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All published articles 550

Interleukin-6 and Ferritin as Prognosticators in SARS-CoV-2 Patients from Kashmir, North India

Iqra Farooq, Rafiqa Eachkoti, Masood Tanvir, Saleem Hussain, Sanah Farooq, Ifrah Jan, Sadaf Saleem & Sabhiya Majid · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2023

Background: Identifying early predictive biomarkers of disease severity and disease outcome is fundamental for the practical management of Covid -19 patients. Although prognostic value of several Pro- and inflammatory markers have been determined in different population studies,...

Open access Research Article 10.9734/ajbgmb/2023/v13i1287

First Report Occurrence of CIT and DHA AmpC β-lactamase Gene in Escherichia coli and Klebsiella pnuemoniae from Clinical Sample in South Eastern, Nigeria

Peace Oluchi Akpu, Henrietta Onyinye Uzoeto, Ikemesit Udeme Peter, Onyinye Lovette Nomeh, Agabus Chidiebube Nwuzo, Rebecca Chinenye Ogba & Ifeanyichukwu Romanus Iroha · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2023

Background and Objectives: Over time, the enzymes AmpC β-lactamases have become more significant, due to their roles in antibiotic resistance among enterobacteriaceace especially in Escherichia coli and Klebsiella pnuemoniae. Due to increase multidrug resistant express by AmpC β-...

Open access Research Article 10.9734/ajbgmb/2023/v13i1285

The Use of Dimethyl Biguanide as a Potential Treatment for Alzheimer's Disease in Rats

Hamed A. Abosharaf, Yasmin Elsonbaty, Ehab Tousson & Tarek M. Mohamed · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2023

Amis: Alzheimer’s disease (AD) is one of the most rapidly growing diseases in recent times. Despite extensive research to find an appropriate medicine, there has been no effective drug until now. Study Design: The present study was designated to investigate the therapeutic impact...

Open access Research Article 10.9734/ajbgmb/2023/v13i1283

Genetic Diversity and Phytochemical Studies on Selected Ecotypes of Utasi (Gongronema latifolium) Plant Using Microsatellite Markers

Nelson, Anita Y., Godwin M. Ubi & Egbaji Covenant · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2023

Diversity and phytochemical studies were carried out on twelve ecotypes of utasi, Gongronema latifolium using simple sequence repeats markers. Screening of ten (10) trinucleotide SSR primers, produced  4 primers that were able to amplify the DNA from all the plant ecotype. A tota...

Open access Research Article 10.9734/ajbgmb/2023/v13i1284

Heterosis and Estimation of General and Specific Combining Ability as Base for Selected Superior Recombination of the Some Crossed Cotton Genotypes

W. M. B. Yehia, A. M. Abdelbary, A. A. Mohamed, H. M. K. Kotb & M. M. Sherif · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2023

The objective of this study was to determine the general and specific combining abilities and heterosis of some cotton genotypes for yield, its components and fiber traits using line x tester mating design. Nine parents (six line and three testers) were crossed in a line x tester...

Open access Research Article 10.9734/ajbgmb/2023/v13i1282

Molecular Characterization of Carbapenemase Encoding Genes in Pseudomonas aeruginosa from Tertiary Healthcare in South Eastern Nigeria

Rebecca Chinenye Ogba, Onyinye Lovette Nomeh, Christiana Inuaesiet Edemekong, Agabus Chidiebube Nwuzo, Peace Oluchi Akpu, Ikemesit Udeme Peter & Ifeanyichukwu Romanus Iroha · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Background and Objectives: In recent years, the rate of carbapenemase encoding gene in P. aeruginosa has increased worldwide and has become of great concern since it’s significantly restricts the therapeutic options for patients in Tertiary health care. Therefore, there’s a need...

Open access Research Article 10.9734/ajbgmb/2022/v12i4281

Copper Oxide Nanoparticles Induced Liver and Kidney Toxicity in Rat

Afaf El-Atrash, Somia Zaki, Ehab Tousson & Marwa Negm · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Aims: Copper oxide nanoparticles (CuO NPs), which have potential hazards for organisms and the environment in a number of applications, have emerged as a prominent class of nanomaterials. Study Design: This study aimed to investigate the effect of copper oxide nanoparticles in ra...

