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All published articles 773

Corchorus olitorius Extract Attenuate Isoproterenol-Induced Cardiac Injury via Inhibition of Oxidative Stress, Arrhythmia and Pro-Apoptotic Protein Bax Expression

Babatunde Adebola Alabi, Temidayo Olutayo Omobowale, Ademola Oyagbemi, Ileri-Oluwa Busayo Emmanuel, Adeolu Adedapo, Oluwole Fagbemi & Olugbenga Iwalewa · Journal of Complementary and Alternative Medical Research · 2020

Background and Aim: Corchorus olitorius (CO) leaf was reported to possess abundant antioxidants and used in the traditional treatment of heart disease. Previous studies revealed the protective roles of antioxidants against oxidative stress and inflammation, which are important un...

Open access Research Article 10.9734/jocamr/2020/v10i230159

Evaluation of Antioxidant Potentials of Ocimum gratissimum and Xylopia aethiopica in Alcohol- Induced Hepatotoxic Albino Rats

N. C. Chuks-Oguine, E. S. Bartimaeus & E. O. Nwachuku · Journal of Complementary and Alternative Medical Research · 2020

Aims: This study evaluated the antioxidant potentials of Ocimum gratissimum and Xylopia aethiopica on Alcohol-induced Hepatotoxicity in Albino rats. Study Design: The study is an experimental case-controlled study. Place and Duration of Study: This study was conducted at the Depa...

Open access Research Article 10.9734/jocamr/2020/v10i230158

Effects of Thymus schimperi and Moringa stenopetala Leaf Extracts on Lipid Peroxidation and Total Antioxidant Status in Pre-eclampsia Rat Models

Kumlachew Mergiaw, Yoseph A. Mengesha, Tesfaye Tolessa, Eyasu Makonnen, Solomon Genet, Abiy Abebe, Kidist Gebreyesus, Ashenif Tadele, Asfaw Debella & Demeke Ashencho · Journal of Complementary and Alternative Medical Research · 2020

Background: Hypertensive disorders of pregnancy (HDP) are common pregnancy complications, with a cumulative incidence of 7%. Pre-eclampsia (PE) is the most common clinical type of HDP and one of the five top leading causes of maternal mortality worldwide. There is imbalance betwe...

Open access Research Article 10.9734/jocamr/2020/v10i230157

Effect of a Slow-stroke Back Massage Combination and Frangipani Essential Oils against the Comfort of Menopause Sexual Relationship

Zaenal Amirudin, Afiyah Sri Harnany & Indar Widowati · Journal of Complementary and Alternative Medical Research · 2020

This study aims to analyze the effect of a combination of slow-stroke back massage (SSBM) and frangipani essential oils on the comfort of menopause women during sexual intercourse. The study with a quasi-equivalent non-control control group pre-test and post-test design. A sample...

Open access Research Article 10.9734/jocamr/2020/v10i130156

Neurohistological Study of the Interactive Influence of Ethanolic Leaf Extracts of Sida acuta and Rauvolfia vomitoria on the Hippocampus of Albino Rats

Kingsley A. Okon, Enobong I. Bassey, Iboro E. Edet & Grace U. Samuel · Journal of Complementary and Alternative Medical Research · 2020

Aim: To provide information on the interactive influence of Sida acuta and Rauvolfia vomitoria on the hippocampus of albino rats using neurohistological parameter. Methods: Thirty-five (35) female adult albino rats were used for the experiment. They were randomly divided into sev...

Open access Research Article 10.9734/jocamr/2020/v10i130155

Preliminary Phytochemical Screening of Five Plants as Possible Antileishmaniasis Control Agent

Mukhwana Dennis Wafula · Journal of Complementary and Alternative Medical Research · 2020

Leishmaniasis is a major public health problem globally and manifests in three clinical forms including visceral cutaneous and mucocutaneous. Visceral leishmaniasis is fatal if left untreated for a period of 2 years, while cutaneous leishmaniasis cause crusted papules or ulcers o...

Open access Research Article 10.9734/jocamr/2020/v10i130154

Anxiolytic Mechanism(S) and Corticosterone-Attenuating Effect of Hydroalcoholic Leaf Extract of Tapinanthus globiferus Mistletoe Growing on Azadirachta indica Tree

A. M. Umarudeen & M. G. Magaji · Journal of Complementary and Alternative Medical Research · 2020

Similar pharmacodynamic mechanism(s) often underlie drug actions and toxicities of anxiolytic agents and medicinal extracts. Extracts of Tapinanthus globiferus and related plant species have been reported with anxiolytic activities. But mechanistic evaluations on these plant extr...

Open access Research Article 10.9734/jocamr/2020/v10i130153

Mangifera indica (Mango) Bark Therapy Potentiates Wound Healing in Diabetic Rats

Rotimi Sunday Ajani & Opeyemi Jeremiah Olateju · Journal of Complementary and Alternative Medical Research · 2020

Objective: One of the debilitating complications of diabetes mellitus is chronic foot ulcer. Mangifera indica (Mango) is a naturally occurring and widely cultivated plant with many health benefits attributable to its parts. The wound healing potential of its bark in adult diabeti...

