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All published articles 773

Evaluation of the Effect of Date Palm [Phoenix dactylifera] Fruit Extract on Methotrexate-Induced Reproductive Toxicity in Male Rats

N. C. Azubuike & C. C. Opoh · Journal of Complementary and Alternative Medical Research · 2022

Background: Phoenix dactylifera L. in the Palmae family (Arecaceae) is commonly known as Date palm. Its fruit is popularly consumed as food and also used as a herbal remedy for fertility enhancing effects in males. Aim: The present study was designed to explore the effect of P. d...

Open access Research Article 10.9734/jocamr/2022/v17i430339

Genotoxicity-Suppressing Effect of Sophora japonica L. Aqueous Extract

Yuki Tahara, Satomi Hayashi-Shita, Takanori Nakamura, Ryo Murashige, Kayoko Yamasaki, Katsutoshi Matsumoto, Akira Hasegawa, Takayuki Saito, Kumiko Sato, Tetsuo Honma, Ayumi Yamamoto, Hirotada Arai, Yoshihiro Kadoma, Satomi Kawaguchi, Yasuaki Kikuchi, Kazuyuki Furuya & Yu F. Sasaki · Journal of Complementary and Alternative Medical Research · 2022

The dry flower buds of Sophora japonica L. are used as a hemostatic agent in traditional Chinese medicine. In the comet assay, aqueous extracts of S. japonica decreased and increased the tail length significantly in cultured human lymphoblastoid WTK1 cells exposed to UV in the ab...

Open access Research Article 10.9734/jocamr/2022/v17i430338

Therapeutic Benefits of Naturopathy Douches in Hydrotherapy

N. Vijayaraghavan & V. R. Dhilip · Journal of Complementary and Alternative Medical Research · 2022

Naturopathy is an “alternative medicine” which doesn’t belong to any medicine. Nature itself comprises five major elements which are space, air, fire, water, and earth. Hydrotherapy or water therapy is one of the universal solvents having an immense impact on the human body and m...

Open access Research Article 10.9734/jocamr/2022/v17i430337

Microcurrent Frequencies’ Effect on the Cell Membrane Potential

Marcus Schmieke & Mikkel Aagaard · Journal of Complementary and Alternative Medical Research · 2022

Research shows that cellular and mitochondrial (ΔΨm) membrane potentials are strong indicators of cellular physiology. In this paper we review further research suggesting that microcurrent frequencies can positively influence both these membrane potentials. The goal of this resea...

Open access Research Article 10.9734/jocamr/2022/v17i430336

Synergistic Effect of Some Essential Oil Extracted from Three Nigeria Spices against Some Pathogenic Organisms

T. M. Ilesanmi, A. C. Olaleye & O. O. Oladipo · Journal of Complementary and Alternative Medical Research · 2022

Introduction: Essential oils of plants and their other products from secondary metabolism have had a great usage in folk medicine, food flavoring, fragrance, and pharmaceutical industries. Aims: This study sought to evaluate the phytochemical properties of the oil extracted from...

Open access Research Article 10.9734/jocamr/2022/v17i330335

Therapeutic Evaluation of Selected Herbal Supplements on Thyroid Hormones of Cyanide – Induced Hyperthyroidism in Female Albino Rats

B. N. C. Onuoha, I. Elekima, D. G. Tamuno-Emine & E. O. Nwachuku · Journal of Complementary and Alternative Medical Research · 2022

Aim: To evaluate the therapeutic effect of some herbal supplements on thyroid hormones of cyanide – induced hyperthyroidism in Female Albino Rats. Study Design:  Experimental study. Place and Duration of Study: Department of Animal and Environmental Biology,                      ...

Open access Research Article 10.9734/jocamr/2022/v17i330334

Insightful Valorization of Biological Activities of Flax Seed (Linum usitatissimum) through Experimental and Computer Aided Mechanisms

M. Ganga Raju, Charitha Burri & N. V. L. Suvarchala Reddy V · Journal of Complementary and Alternative Medical Research · 2022

Flax also known as common flax or linseed, is a flowering plant, Linum usitatissimum, in the family Linaceae. The current study used haloperidol-induced catalepsy and reserpine antagonism to investigate in vivo anti- Parkinson's activity and in silico approaches like docking stud...

Open access Research Article 10.9734/jocamr/2022/v17i330333

The Mixture Aqueous Extracts from Oxalis corniculata L. and Acmella caulirhiza Delile Accelerates Bone Healing in Fractured Rats

Florence Tsofack Ngueguim, Josiane Jouonzo, Jean Hubert Donfack, Raceline Kamkumo Gounoue, Jean Philippe Djientcheu, Clarice Noussi Djouwoug, Rodrigue Ngapout Fifen, Paul Désiré Djomeni Dzeufiet & Théophile Dimo · Journal of Complementary and Alternative Medical Research · 2022

Background: Bone fracture is a condition in which there is a break in the continuity of the bone due to traumatic or pathological factors. Fracture management includes orthopedic, surgical, non-surgical techniques and drug treatments. However, these treatments possess a limitatio...

