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All published articles 773

Therapeutic Insights into Mangifera indica: Managing Diabetes and Hyperlipidemia in Alloxan-treated Rats

Somaya Jannat Shawon, Sabbir Khan, Sara Rahmat, Mafruza Khanam Prottasha, Md Navid Rahman Nafsan, Sadia Tasnim & Israt Jahan Rasna · Journal of Complementary and Alternative Medical Research · 2025

People have used herbal medicine for healing since the dawn of human civilization. This study investigated the antidiabetic efficacy and lipid profile of Mangifera indica. We evaluated the antidiabetic activity through the alloxan-induced diabetic model. The 750 mg/kg dosage in g...

Open access Research Article 10.9734/jocamr/2025/v26i1617

Investigating the Anti-diabetic and Lipid-regulating Properties of Eclipta alba in Alloxan-induced Diabetes

FM. Sharifuzzaman Shohan, Susmoy Dey, Tasin Islam Pranto, Md. Rahmat Ullah, Sadia Tasnim, Juliana Aditi Baroi & Israt Jahan Rasna · Journal of Complementary and Alternative Medical Research · 2025

Since the dawn of human civilization, humanity has used herbal medicine for medicinal purposes. Traditional medicine has experienced a substantial surge in popularity in recent years. This research sought to evaluate the antidiabetic effectiveness and lipid profile of Eclipta alb...

Open access Research Article 10.9734/jocamr/2025/v26i1618

Complementary and Alternative Medicine Use among Dermatology Outpatients in Southeastern Nigeria: A Tertiary Hospital Study

Anaje Chetanna Chioma, Okpala Chibuzor Ifeanyi, Enechukwu Nkechi Anne, Ezejiofor Ogochukwu Ifeanyichukwu, Malachy Divinefavour Echezona & Nkesi John Chukwuebuka · Journal of Complementary and Alternative Medical Research · 2025

Background: Complementary and Alternative Medicine (CAM) is widely used globally, including among dermatology patients. CAM includes different practices not typically part of conventional medicine and is classified into five categories, including biologically based therapies and...

Open access Research Article 10.9734/jocamr/2025/v26i1619

Nanotechnology in COVID-19 and SARS-CoV-2: Advances in Antiviral Therapies and Applications

Erfan Dehesh & Fahad Dehesh · Journal of Complementary and Alternative Medical Research · 2025

Innovative diagnostics, therapeutics, and preventive strategies must be developed to combat the emergence of new viral pathogens and the resurgence of known viruses. Using nanotechnology to enhance antiviral therapeutic efficacy through improved drug delivery, targeted viral inhi...

Open access Research Article 10.9734/jocamr/2025/v26i1616

Exploring the Therapeutic Efficacy of Ethanolic Extract of Benincasa hispida in Alloxan Induced Diabetic Rats

Ikram Wahid Toha, Shafia Islam Promi, Sampa Barai, Abdullah Al Mamun, Shabira Sagir, Sadia Tasnim, Ambia Khatun Sony & Israt Jahan Rasna · Journal of Complementary and Alternative Medical Research · 2025

Since the dawn of civilization, humans have used herbal medicine to treat medical ailments. This study seeks to evaluate the efficacy of Benincasa hispida as an anti-diabetic agent and its impact on lipid profiles. We assessed the efficacy of the anti-diabetes medication using th...

Open access Research Article 10.9734/jocamr/2025/v26i1615

Effect of Ninety-day Repeated Adiministration of Leaf Extract of Solanum anomalum on Rats

Jude E. Okokon, Idongesit C. Etuk, John A Udobang, Chinyelu C. Osigwe, Uwaeme Ugonma Florence & Uduak P. Ise · Journal of Complementary and Alternative Medical Research · 2025

The leaves and fruits of Solanum anomalum Thonn. ex Schumach are used locally for the treatment of pains, fever and malaria among others. Effect of 90-day repeated administration of S. anomalum leaf extract on rats was investigated. Oral administration of the leaf extract (70, 14...

Open access Research Article 10.9734/jocamr/2025/v26i1614

Attenuating Ketamine-Induced Nephrotoxicity with Bryophyllum pinnatum Extract: Biochemical and Histological Investigation

Precious Ojo Uahomo & Joshua Charles Isirima · Journal of Complementary and Alternative Medical Research · 2025

Background: Ketamine, a widely used anesthetic agent, has been shown to induce nephrotoxicity, characterized by increased kidney function markers and structural damage. Despite its therapeutic applications, the adverse effects of ketamine on the kidneys necessitate the exploratio...

Open access Research Article 10.9734/jocamr/2025/v26i1612

Systematic Review and Meta-Analysis of Hibiscus sabdariffa in Hypertension Management

Raphael Nyarkotey Obu · Journal of Complementary and Alternative Medical Research · 2025

This study systematically reviews and meta-analyzes existing evidence on the efficacy of Hibiscus sabdariffa in managing high blood pressure. A comprehensive search of databases, including PubMed, Scopus, and Web of Science, identified randomized controlled trials and observation...

