Skip to content

All published articles 7450

Exploring the Relationship between Bowel Microbiota and Impaired Glucose Tolerance

Attia Ahmed Attia, Alaa Elmetwalli & Jayda G. Eldiasty · Journal of Pharmaceutical Research International · 2022

Background and Aim: Because of the large number of genes found in the gut microbiome, it has recently been determined that numerous human microorganisms have significant implications for human health. Aim: The significance of gut bacteria in the development of T2DM was investigat...

Open access Research Article 10.9734/jpri/2022/v34i5B36054

Cystitis Glandularis with Intestinal Metaplasia

Martha Rinnah Bijou, A. Josephine & S. Mary Lilly · Journal of Pharmaceutical Research International · 2022

Cystitis glandularis (CG) is an unusual proliferative disorder of the urinary bladder, which is characterized by transitional cells that have undergone glandular metaplasia.  Cystitis glandularis has occasionally been proposed as a precursor of adenocarcinoma by various studies....

Open access Research Article 10.9734/jpri/2022/v34i5A35407

A Novel Synthesis of 1,2,3triazole Substituted Pyrimidine, Pyrazole by Using 1,2,3triazolchalcone

A. J. Shadakshari, T. H. Suresha Kumara, H. B. V. & A. J. Yamuna · Journal of Pharmaceutical Research International · 2022

A series of 1- benzyl-5-methyl 1,2,3 triazole pyrimidine , 1- benzyl-5-methyl 1,2,3 triazole pyrazole were synthesised by using intermediate as phenyl Substituted prop-2-en-1-one .We obtained pyrazole when we treated propenones by using hydrazine hydrate and we obtained pyrimidin...

Open access Research Article 10.9734/jpri/2022/v34i5A36312

Hepatoprotective and Antioxidant Potential of the Sulphated Polysaccharides Fraction of Turbinaria ornata against paracetamol-induced Liver Damage in Rats

N. T. Ravindran & A. Mohamed Sadiq · Journal of Pharmaceutical Research International · 2022

Aims: To assess the potential of the sulphated polysaccharides fraction from brown marine alga Turbinaria ornata in protecting the liver damage induced by high dose of paracetamol. Study Design: In the present work, liver damage was induced in rats with paracetamol. Simultaneousl...

Open access Research Article 10.9734/jpri/2022/v34i5A35406

Effect of Angiotensin Receptor Blocker and Probiotics in Caffeine-Induced Anxiety Model

Pooja Verma, Siraj Anwar & Rohit Dutt · Journal of Pharmaceutical Research International · 2022

Aim:  To evaluate to anti-anxiety effectof probiotics and angiotensine receptor blocker in caffeine induced anxiety rat model. Methodology: The study was conducted in six groups (n=6). Caffeine was given intraperitoneally at a dosage of 25 mg/kg each day for 14 days. Blood sample...

Open access Research Article 10.9734/jpri/2022/v34i5A35408

Evaluation of Oral Health Related Knowledge and Practices among Support Staff at a Dental Institution: A Cross-sectional Survey

Amol Karagir, Tanushri Dalvi, Shrivardhan Kalghatgi, Shridevi Adaki, Aniruddha Shete, Anagha Shete & Shraddha Thorat · Journal of Pharmaceutical Research International · 2022

Aim: Knowledge of oral health is considered as one of the important factors as it influences the oral health related behaviour of an individual and oral hygiene practices in turn affects the oral heath related quality of life. Hence, the main aim of this survey was to assess the...

Open access Research Article 10.9734/jpri/2022/v34i5A35403

Screening of a Benzimidazole Derivative for Anthelmintic Activity with "Rule of 5" Approach

Chaitanya Prasad Meher, Vijaya Kumar Meher, Dharmendra Pradhan, Ashish Kumar Meher, Subodha Chandra Sahu & Soumitri Sahu · Journal of Pharmaceutical Research International · 2022

Purpose: Synthetic chemistry is an important route to develop new therapeutics for every disease. The presented research is focusing on the design, synthesis, evaluation, and Lipinski’s rule approach for a new biologically active benzimidazole derivative. Methods: The synthesis c...

Open access Research Article 10.9734/jpri/2022/v34i5A35404

Bioprocessing of Agricultural Waste (Banana Pseudostem) by Solid-State Fermentation (SSF) for Production of Cellulase

Sharanappa Achappa, Anil R. Shet, Veeranna S. Hombalimath, Laxmikant R. Patil & Shivalingasarj V. Desai · Journal of Pharmaceutical Research International · 2022

Cellulase was produced by Cellulomonas uda utilizing banana stem waste by solid state fermentation (SSF). The different parameters effects considered like particle size of substrate, pH(incubation and extraction), incubation period, temperature (incubation and extraction), media...

