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All published articles 7450

A Comparison of Haematological Parameters of Obese Individual and Non-Obese at Omisanjana Area of Ado Ekiti, Ekiti State, Nigeria

Emmanuel I. Obeagu, Huba K. Rashid, Chukwum J. Okafor, Precious Omotunde & Zinai Gandu · Journal of Pharmaceutical Research International · 2022

Background: The global prevalence of obesity has been on the increase over the years constituting a major public health crisis. Aim: The study was done to evaluate the haematological parameters of obese and non obese individuals at Omisanjana area of Ado Ekiti, Ekiti State. Niger...

Open access Research Article 10.9734/jpri/2022/v34i4B35401

Effect of Concentrated and Dilute Hydrochloric Acid on Tooth Morphology: A Forensic Study

. Britina, V. Vishnu Priya, Abirami Arthanari, R. Gayathri, S. Kavitha & P. K. Reshma · Journal of Pharmaceutical Research International · 2022

Introduction: Teeth are the most durable structure present in our human body because of the presence of enamel which persist and resist destruction more than any other bony structure. Hard nature with high amount of resistance of tissues present in the tooth prevents any destruct...

Open access Research Article 10.9734/jpri/2022/v34i4B35402

A Review on Antiviral Activity of Favipiravir

Mariya Palathingal, M. Archana, K. Athulya Damodharan, . Nuaman, P. Ashisha & Akash Marathakam · Journal of Pharmaceutical Research International · 2022

The emerging severe acute respiratory syndrome coronavirus 2 pandemic endangers patients and physicians all over the world. The potency of COVID-19 antiviral drugs is still a matter of debate. The growing understanding of COVID-19 virology and clinical manifestations is resulting...

Open access Research Article 10.9734/jpri/2022/v34i3B35387

Simultaneous Estimation of Bilastine and Montelukast in Bulk by Rp-hplc and Assessment of Its Applicability in Marketed Tablet Dosage Form

Swati M. Andhale & Anna Pratima G. Nikalje · Journal of Pharmaceutical Research International · 2022

Aim: This study proposes to develop and validate the RP-HPLC method for Bilastine and Montelukast and to substantiate the RP-HPLC analysis bestowing to ICH validation guideline Q2R1. Place and Duration of Study: Y. B. Chavan College of Pharmacy, Aurangabad, MS, India, between Jan...

Open access Research Article 10.9734/jpri/2022/v34i3B35388

Phytochemical, UV-Visible and FTIR Assessment along with in vitro Antioxidant Activity of Methanolic Extract of Tephrosia purpurea Linn Root

Pranita S. Jirvankar, D. Khobragade, S. Chandewar, A. Pimpale, R. Gawali, A. Lokade, A. Maske & R. Agrawal · Journal of Pharmaceutical Research International · 2022

Aims: The original phytochemical, UV-Visible, and FTIR Spectral estimation of Tephrosia purpuria root was the subject of this study. Natural phytoconstituents were all found in methanolic extracts from the root of Tephrosia purpuria. Study Design:  Experimental research work. Met...

Open access Research Article 10.9734/jpri/2022/v34i3B35389

Acute Kidney Injury after Ureteral Obstruction Due to Signet Ring Cell Adenocarcinoma of the Bladder

Waqas Ahmad Khalid, Naqash Siddique Gorsi & Iram Shehzadi · Journal of Pharmaceutical Research International · 2022

Background and Objectives: Acute Kidney Injury (AKI) due to bilateral ureteral obstruction in older patients typically raises concerns of abdominal, retroperitoneal, or pelvic neoplasms. Aim of the present paper is to analyse the acute kidney injury after ureteral obstruction due...

Open access Research Article 10.9734/jpri/2022/v34i3B35391

Comparative Evaluation of Alpha-Amylase and Alpha- Glucosidase Inhibitory Potential of Aqueous Seed Extract of Trigonella Foenum-Graecum and Moringa Oleifera - An In vitro Study

N. Prithiksha, R. Gayathri, V. Vishnu Priya, J. Selvaraj & S. Kavitha · Journal of Pharmaceutical Research International · 2022

Background: Trigonella foenum-graecum is one of the commonly used herbs in food. Moringa oleifera is a source of food, accommodation and conventional medicine for many peoples in the developing countriesThe seeds of both the plants were explored for antidiabetic potential. Method...