Open access Research Article 10.9734/jocamr/2025/v26i1613

Protective Effects of Flavonoids-rich and Saponins-rich Extracts from Tiger Nuts and Date Fruits on Prostate Histoarchitechture in Aluminum-exposed Wistar Rats

Agaba, Eric Agim, Ujah, Williams Oche, Enang, Kingsley Bassey, Fischer, Victor A, Emmanuel I. Odom & Adie, Christopher Utsu · Journal of Complementary and Alternative Medical Research · 2025

Aim: To evaluate the histological effects of flavonoid and saponin fractions from Cyperus esculentus (tiger nuts) and Phoenix dactylifera (date fruits) on the prostate gland of Wistar rats exposed to aluminum chloride, focusing on their potential protective properties against alu...

Open access Research Article 10.9734/jocamr/2025/v26i1610

Histopathological Study of Subacute Administration of Saccharum officinarum Leaf Extract on Some Organs of Rat

Jude E. Okokon, John A. Udobang, Chinyelu C. Osigwe, Uwaeme Ugonma Florence, Uduak P. Ise & Utibe A. Edem · Journal of Complementary and Alternative Medical Research · 2025

The leaves of Saccharum officinarum (Family-Poaceae) is employed traditionally for ethnotherapy of malaria and fever among others. Evaluation of subacute administration of Saccharum officinarum leaf extract for possible effect on organs of rats was carried out. The leaf extract (...

Open access Research Article 10.9734/jocamr/2025/v26i1611

Community Perceptions of Traditional and Pharmaceutical Hypertension Treatments in Vryman’s Erven, Berbice, Guyana

Obena Vanlewin, Andrew Hutson, Karishma Jeeboo, Bibi Ally-Charles, Charlan Abrams & Cecil Boston · Journal of Complementary and Alternative Medical Research · 2024

This study explores the integration of traditional and pharmaceutical remedies in managing hypertension in the rural Berbice community (Vryman’s Erven), New Amsterdam, Guyana. Expanding the use of these remedies means evaluating their effectiveness, relevance to the culture, and...

Open access Research Article 10.9734/jocamr/2024/v25i12609

Biogenic Synthesis and Comparative Assessment of the Antimicrobial Activities of Silver and Zinc Nanoparticles of Dialium guineense Leaf Extract against Human Pathogens

Goodnews Onyedikachi Ikeh, Ugwu PE, Rita Chiamaka Okpoto, Njoku EA, Charles C. Diovu & Adonu CC · Journal of Complementary and Alternative Medical Research · 2024

Aim: The study aimed to perform a comparative evaluation of the antimicrobial activities of green synthesis of silver and zinc nanoparticles. Study Design: Experimental. Methodology: A biogenic and facile method of synthesis of silver and zinc oxide nanoparticles (DGL—SNPs and DG...

Open access Research Article 10.9734/jocamr/2024/v25i12607

Hepatoprotective Effects of Talinum Triangulare Aqueous Extract on Paracetamol-Induced Liver Damage in Wistar Rats: A Histomorphological Study

Achi Franklyn U., Chiagozie King-Bertram C., Esther I. Etu, Chinedu Maduka P., Ekoh Adaorah J. & Nyejirime, Young W. · Journal of Complementary and Alternative Medical Research · 2024

Background and Aim: Many vital bodily processes are carried out by the liver, and if it develops a disease, those processes may cease, which might seriously affect the function of the body. Talinum triangulare has been documented to possess hepato-protective, antioxidant and anti...

Open access Research Article 10.9734/jocamr/2024/v25i12608

Evaluating the Antibacterial Potential of Commercial Herbal Mixtures against Clinical Isolate of Salmonella typhi: An In-vitro Experimental Analysis

Isaac Baffour Awuah, Dennis Bardoe, Nelson Danyomah Wepia, Denis Dekugmen Yar, Daniel Hayford, Robert Bagngmen Bio, Simms Ofosu, Collins Saanle Eng, Osei-Sarfo Kantanka, George Ahiaka, Francisca Serwaa Oppong, James Azupero & Paul Acheampong · Journal of Complementary and Alternative Medical Research · 2024

Background: Typhoid fever incidence has continuously increased, particularly in developing countries. As a result, there has been an influx of preference for herbal remedies to meet the growing demand. However, the increasing demand for these herbal preparations has created room...

Open access Research Article 10.9734/jocamr/2024/v25i12605

Selected Factors that Influence Nonadherence to Antituberculosis Drug Regimen among Tuberculosis Patients at Two (2) Rural Clinics in Guyana, South America

Bhuwandai Gharbaran, Falana Daly, Viannie Ferreira, Jewel Edmondson-Carter, Cecil Boston & Andrew Hutson · Journal of Complementary and Alternative Medical Research · 2024

Objectives: This study aimed to identify and compare the factors influencing non-adherence to antituberculosis drug regimens at two rural clinics in Guyana. Methods: A quantitative, cross-sectional design was employed to examine adherence barriers among tuberculosis (TB) patients...

Open access Research Article 10.9734/jocamr/2024/v25i12606