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All published articles 550

Evaluation of Gender-Specific Variation in Lead-Induced Hepatotoxicity in Wistar Rats

Lawal Onaopepo Abdulwakeel, Ige Serah Funke, Alabi Inioluwa & Owolabi Gbenga Opeyemi · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

The heavy metal lead is toxic and triggers oxidative stress mediated toxicity in many organs, including the liver. This study aimed to evaluate the gender-specific variation in lead-induced hepatotoxicity in wistar rats. 10 male and 10 female Wistar rats (180-220g) were each divi...

Open access Research Article 10.9734/ajbgmb/2024/v16i10410

HLA-B27 Frequency and its Association with Ankylosing Spondylitis in Indian Population: A Multi-City Analysis from a Single-Center Study

Vandana Sharma, Sanjay Kumar, Rahul Katara, Shivani Sharma, Vipin Kumar, Namrata Pandey, Satish Kumar Singh, Shashikant Verma, Sachin Kumar & Ranvijay Prasad · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

The human leukocyte antigen HLA-B*27 is a Class 1 antigen of the major histocompatibility complex (MHC) with B locus and has been established in association with pathogenesis of Ankylosing Spondylitis (AS) since 1973. AS is a multifactorial disease which occurs due to interaction...

Open access Research Article 10.9734/ajbgmb/2024/v16i10408

Effects of Citric Acid on the Phytoextraction Potential of Psium sativium L Grown on Heavy Metals Contaminated Soil

Nkwocha John Nnaemeka, Nwauche K. T. & Amadi B. A. · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

This study assessed the effect on citric acid on the phytoextraction of Psium sativium on heavy metals. The experiment was an outdoor experiment which was done using soil samples obtained from auto-mechanic workshop. The soil sample was analysed for the presence of heavy metals a...

Open access Research Article 10.9734/ajbgmb/2024/v16i10407

Pharmacognostic Study and Phytochemical Profilling of Dichloromethane Extracts of the Leaf and Stem of Vernonia conferta Benth and Vernonia colorata Drake Asteraceae

Uwemedimo Francis Umoh, Ogechi Innocentia Obasi, Imoh Imeh Johnny, Mathias N. Igwe & Victor Chubueze Onyido · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Aims: The study determines various taxonomic, pharmacognostic and phytochemical standards helpful to ensure the identity, purity, safety and efficacy of Vernonia colorata and Vernonia conferta. Study Design: To study these two species of Vernonia for their epidermal cell shapes,...

Open access Research Article 10.9734/ajbgmb/2024/v16i9406

Effects of the Anti-Inflammatory Properties of Bitter Leaf (Vernonia amygdalina) Ethanolic Extract on Streptocuccus Pyrogenes Induced Wister Rats

Unoh Florence Ben & Chinyere Osondu Anyanwu · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Aim: To investigate the effectiveness of V. amygdalina leaf extract on the remediation of the cytological and physiological damages on albino rats caused by streptococcus pyogenes. Study Design: Randomized Controlled Trial (RCT) design with multiple treatment groups. Research was...

Open access Research Article 10.9734/ajbgmb/2024/v16i9405

Modulatory Effect of Aqueous Ginger (Zingiber officinale) Extract on Gentamicin Sulfate Induced Oxidative Stress and Nephrotoxicity in Female Albino Rats

Henry Wealth Oyarieme, Akinniyi Adediran Osuntoki, Holiness S.A. Olasore, Ogheneovo Obros, Jeromi Otiti & Zakariyah Abdullahi Abiodun · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Acute renal failure is a common complication of gentamicin, an aminoglycoside antibiotic widely used against gram-negative infections, often mediated by oxidative stress. This study investigates the potential protective effects of aqueous ginger extract against gentamicin-induced...

Open access Research Article 10.9734/ajbgmb/2024/v16i9404

Improving Food Safety in Africa Using Cutting-Edge Biotechnology & Molecular Biology Approaches

Yusuf Alhassan, Abdullahi Olanrewaju Ajadi, Oni Gbotemy Jerry, Ahmed Wopa Wurie & Temitope Esther Olajide · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Ensuring food safety in Africa is a critical challenge that requires innovative approaches. Food safety is a pressing concern in Africa, where the prevalence of foodborne diseases and contamination poses significant health and economic challenges. This review explores the potenti...

Open access Research Article 10.9734/ajbgmb/2024/v16i9403

The Tale of Warrior Gene: The MAOA-upstream Variable Number Tandem Repeat (MAOA-uVNTR) Polymorphism and Its Role in Shaping Aggressive and Violent Behaviour

Minasha R Abeykoon, Chanika D Jayasinghe, Ruwan J Illeperuma & Thelma Abeysinghe · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

The Monoamine Oxidase A (MAOA) gene has acquired significant attention across the field of behavioral genetics over time due to its association with different adverse impacts it has had on altering human behavior. Research suggests that specific genetic variations of the MAOA gen...

