Telfairia occidentalis Hook (Cucurbitaceae) is used in Ibibio ethnomedicine for the treatment of diverse diseases such as malaria, diabetes and gastrointestinal disorders. Evaluation of subacute administration of ethanol stem extract of Telfaira occidentalis for effect on hemato...
Open access
Research Article10.9734/ajbgmb/2025/v17i2440
The present study investigates the morphological, molecular, osteological, and evolutionary aspects of freshwater Bagrid catfish in the Western Ghats of India, focusing on the Cauvery River basin. Samples from three genera of the Bagridae family, namely Hemibagrus, Sperata, and M...
Open access
Research Article10.9734/ajbgmb/2025/v17i2438
There appeared not to have been a way of linking pre-zero-order kinetics to zero-order kinetics so as to garner key kinetic parameters at very high industrial concentrations of the substrate. The objectives were the derivation of equations that can be explored in relating pre-zer...
Open access
Research Article10.9734/ajbgmb/2025/v17i1437
Telfairia occidentalis Hook (Cucurbitaceae family) is a pumpkin widely used for dietary purposes and in traditional healthcare by Ibibios of Nigeria, as remedy for various diseases such as malaria, diabetes, pains among others. Telfairia occidentalis stem extract and fractions...
Open access
Research Article10.9734/ajbgmb/2025/v17i1436
In recent years, herbal plants have been widely used in the treatment of neurodegenerative diseases. Centella asiatica (l.) urb is a significant medicinal plant renowned for its diverse ethnomedicinal applications. The present study evaluated biological activities for neuroprotec...
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Research Article10.9734/ajbgmb/2025/v17i1435
Farida Jazuli Usman, Dikshat Gopal Gupta, Sarki A Abdulkadir, Ibrahim Muhammad Usman, Adamu Jibrin Alhassan, Young A Yoo, Haris Jaafar Bello, Binta G. Kurfi & Kamaluddeen Babagana·Asian Journal of Biochemistry, Genetics and Molecular Biology·2025
Despite advancements in the treatment of advanced prostate cancer, including metastatic castration-resistant prostate cancer (mCRPC), the disease remains lethal, often developing resistance to conventional therapies such as androgen deprivation therapy (ADT) and chemotherapy. The...
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Research Article10.9734/ajbgmb/2025/v17i1434
Introduction: Cancers are a real public health problem. Their prevalence varies greatly among the world population and many therapeutic strategies, such as chemotherapy, have been put in place and most chemotherapy protocols are based on products containing fluoropyrimidines. How...
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Research Article10.9734/ajbgmb/2025/v17i1433
Anti-retroviral (ARV) drugs are medications used for the treatment of diseases caused by retroviruses, primarily HIV. HIV/AIDS is a condition in human in which the immune system starts to fail, resulting to life threatening opportunistic infections. This study investigated the ef...
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Research Article10.9734/ajbgmb/2025/v17i1432
Testosterone plays a crucial role in various aspects of reproductive health and general well-being. Herbal extracts are commonly believed to have potential effects on testosterone levels. This study aimed to explore the impact of hot aqueous extracts of Cyperus esculentus latvum...
Open access
Research Article10.9734/ajbgmb/2024/v16i12430
HIV/AIDS is a condition in human in which the immune system begins to fail, leading to life threatening opportunistic infections. This study investigated the effect of first and second line fixed-dose combination (FDC) antiretroviral drugs on some biochemical parameters in Wistar...
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Research Article10.9734/ajbgmb/2024/v16i12431
Testosterone influences various aspects of reproductive health and overall well-being. Herbal extracts are reputed for their potential effects on testosterone levels. This study investigated the testosterone-modulating potentials of hot aqueous extracts of Telfairia occidentalis...
Open access
Research Article10.9734/ajbgmb/2024/v16i12429
Lawrence John AJutor, Okabeonye Sunday Agbo, Christian Ajiri Adobor, Blessing Aitebiereme Iyoyojie, Kingsley Ugonna Ugoagwu, Oghenevware Manawa, Osaruese Faluyi, Emmanuel Oluwasegun Ismaila, Oluchi Esther Ugwuanyi & Adepeju Matilda Adekoya·Asian Journal of Biochemistry, Genetics and Molecular Biology·2024
Gene editing has emerged as a transformative approach in cancer immunotherapy. Several gene editing tools have been employed for precise modification of the DNA of immune cells, enhancing their ability to target and eliminate cancer cells. This review examines the evolution and a...
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Research Article10.9734/ajbgmb/2024/v16i12428
Aim: To evaluate Single Nucleotide Polymorphism and Allele frequencies of some genetic variants among T2DM subjects in Port Harcourt. Study Design: Cross-sectional Study. Place and Duration of Study: Port-Harcourt, Nigeria, Inqaba Biotec (molecular analysis) and Evashalom Medical...
Open access
Research Article10.9734/ajbgmb/2024/v16i12426
Aim: To evaluate the influence of some variants of SLC22A1 and CYP2C9 genes on glycaemic response in T2DM subjects on metformin/Sulphonylureas combination therapy in Port Harcourt. Study Design: Cross-sectional Study. Place and Duration of Study: Port-Harcourt, Nigeria, Inqaba Bi...
Open access
Research Article10.9734/ajbgmb/2024/v16i12427
Background: Pigeon pea is an economical source of natural antioxidants and its use could be a means of attaining prospect in ensuring food safety. This in vitro study intends to compare the primary constituents and oxidation inhibition potentials of peeled pigeon pea (PPP) and un...
Open access
Research Article10.9734/ajbgmb/2024/v16i12424