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All published articles 773

The Role of Plants Having Antimicrobial Properties in the Management of Mental Health Disorders: A Review

Adeniyi, Grace P., Igbokwe, Christopher O., Mahady Gail B. & Adeniyi, Bolanle A. · Journal of Complementary and Alternative Medical Research · 2024

Millions worldwide suffer from mental health disorders such as depression, anxiety, and schizophrenia, underscoring the need for effective, accessible treatments. While conventional therapies have made strides in managing these conditions, challenges such as side effects and high...

Open access Research Article 10.9734/jocamr/2024/v25i11588

Subacute Toxicity Study of Alchornea cordifolia Ethanolic Leaf Extract on the Pituitary Gland of Wistar Rats

Eric Agim. Agaba, Williams Oche. Ujah, Sadeyeng Ernest Anani & Victor A. Fischer · Journal of Complementary and Alternative Medical Research · 2024

Introduction: Herbal medicines are plant-based products used to treat various illnesses and their uses have dramatically increased over the past years in many developed and developing nations. Alchornea cordifolia is one of these plants with reports of its use in health promotion...

Open access Research Article 10.9734/jocamr/2024/v25i11587

Gas Chromatography-Mass Spectrometry and Fourier Transform Infrared Spectroscopy Analysis of Potential α-Glucosidase Inhibitors from Terminalia catappa Leaf Extracts

Abdul-Matiin Issahaku & Lateef Adebayo Oseni · Journal of Complementary and Alternative Medical Research · 2024

Aims: Postprandial hyperglyceamia is often caused by insulin insufficiency or cellular glucose uptake complications, and conventional treatments often yield undesirable side effects. The aim of the current work was to assess the α-glucosidase inhibitory activities of T. catappa l...

Open access Research Article 10.9734/jocamr/2024/v25i11586

Evaluation of Antioxidant and Breast Cancer Cytotoxicity of Beta vulgaris and Daucus carota Methanol Extracts

Ramesh Kumar, Vandana Singh, Laxmi Devi, Sidhanshu Kumar, Sanjay Kumar, Rekha Lagarkha & Maneesha Pandey · Journal of Complementary and Alternative Medical Research · 2024

Breast cancer is the world's most frequent malignancy among women. Many dietary antioxidants have been shown to help prevent oxidative stress, which has been linked to a variety of diseases, including cancer. Many chronic diseases, such as cancer, can be avoided by eating fruits...

Open access Research Article 10.9734/jocamr/2024/v25i11585

Analgesic Effects of Methanol Leaf Extracts from Datura alba ness in Male Wistar Rats through Reduction of C-reactive Protein Levels

Blessing Zeinab Ovili-Odili, Olaghaguo Macstephen Adienbo, Tarela Melish Elias Daubry & Bruno Chukwuemeka Chinko · Journal of Complementary and Alternative Medical Research · 2024

Introduction: The increasing interest in utilizing natural products from medicinal plants for pain management stems from their wide availability and minimal side effects. This study aims to evaluate the toxicity profile of Datura alba ness (DAN) extracts and assess their potentia...

Open access Research Article 10.9734/jocamr/2024/v25i11583

Determination of Astrocyte Reaction Using Glial Fibrillary Acidic Protein (GFAP) Following Aluminium Chloride Induced Hippocampus Damage of Adult Wistar Male Rats Treated with Ethanolic Extracts of Carpolobia lutea at Different Doses

Lawson Clement, Jacks Tamunotubo W., Ordu Kenneth S. & Orupabo Clinton D. · Journal of Complementary and Alternative Medical Research · 2024

Background: Aluminium is a well-established neurotoxicant involved in the etiology of neurodegenerative diseases. Carpolobia lutea, commonly called cattle stick or poor man’s candle belongs to the plant family polygalaceae. It is a small tree native to West and Central tropical A...

Open access Research Article 10.9734/jocamr/2024/v25i11584

Neuroprotective Effects of Heinsia crinita and Coconut Water in a Scopolamine-Induced Alzheimer's Model in Albino Rats: Biochemical Changes, Cellular Health, and Neuronal Activity

Theresa E. Isamoh, Sadeyeng Anani, Nsikak Umoh, Michael Oku, Eru Eru Mba, Eric Agaba, Williams Nnenna & Emmanuel I. Odom · Journal of Complementary and Alternative Medical Research · 2024

Aim: This study aimed to investigate the potential therapeutic effects of Heinsia Crinita and Tender Coconut water (TCW) on Alzheimer's disease, focusing on their phytochemical composition, antioxidant activity, and anti-inflammatory effects. The study aimed to identify potential...

Open access Research Article 10.9734/jocamr/2024/v25i11582

Nutritional Genomics: The Use of Personalized Diets for Managing Depression

Ewaoluwa Promise Owoyemi, Kernen Paul Agwaza, Ogbonna Kosisochukwu Doris, Donatus Chigozie Egwuatu, Rachael Olakunmi Ogunye, Peter Chidendu Anene, Eberechukwu Osinachi Azubuike, Jane-Frances Chinenye Ojobor, David Odanibeh, Oluwabusola Oluwakorede Asenuga & Chibuzo Valentine Nwokafor · Journal of Complementary and Alternative Medical Research · 2024

Millions worldwide suffer from major depression, and recent studies have highlighted the effect of diet on mental health. However, research using nutritional genomics to create personalized diets for managing depression is still limited. This review explores the role of nutrition...