Open access Research Article 10.9734/jpri/2022/v34i5A35405

Assessment of Diabetic Retinopathy among the Diabetes Mellitus Type –II Patients at Tertiary Care Hospital of Hyderabad

Asadullah Jatoi, Noman Ahmed Shaikh & Mona Liza Mahesar · Journal of Pharmaceutical Research International · 2022

Background: Diabetes Mellitus is the major and leading cause of mortality among the local population of Asian countries. Routinely increase in the number of diabetes mellitus can produce financial and health crises. Aim and Objective: This study aims to evaluate the diabetic reti...

Open access Research Article 10.9734/jpri/2022/v34i4A35396

Awareness, Seeking Behaviors and Preventive Practices towards COVID-19 among Najran University Students

Abdullah I. Aedh, Nahid Kh. Elfaki & Mohammed Abdulrahman Alshahrani · Journal of Pharmaceutical Research International · 2022

Background: New corona virus (COVID-19), as an international health threat poses a challenge to physical as well as psychological resilience in the affected countries. Objective: The aim of this survey is to explore the level of awareness, health seeking behaviors and preventive...

Open access Research Article 10.9734/jpri/2022/v34i4A35418

Knowledge, Attitude and Practices (KAP) About Coronavirus SARS-CoV-2 among the General Public

G. Ramya Balaprabha, K. Priyanka, T. Ruth Jerusha, G. Hemanth, S. Catherine Sushmitha & T. Rama Rao · Journal of Pharmaceutical Research International · 2022

Background: A Knowledge, Attitude and Practices (KAP) survey is a quantitative method (predefined questions formatted in standardized questionnaires) that provides qualitative and quantitative information. Measure the extent of a known situation; provides new tangents of a situat...

Open access Research Article 10.9734/jpri/2022/v34i4A35419

Evaluating the Effectiveness of Various Vitamin D Formulations after Treatment

Bhushan Patil, Suyash Ambatkar, Kuldeep Chhatbar, Salahuddin Ahmed & Shrut Vasavada · Journal of Pharmaceutical Research International · 2022

Background: Vitamin D hasa vital starring role in bone metabolism which also promotes the absorption of calcium in the intestine. Thus, adequate level of vitamin D is of critical importance. Methods:A prospective, randomized, comparative, parallel-group study evaluated the effect...

Open access Research Article 10.9734/jpri/2022/v34i4B35397

Comparative Analysis of Short-Course Vs Long Course Antibiotic Therapy among Patients with Complicated Intra-Abdominal Infections

Amir Iqbal Memon, Samina Naz, Aisha Masroor Bhatti, Mashall Siddiqui, Riaz Ahmed Memon & Mansoor Ali · Journal of Pharmaceutical Research International · 2022

Background: Complicated intra-abdominal infections have become a major health challenge that merits safe and efficacious therapy. Antibiotic therapy is the treatment of choice, however the duration of antibiotic use is debatable. Objective: To compare the safety and efficacy of t...

Open access Research Article 10.9734/jpri/2022/v34i4B35398

Biochemical and Histological Evaluation of Penoxsulam Herbicide on an Animal Model

Vidushi Chaurasia, M. L. Aggarwal & Manoj Chandra Garg · Journal of Pharmaceutical Research International · 2022

Aims: Many herbicides react to the body system and might effect the activity of hormones in the human body. The present work aims to determine the potential impact of 90 days of repeated exposure to Penoxsulam herbicide by oral gavage on the Liver, Kidney, Thyroid endocrine profi...

Open access Research Article 10.9734/jpri/2022/v34i4B35399

Hemodialysis Catheter-Related Infections: Incidence in Temporary Catheters locked with Vancomycin and Heparin vs. Heparin-only

Ahmad Shamim Khan, Muhammad Kashif Khan, Mohammed Zubair, Shakeel khan, Usman Khalid & Khawar Sultan · Journal of Pharmaceutical Research International · 2022

Background: The increasing incidence of end stage renal disease (ESRD) patients initiating hemodialysis (HD) through a temporary HD catheter has caused the rise in catheter related infections and associated morbidity and mortality. An antibiotic lock solution (ALS) for the preven...

Open access Research Article 10.9734/jpri/2022/v34i4B35400