Open access Research Article 10.9734/jpri/2022/v34i3B35392

Potential Application of Wharton's Jelly-derived Mesenchymal Stem Cells Conditioned Medium (WJMSCs-CM) on Delayed Wound Healing: A Case Report

Cindy Christella Chandra, Yurike Indah Pratiwi & Sukmawati Tansil Tan · Journal of Pharmaceutical Research International · 2022

Delayed wound healing refers to wounds that do not repair the wounded tissue's integrity in a timely manner, prolonging the inflammatory, proliferative, and remodelling phases of healing. Delayed wound healing increases the chance of infection, causing discomfort, lowering the qu...

Open access Research Article 10.9734/jpri/2022/v34i4A35393

The Application of Hydroxyapatite in Socket Preservation: A Review of the Past and Current Advancement

Nurul Saadah Razali, Luay Thanoon Younis & Mohamed Ibrahim Abu Hassan · Journal of Pharmaceutical Research International · 2022

Alveolar ridge dimensional loss is a physiologic consequence of tooth extraction. Often, this event causes compromised feasibility of implant placement, prosthetic rehabilitation and esthetic outcome. As an attempt to minimize the shrinkage of the alveolar bone, socket preservati...

Open access Research Article 10.9734/jpri/2022/v34i4A35394

Statins for the Treatment of Liver Fibrosis in Chronic Hepatitis-C Patients

Amina Abbassi, Ashok Kumar Lohano, Anwar Ali Jamali, Farah Mughul, Muhammad Khalid Shaikh, Muhammad Zain Shaikh & Arslan Ahmer · Journal of Pharmaceutical Research International · 2022

Background: Hepatitis C virus (HCV) is one of the most common causes of chronic liver disease and the leading indication for liver transplantation worldwide. Chronic hepatitis C (CHC) leads to cirrhosis and hepatocellular carcinoma (HCC). Statins have gained attention for their p...

Open access Research Article 10.9734/jpri/2022/v34i4A35395

Effectiveness of Knotless Barbed Sutures for Intraoral Closure after Impacted Mandibular Third Molar Surgery: A Split Mouth Randomized Clinical Trial

Sneha Krishnan, Senthilnathan Periasamy & M. P. Santhosh Kumar · Journal of Pharmaceutical Research International · 2022

Objectives: The purpose of this clinical trial is to assess the efficiency of 3-0 knotless barbed suture (polydioxanone) with 4-0 polyglactin 910 (vicryl) in wound closure following impacted mandibular third molar surgery. Methods: The split-mouth study involved 20 patients who w...

Open access Research Article 10.9734/jpri/2022/v34i3A35385

Extracellular Proteases Production in Methicillin Resistant Staphylococcus aureus Clinical Isolates

Abdul Nabi Jatt, Ameet Kumar, Shaista Bano, Sarfraz Ali Tunio, Nazakat Hussain Memon, Farhatullah Kandhro, Abdul Sami Dahri & Babar Aijaz Memon · Journal of Pharmaceutical Research International · 2022

Methicillin resistant Staphylococcus aureus (MRSA) bacteria are responsible for wide range of infections, while the treatment of such infections has become a challenge for public health. Moreover, the production of extracellular proteases by these pathogens has recently been cons...

Open access Research Article 10.9734/jpri/2022/v34i3A35382

A Study to Determine an Association between ABO Blood Groups and Coronavirus Disease 2019

Sarita Mulkalwar, Zenia Aadil Elavia, Biswajit Chaklader, Tushar Patil, Abhi Patel, Sudhir Laxman Jadhav & A. V. Tilak · Journal of Pharmaceutical Research International · 2022

Introduction: The Coronavirus pandemic has led millions to succumb to the disease across the world, and overwhelmed the health care system. In this study we aimed at identifying whether the risk of Covid-19 infection is associated with ABO blood groups. Methods: We obtained data...

Open access Research Article 10.9734/jpri/2022/v34i3A35383

Evaluation of Activated Partial Thromboplastin Time and Prothrombin Time in HIV and TB Patients in Owerri Metropolis

Ijeoma Leticia Okoroiwu, Emmanuel Ifeanyi Obeagu, Queen Braxton N. Anaebo & Olivia Walter · Journal of Pharmaceutical Research International · 2022

Background: Human immunodeficiency Virus (HIV) and Tuberculosis (TB) are the leading infectious diseases with high morbidity and mortality in the developing countries; it has been known to be associated with some coagulation abnormalities especially as the disease progresses. Aim...

Open access Research Article 10.9734/jpri/2022/v34i3A35560