Open access Research Article 10.9734/jocamr/2024/v25i11581

A Retrospective Comparative Analysis of Chest Radiograph Findings Among Patients in a Tertiary Hospital in Rivers State, Nigeria

Vivian Ndidi Akagbue & Enighe W Ugboma · Journal of Complementary and Alternative Medical Research · 2024

Background: Chest radiograph is an imaging modality that uses ionizing radiation used for the evaluation of the thorax and its content. It is readily available, accessible, cheap and greatly employed in the health sector for various reasons.  Objective: Chest radiographs serve as...

Open access Research Article 10.9734/jocamr/2024/v25i11580

Ameliorative Effect of Curcuma longa Ethanolic Extract on the Histology, Hepatic Glycogen Content and Some Biochemical Parameters of the Liver in Streptozotocin-Induced Hyperglycemic Wistar Rats

Mfon I. Akpaso, Lydia E. Bassey, Sadeyeng E. Anani, Michael E. Oku, Williams A. Nnenna, Nsikak M. Umoh, Eru M. Eru, Elton N. Takim, Gideon Uzor, Theresa E. Isamoh & Eric A. Agaba · Journal of Complementary and Alternative Medical Research · 2024

Introduction: Diabetes mellitus is a life threatening disease that requires immediate medical treatment. Numerous medicinal plants have been known for their anti-diabetic effects and Curcuma longa (turmeric) is one of them. This attribute is possible due to the pharmacological pr...

Open access Research Article 10.9734/jocamr/2024/v25i11579

Anti-Lipidemic and Anti-Glycemic Potential of Lactational Exposure to Flavonoid from Hibiscus sabdariffa in Offspring of Wistar Rats

Nyejirime Young Wike, Ndubuisi Nonso Richards, Esther Ifeyinwa Etu, Uzoefuna Casmir Chima, Patrick Alor, Judith Uzezi Egbo, Akhigbe Agatha Oge, Obianuo Chineta Sussan & Agbor Joseph Ikenna · Journal of Complementary and Alternative Medical Research · 2024

Background and Aim: An individual's growth, organ development, physical makeup, and health are significantly influenced by their nutrition in the early stages of development. Hibiscus sabdariffa have been associated with beneficial effects  on human health. The anti-lipidemic and...

Open access Research Article 10.9734/jocamr/2024/v25i10577

Mitigating Cadmium-Induced Reproductive Toxicity in Male Wistar Rats: Protective Role of STC30, a Polyherbal Formulation

Nwangwa J.N, Aribo E.O & Okpo-Ene A.I · Journal of Complementary and Alternative Medical Research · 2024

Background: Cadmium, one of the most toxic heavy metals but which finds its presence in many applications and the environment impairs male reproductive function via oxidative stress. There is a growing interest in the development and usage of polyherbal remedies with high antioxi...

Open access Research Article 10.9734/jocamr/2024/v25i10578

An Assessment of Hepatoprotective Activity of Glycyrrhiza glabra Root Extract against Hepatic Injured Rodent Model

Sampa Barai, Tahsina Tabassum, Abdullah Al Mamun, Shabira Sagir & Ikram Wahid Toha · Journal of Complementary and Alternative Medical Research · 2024

Hepatotoxicity, or liver damage, is caused by hepatotoxins, which can originate from chemicals, dietary supplements, prescription drugs, and medicinal plants. Nowadays, medicinal and aromatic plants are excellent resources for creating novel drugs and curing both psychological an...

Open access Research Article 10.9734/jocamr/2024/v25i10575

Hepatoprotective Activity of Bixa orellana Plant Extract against Hepatotoxicity in Rodent

Sadiya Binte Rashid, Sadia Adnin Oyshi, Bushratul Jannat, Md Shakil, Angelina Samantha Halder & Zulqarnain Haider · Journal of Complementary and Alternative Medical Research · 2024

Introduction: Hepatotoxicity, or liver damage, can result from exposure to toxic substances such as medications, chemicals, alcohol, and environmental pollutants, affecting approximately 1.5 billion people worldwide. Although synthetic drugs offer therapeutic benefits, they often...

Open access Research Article 10.9734/jocamr/2024/v25i10576

An Assessment of Hepato-protective Activity of Hygrophila auriculata Root Extract against Hepatic Injured Rodent Model

Md. Rahmat Ullah, Ankita Bose, Tasin Islam Pranto, FM. Sharifuzzaman Shohan, Faisal Ahmed Shakil & Juliana Aditi Baroi · Journal of Complementary and Alternative Medical Research · 2024

Liver is a crucial organ that is susceptible to several hepatotoxins causing hepato-toxicities. These days, medicinal plants have been considered to be more promising compared with the conventionally utilized medications for hepatic treatments. In light of the dire circumstances...

Open access Research Article 10.9734/jocamr/2024/v25i10574