Open access Research Article 10.9734/jocamr/2020/v10i130152

A Mini Review on the Phytochemistry, Toxicology and Antiviral Activity of Some Medically Interesting Zingiberaceae Species

Clément M. Mbadiko, Clément L. Inkoto, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Aristote Matondo, Domaine T. Mwanangombo, Etienne M. Ngoyi, Gédéon N. Bongo, Clarisse M. Falanga, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · Journal of Complementary and Alternative Medical Research · 2020

Background: Plants of the Zingiberaceae family namely Curcuma longa, Aframomum melegueta and Zingiber officinale are known for their many biological activities such as the antiviral activity. Aim: To provide an updated knowledge on the phytochemistry, toxicology and antiviral act...

Open access Research Article 10.9734/jocamr/2020/v9i430150

Assessment of the Antioxidant Potential of Hypoestes rosea Leafin Streptozotocin-induced Diabetic Albino Rats

P. E. Africa, D. G. Tamuno Emine, E. O. Nwachuku & E. S. Bartimaeus · Journal of Complementary and Alternative Medical Research · 2020

Aims: The present paper was to investigate possible antioxidant actions of Hypoestes rosea leaf extracts in streptozotocin-induced diabetes mellitus in rats. Study Design:  This study is an interventional study. Place and Duration of Study: This study was conducted in the animal...

Open access Research Article 10.9734/jocamr/2020/v9i430149

Chemical Fingerprinting of Nauclea latifolia, an Antidiabetic Plant, Using GC-MS

Bob I. A. Mgbeje & Caroline Abu · Journal of Complementary and Alternative Medical Research · 2020

Aim: Earlier studies have established the antidiabetic activity of Nauclea latifolia. The aim of this study was to obtain chemical fingerprints of the ethanolic extracts of Nauclea latifolia leaf using Gas chromatography-Mass spectrometry (GC-MS), in order to assure proper identi...

Open access Research Article 10.9734/jocamr/2020/v9i430148

Factors Favoring Non-compliance of Treatment to People Living with HIV/AIDS in General Reference Hospital of Gbadolite, Nord Ubangi, Democratic Republic of the Congo

Kohowe Pagerezo Seraphin, Gédéon Ngiala Bongo, Kumbali Ngambika Guy & Koto-Te-Nyiwa Ngbolua · Journal of Complementary and Alternative Medical Research · 2020

Background: ART is one of the important pillars of the fight against AIDS. It restores immunity and reduces the risk of death. Its success lies in its strict compliance while its non-compliance exposes to the risk of resistance and therapeutic failure. The objective of this study...

Open access Research Article 10.9734/jocamr/2020/v9i430147

Ameliorative Effects of Ascorbic Acid and Allium sativum (Garlic) Ethanol Extract on Renal Parenchyma of Gentamicin-induced Nephropathic Rats

Dayo Rotimi Omotoso & Joy Motunrayo Olajumoke · Journal of Complementary and Alternative Medical Research · 2020

To assess ameliorative effects of Ascorbic acid (AA) and Allium sativum ethanol extract (ASEE) on renal parenchyma of gentamicin-induced nephropathic rats. Thirty Wistar rats (weighing between 180-205 g) were randomly divided into five groups (A-E).  These include Group A adminis...

Open access Research Article 10.9734/jocamr/2020/v9i430146

Anti-hyperglycaemic, Anti-dyslipidaemic and Hepatoprotective Effects of the Polyherbal Mixture Diarth in Alloxan-induced Diabetic Rats

Ojoye N. Briggs, Kemzi N. Elechi-Amadi, Chrissie Okobia & Ferdinand C. Ezeiruaku · Journal of Complementary and Alternative Medical Research · 2020

Aim: This study evaluates the anti-hyperglycaemic, anti-dyslipidaemic and hepatoprotective effects of the polyherbal mixture diarth, in alloxan-induced diabetic rats. Methodology: A total of 35 male Wistar albino rats weighing between 120-140 g were used for this study. Diabetes...

Open access Research Article 10.9734/jocamr/2020/v9i330145

Proximate, Phytochemical and Vitamin Compositions of Cucumis metuliferus (Horned Melon) Rind

Achikanu Cosmas Ezekaibeya, Ani Onuabuchi Nnenna & Onyishi Chukwuebuka Kenechukwu · Journal of Complementary and Alternative Medical Research · 2020

Cucumis metuliferus also known as horned melon is a plant belonging to the Cucurbitaceae family which has been reported to have medicinal value. Every part of the plant is consumed, except the rind, although edible is mostly discarded as waste. Solid food waste contributes to gre...

Open access Research Article 10.9734/jocamr/2020/v9i330144