Untreated wastewater discharge into waterbodies poses a number of risks, including the potential for aquatic organisms' DNA to be damaged. Using the comet assay, this study assessed the genotoxic impact of cassava wastewater on the gonads, liver, and gills of post-juvenile Claria...
Open access
Research Article10.9734/ajbgmb/2024/v16i7394
The analysis of the leaf extract of Chromolaena odorata was carried out to characterize its components, GC-MS analysis was carried out in our laboratory. The spectrum obtained showed 15 peaks which translates to 15 compounds, with their molecular weight, formula and structures. I...
Open access
Research Article10.9734/ajbgmb/2024/v16i7393
The epidermal growth factor receptor (EGFR) protein tyrosine kinase (PTK) is a crucial target in the pursuit of anti-tumor drug discovery. This study investigates 305 phytochemicals from five known anticancer plants (Anacardium occidentale, Annona muricata, Spondias mombin, Ocimu...
Open access
Research Article10.9734/ajbgmb/2024/v16i7392
Background: The oxidative deamination of amines and neurotransmitters as typified by the action of monoamine oxidase (MAO) is known to be involved in psychological disorders, oxidative stress, and many other adverse pharmacological reactions. A new series of studies have been gea...
Open access
Research Article10.9734/ajbgmb/2024/v16i7391
This study evaluated the chemical composition and the effect of ethanolic extract of Persea americana pulp on caffeine induced oxidative stress on male wistar rats. Forty-five (45) mature male rats were used and divided into five (5) groups of nine (9) rats per group. Group two (...
Open access
Research Article10.9734/ajbgmb/2024/v16i7390
Olajumoke B. Oladapo, Toheeb A. Jumah, Justine U. Egbe, Jude O. Uzoechina, Aderonke E. Fakayode, Muhammad I. Adeyemi, Oluwaseyi P. Olaniyan, Chimunda A. Solomon, Zion O. Oluwasegun, Damilola M. Olatunde, Uche O. Arunsi, Samuel O. Olubode, Precious A. Akinnusi, Toheeb A Balogun & Sunday B. Akinde·Asian Journal of Biochemistry, Genetics and Molecular Biology·2024
Cancer is the second leading cause of mortality worldwide. The strictly controlled physiological process of apoptosis is required for immune system function, maintenance of tissue homeostasis, and appropriate embryonic development. Anti-apoptotic proteins such as Bcl-xL and Mcl-1...
Open access
Research Article10.9734/ajbgmb/2024/v16i7389
India has a world's richest, most abundant and most promising inland fisheries resources with variety fishes in tributaries, streams, canals, lakes, ponds, and reservoirs. There are several significant river systems in India, including the Cauvery, Tapi, Narmada, Krishna, Indus,...
Open access
Research Article10.9734/ajbgmb/2024/v16i7388
The qualitative study of secondary metabolites of the root and stem bark of Crossopteryx febrifuga Benth, Khaya anthotheca, Gardenia ternifolia, and Terminalia glaucescens obtained by maceration were estimated by tub reaction. Antimicrobial and cytotoxic activities of the root an...
Open access
Research Article10.9734/ajbgmb/2024/v16i7387
The study was aimed at investigating the effect of ethanol leaf extract of Lantana camara on the fasting blood glucose, body weight and kidney function indices of alloxan-induced diabetic albino Wistar rats. Thirty male albino Wistar rats of weight 100-181 g were randomly assigne...
Open access
Research Article10.9734/ajbgmb/2024/v16i6386
The prevalence of iodine deficiency disorders remains a challenge in numerous developing nations despite widespread advocacy for iodized salt and iodine-fortified foods. As a result, this study assesses the iodine content of ten selected vegetables—water leaf, okra, green, tomato...
Open access
Research Article10.9734/ajbgmb/2024/v16i6385
Sanchezia speciosa Leonard, Acanthaceae is used as ornamental plant. It used in folklore medicine in the management of pain, anti-microbial and insecticide. An investigation was carried out to evaluate the various taxonomic, pharmacognostic and phytochemical standards to ensure t...
Open access
Research Article10.9734/ajbgmb/2024/v16i6384
Background: Diabetes mellitus is a life-threatening disease associated with worsening of glycemic control, progressive metabolic dysfunctions and disruption of the Phosphatase and Tensin Homolog (PTEN) receptor. Purpose: To evaluate the effect of chloroquine on blood glucose lev...
Open access
Research Article10.9734/ajbgmb/2024/v16i6383
Objective: This study aimed to isolate and characterize a bacterium capable of degrading the pesticide paclobutrazol. The strain was obtained from soil enriched with paclobutrazol, and its degradation ability was assessed using gas chromatography (GC). Methods: A single strain wa...
Open access
Research Article10.9734/ajbgmb/2024/v16i6382
The use of herbal medicines has a very long history for therapeutic purposes. However, cases of toxicological effects have been reported. The present study aims to assess the safety level of herbal medicines by monitoring the organochlorine pesticide (OCP) residues content. This...
Open access
Research Article10.9734/ajbgmb/2024/v16i6381
Siam plant (Chromolaena odorata) is a plant with a characteristic aromatic smell, since ancient times, had been of interest for medical purposes in the local parlance and had been reported to be used in tradition medicine as antispasmodic, antiprotozoal, anti trypanosomal, antiba...
Open access
Research Article10.9734/ajbgmb/2024/v16i6380