Open access Research Article 10.9734/jocamr/2022/v17i330332

Establishment of Optimal Conditions to Extract Bioactive Substances from Gamazumi Using Supercritical Carbon Dioxide

Kumiko Sato, Takayuki Saito, Akira Hasegawa, Yoshihiro Kadoma, Marina Kobune, Yoshio Sato, Satomi Kawaguchi, Ayumi Yamamoto, Kazuyuki Furuya, Takanori Nakamura & Yu F. Sasaki · Journal of Complementary and Alternative Medical Research · 2022

The fruits of Gamazumi (Viburnum dilatatum THUNB) have been previously reported to suppress the adverse effects of oxidative stress in rats.  To reduce time and cost, we attempted to establish optimal conditions for extracting bioactive components from Gamazumi fruits using super...

Open access Research Article 10.9734/jocamr/2022/v17i230327

Formulation Optimization of an Improved Traditional Medicine from the Stem Bark Extract of Mangifera indica L. using Design of Experiments (DOE) Strategy

Tembe Estella Fokunang, Ekwoge Hilda Tonge, Bayaga Herve, Tchadji Vanessa, Njinkio Nono Borgia, Nene Ahidjo, Mogue Ingrid, Tabi Yves Omgba, Zintchem Roger, Nnanga Nga Emmanuel, Ngameni Bathelemy & Fokunang Charles Ntungwen · Journal of Complementary and Alternative Medical Research · 2022

Introduction: Improved Traditional Medicines (ITMs), a recent concept by the World Health Organization (WHO) was introduced to promote the rational use of herbal medicine for primary health care in developing countries. The ITM by WHO andAIPO have categorized into 4 categories wi...

Open access Research Article 10.9734/jocamr/2022/v17i330331

Aqueous Hypoestes rosea Leaf extract Ameliorates Lead-Acetate-Induced Thyroid Hormones Disruption in Albino Wistar Rats

F. K. Uwikor, B. E. Echonwere-Uwikor, O. E. Chukwuigwe-Igbere & O. E. Bamigbowu · Journal of Complementary and Alternative Medical Research · 2022

Aim: To evaluate the effect of aqueous extract of Hypoestes rosea (AEHR) leaf extract on thyroid hormones in lead-acetate-induced Albino Rats. Study design: Experimental study. Place and Duration of Study: Department of Pharmacology, University of Port Harcourt and Department of...

Open access Research Article 10.9734/jocamr/2022/v17i230330

Phytochemical and Antibacterial Profile of Moringa oleifera lam Seed Extracts on Some Wound and Enteric Bacterial Pathogens

George Okechukwu Anyanwu, Joy Nkeiruka Dike- Ndudim & Chizaram Winners Ndubueze · Journal of Complementary and Alternative Medical Research · 2022

The seeds of Moringa oleifera were studied in this research to determine the phytochemicals present and assess the antibacterial activities of the seed extracts against some wound and enteric bacterial pathogens. The extracts of Moringa oleifera seeds were obtained. The phytochem...

Open access Research Article 10.9734/jocamr/2022/v17i230329

Integrating In-silico with In-vitro Studies of Rutin as an Anti Hypertensive

M. Ganga Raju, N. V. L Suvarchala Reddy, M. Srivani & B. Pratyusha · Journal of Complementary and Alternative Medical Research · 2022

Rutin was evaluated for its antihypertensive effect by In vitro ACE inhibitory activity using Captopril as standard. For molecular docking the proteins namely PDB ID: 1UZE, 1O86, 2XY9 and 3L3N are selected and modelled. The abilities of the 3D model were assessed via the PROCHECK...

Open access Research Article 10.9734/jocamr/2022/v17i230326

Effect of Biochemical Parameters and Histology of Liver on Sucrose-Induced Metabolic Syndrome in Wistar Rats

U. Abubakar, H. I. Wasagu, M. O. Mohammed, R. I. Tsamiya, I. Mohammed, O. G. Avwioro, A. T. Muhammad, A. Umar, S. M. Sani, B. M. Yale, S. Umar & A. B. Imam · Journal of Complementary and Alternative Medical Research · 2022

Introduction: Metabolic syndrome (MetS) is a multiple factorial condition that draws a parallel to various risks such as dyslipidemia, hypertension, and hyperglycemia. As per the new International Diabetes Federation (IDF), for a person to be defined as having metabolic syndrome...

Open access Research Article 10.9734/jocamr/2022/v17i130324