Open access Research Article 10.9734/ajbgmb/2024/v16i9402

Peroxidase Activity in Extracts of Watermelon Pulp: Effects of Ethylenediaminetetraacetic Acid and Some Cations

Iniaghe, O.M & Ohilebo A.A · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Aim: The aim of this study was to evaluate the effects of EDTA and some chloride salts of Ca, Cr, Fe and Mg on the initial velocity (Vo) of crude peroxidase from the pulp of watermelon. Study Design: The study design is In vitro enzyme assay. Place and Duration of Study: This stu...

Open access Research Article 10.9734/ajbgmb/2024/v16i8401

Effects of Eleophorbia drupifera Leaves Extract on Some Biochemical and Haematological Parameters of Albino Rats

Nyah, Nkereuwem U., Obosi, Ekemini J., Ekong, Udeme, J., Ukpong, Etiowo G & Chukwuemeka, Iheanyichukwu E · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Water and ethanol-water extracts of Eleophorbia drupifera leaves were administered orally in graded doses of 0.5ml (147.06mg/kg body weight), 1.0ml (303.3 mg/kg body weight) water extract and 0.5ml (157.66 mg/kg body weight), 1.0ml (301.72 mg/kg body weight) ethanol-water extract...

Open access Research Article 10.9734/ajbgmb/2024/v16i8400

Genetic Differentiation of Indian Zebu Cattle (Bos tauraus) Breeds Using Random Oligonucleotide Primers (RAPD-PCR) in Amravati Region, Maharashtra, India

Nilima J. Tayde, Hemlata P. Nandurkar & Nandakishor E. Warghat · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

In India, insufficient characterization skills and extensive crossbreeding of cattle have led to the loss of several breeds. The purpose of this work is to find polymorphic primers for identifying Zebu cattle breeds. Random crossbreeding has resulted in genetic losses among the G...

Open access Research Article 10.9734/ajbgmb/2024/v16i8399

Antimicrobial Resistance and Phenotypic Detection of Extended Spectrum Beta-Lactamase in Escherichia coli from Children with Cases of Diarrhea in Nasarawa-South, Nasarawa State, Nigeria

Zakou AT, Ngwai YB, Nkene IH, Ishaleku D, Abimiku RH & Ekeleme IK · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Aims: This study investigates the antimicrobial resistance and phenotypic detection of extended-spectrum beta-lactamase in Escherichia coli from children with cases of diarrhea in Nasarawa-south, Nasarawa State, Nigeria. Place and Duration of Study: Nasarawa South, Nigeria, in 20...

Open access Research Article 10.9734/ajbgmb/2024/v16i8398

Emerging Role of Probiotics in Advancement of Combating Physical Abnormalities and Diseases: A Systematic Perspective Analysis

Mst. Tania Khatun, Forkanul Hoque, Naeema Salatia Hoque, Md. Sakhawat Hossain, Md. Ashraful Alam, Sabrina Afrin, Tanjina Nasrin Eva & Rahima Tanbin Tama · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Probiotics are live microorganisms, primarily bacteria that give the host health benefits when given in sufficient amounts. It works in various defensive mechanisms, including releasing antimicrobial compounds, competitive adhesion to the mucosa and epithelium, fortifying the gut...

Open access Research Article 10.9734/ajbgmb/2024/v16i8397

Spectral Characterization of Canarium ovatum Engl. (Pili) Pulp Extract from Allen, Northern Samar, Philippines

Harley Nico L. Jazmin, Flyndon Mark S. Dagalea & Karina Milagros Cui-Lim · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Canarium ovatum (Pili) Pulp was widely cultivated in the town of Allen, Northern Samar, Philippines. In Allen, Northern Samar produces 60 to 100 kilograms per year every tree. The pili can used in various aspects like oil and soap production, fuel, sweet candies and bread stuffin...

Open access Research Article 10.9734/ajbgmb/2024/v16i7396

Effect of Garcinia Kola in Ivermectin-Induced Toxicity in the Hematology of Treated Rats (Rattus Novergicus)

Benjamin Nnamdi Okolonkwo, Godspower Ikechi Achi, Erasmus Martha A, Suama Promise, Patrick Williams, Osuosa Atoukaritou & Esther Okagbe Ogbugo · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Garcinia kola (GK) is prized in African herbal medicine for its diverse uses, including social, economic, and medicinal purposes. This study examined the dose-dependent toxicity of ivermectin and the protective effects of Garcinia kola extract on the hematological parameters of W...

Open access Research Article 10.9734/ajbgmb/2024/v16i7395