of Impacted Mandibular Third Molar

Bharti Kumari, Suneel Kumar Punjabi, . Lavina, Naeem Mustafa, Reham Iqbal & Salman Shams · Journal of Pharmaceutical Research International · 2022

Objective: To compare postoperative outcomes in surgical extraction of mandibular third molar with envelop flap versus modified triangular flap. Setting & Duration: Oral & Maxillofacial Surgery Unit at Faculty of Dentistry, Liaquat University of Medical and Health Science...

Open access Research Article 10.9734/jpri/2022/v34i14A35649

Neurofibroma of the Median Nerve Managed With Ultrasound Guided Nerve Block: A Case Report

Jeshnu Prakash Tople & Shilpa Shankar · Journal of Pharmaceutical Research International · 2022

Background: Median nerve neurofibroma can mimic carpal tunnel syndrome. In unilateral carpal tunnel syndrome, wrist imaging is suggested to exclude tumors. Diagnosis and management of peripheral nerve sheath tumors can be challenging. Case: This is a case report of 42-year-old fe...

Open access Research Article 10.9734/jpri/2022/v34i14B35652

The Effect of Conventional Lumbar Spine Surgery on the Lumbar Multifidus Fat Infiltration

Seyed Shahab Ghazi Mirsaeid, Ahmad Porashiedy Basharabadi, Ehsan Fallah & Mohammad Mansouri Nasab · Journal of Pharmaceutical Research International · 2022

Aims: Low back pain is considered as a common problem that affects most adults at least once in their lives. Almost 90% of people experience back pain during their lifetime. The total cost of treating chronic low back pain in the United States is estimated at more than $ 100 bill...

Open access Research Article 10.9734/jpri/2022/v34i14B35653

Genomics of Human Papillomavirus-induced Cervical Cancer

Shruti Umarvaish, Somendra Kumar & Anil Kumar · Journal of Pharmaceutical Research International · 2022

Human papillomavirus (HPV) induced cervical cancer is a serious health issue among most women from the least developed countries of the world due to scarcity of resources. HPVs have evolved a masterly infectious cycle that grabs the advantage of the self-renewal property of strat...

Open access Research Article 10.9734/jpri/2022/v34i14A35598

Evaluation of Morphology and Prevalence of Palatogingival Grooves on Affected Maxillary Anterior Teeth using Cone-Beam Computed Tomography

Ramhari Sathawane, Vidyarjan Sukhadeve, Romita Gaikwad, Dhiran Talatule, Pranada Deshmukh & Charwak Tayade · Journal of Pharmaceutical Research International · 2022

Background: Palatogingival groove (PG), a developmental anomaly, originates in cingulum and extends to varying distances apically. It is an ideal pathway for oral bacteria to invade periodontal tissues causing periodontal damage, pulp necrosis, apical periodontitis and endo-perio...

Open access Research Article 10.9734/jpri/2022/v34i14A35599

Guaifenesin Use in a Government Hospital in Al-Kharj

Nehad J. Ahmed, Dina I. Fouda & Ahmed I. Foudah · Journal of Pharmaceutical Research International · 2022

Aim: The present study aimed to describe the pattern of using guaifenesin in a government hospital in Al-Kharj. Methodology: This is a retrospective cross-sectional study that was conducted in a government hospital in Al-Kharj. Prescription data was collected from outpatient elec...

Open access Research Article 10.9734/jpri/2022/v34i13B35581

Length of Hospital Stay and Oseltamivir in Mild or Moderate Degree COVID-19 Patients in North Sumatra, Indonesia

Intan Lestari, Valentina Yurina & Diana Lyrawati · Journal of Pharmaceutical Research International · 2022

Background: Coronavirus disease 2019 is caused by a new strain of corona virus that affect the human respiratory tract. Aims: The aim of the study is to retrogressively review the use of antivirals on COVID-19 patients on their length of hospital stay (LoS) with mild and moderate...

Open access Research Article 10.9734/jpri/2022/v34i13B35582

Molecular Identification of Multi Drug-resistant Klebsiella pneumoniae Isolated from Neonates with Sepsis in Egypt

Farouk Hassan, Alaa Shawky, Ali A. Abdelrahman Ahmed, Abeer M. Hagras, Noha Alaa Eldin Fahim & Hayam S. Abdelkader · Journal of Pharmaceutical Research International · 2022

Neonatal sepsis is one of the most prevalent infections today, claiming the lives of almost one million newborns in developing countries. Our objective is to determine the bacteria that cause sepsis in newborns in Egyptian hospitals, as well as to discover their resistance profil...

Open access Research Article 10.9734/jpri/2022/v34i13B35583

Effect of Intracanal Cryotherapy on Surface Temperature Change in the Root Apex with Different Thickness; an Ex Vivo Study

Siddiqua Fatima, Asmat Jameel, Rizwan Jouhar, Muhammad Saqib, Jamshed Ahmed & Syed Akhtar Hussain Bokhari · Journal of Pharmaceutical Research International · 2022

Aims: To evaluate the effect of intracanal cryotherapy on surface temperature change in the root apex with different thickness. Study Design: Comparative Study. Place and Duration of Study: Operative Dentistry Department: Altamash Institute of Dental Medicine, Karachi, Pakistan:...

Open access Research Article 10.9734/jpri/2022/v34i14A35597

Analytical Methods for the Quantification of Ribavirin in Pharmaceutical Preparations, A Comparative Study

Serdar Gungor & İbrahim Bulduk · Journal of Pharmaceutical Research International · 2022

Ribavirin is a broad-spectrum antiviral drug and is used to treat diseases caused by many viral infections. In this study, high-pressure liquid chromatographic and UV-Vis spectrophotometric methods were developed, validated and statistically compared to determine the amount of ri...

Open access Research Article 10.9734/jpri/2022/v34i13A35569

A Systematic Medico Historical Review of Gokshura (Tribulus terrestris L.): A Traditional Indian Medicine

Ekta Manhas, Anil Kumar Singh & Sanjeev Kumar · Journal of Pharmaceutical Research International · 2022

Objective: This review aims to reveal the classic and experience-based traditional uses of Gokshura for health and wellness, and emphasizes the pharmacological and biochemical scientific evidence to confirm them. Data Source: The available literature on Gokshura from original Ayu...

Open access Research Article 10.9734/jpri/2022/v34i13A35570

Clinico-Hematological Study of Thrombocytopenia on the Basis of Bone Marrow Examination in a Tertiary Care Hospital

Vaidehi Nagar, Nanda Patil & Sujata Kanetkar · Journal of Pharmaceutical Research International · 2022

Background: Thrombocytopenia can occur in a variety of clinical conditions. Bone marrow aspiration is crucial for diagnosis. The purpose of this study was to investigate the causes of thrombocytopenia, its spectrum, and how to interpret the results of bone marrow aspiration. Aim...

Open access Research Article 10.9734/jpri/2022/v34i13A35571