Open access Research Article 10.9734/ajbgmb/2022/v12i4280

Ulcero-Protective Potential of Ethyl Acetate Fractions of Persea americana Seed and Bryophyllum pinnatum Leaf Binary Combinations in Indomethacin Induced Gastric Ulcer

Emeka S. Asiwe, Chidi U. Igwe, Kizito M. E. Iheanacho, Viola A. Onwuliri, Chinwe S. Alisi, Nmadike G. Ezeji-Chigbu & Cosmas O. Ujowundu · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Aims: This study was aimed at investigating the protective potential of ethyl acetate fractions of Persea americana (PA) seed and Bryophyllum pinnatum (BP) leaf binary combinations against indomethacin-induced gastric ulcers. Methodology: Fifty (50) male Wistar rats were used in...

Open access Research Article 10.9734/ajbgmb/2022/v12i4279

Effects of Two Months Durational Vitamin E Therapy on Paraquat-inflicted Liver Damage in Wistar Rats (Rattus norvegicus)

Benjamin Nnamdi Okolonkwo · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Paraquat is a highly poisonous chemical that is commonly used as a herbicide (plant killer) to control weeds and grasses. It has been found to disrupt the levels and activities of some liver enzyme parameters. This experimental study was aimed at assessing the effect of Vitamin E...

Open access Research Article 10.9734/ajbgmb/2022/v12i4277

The Effect of Combined Vitamin Treatment on Paraquat-inflicted Liver Damage

Benjamin Nnamdi Okolonkwo · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Paraquat poisoning causes serious herbicide intoxication commonly and usually as a result of deliberate or accidental ingestion. Vitamins C and E are very good antioxidants that reacts rapidly with radicals and alters lipid peroxidation. This study was done to evaluate the effect...

Open access Research Article 10.9734/ajbgmb/2022/v12i4278

Antitoxic Effects of Solanum betaceum cav. Peel Skin Extract

Janti Sudiono, Pretty Trisfilha & Debi Agita · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Background: In Indonesia, Solanum betaceum cav is a traditional herbal medicine which their skin is often wasted because not many people known its content. Aims: To find out the anti-toxic effect of Solanum betaceum cav peel skin ethanol extract on rat’s renal post-carrageenan in...

Open access Research Article 10.9734/ajbgmb/2022/v12i4276

Chromium Induced Developments of Diseases and their Inhibitions by Cargos

Ardhendu Kumar Mandal · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

The exposure of hexavalent chromium (Cr-VI) mainly through the inhalation, skin contact or oral administration by the environmental chromium industrial processes causes the major toxicity-induced health hazardous mortality throughout the world. Though reduced chromium (Cr-III), a...

Open access Research Article 10.9734/ajbgmb/2022/v12i4274

The Trace Elements of Drinking Water and Longevity Phenomenon

Alexandra Esther Ortega Vilches · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

The review explores how the level of trace element intake and its retention influence life expectancy and centenarian longevity of the blue zones (longevity hot spots) in Mayang, China in comparison to Ikaria Island. Both Mayang City in China and Ikaria Island have the greatest p...

Open access Research Article 10.9734/ajbgmb/2022/v12i4273

Biochemistry of Corona Virus: An Overveiw

Nwaogwugwu Joel Caleb, Victor Chukwubuike Nwankwo, Nweke Celestine Chimaobi, Ugoaghalam Uche James, Uchenna Samuel Igwe, Aguwamba Chinedu & Faith Nwokoma · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Coronaviruses forma large family of respiratory viruses having positive (+ve)-stranded RNA (C0V).  Their names are derived from the crown-like shape that is present on their them (surface). The new viral strain SARS-CoV-2 was first discovered in Wuhan, China, in December 2019. Ev...

Open access Research Article 10.9734/ajbgmb/2022/v12i4272

Adherence to Antiretroviral Therapy (Art) among Pregnant Women Living with HIV/AIDS in Okigwe Imo State, Nigeria

E. C. Uloeme, Nwaogwugwu Joel Caleb, Victor C. Nwankwo & C. I. Nosiri · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

The antiretroviral medication (ART) compliance of expectant HIV/AIDS patients in Nigeria's Okigwe Imo state was investigated in this study. In particular, the study established the prevalence of HIV among expectant mothers in Okigwe Imo State, Nigeria, identified the behavioral a...

Open access Research Article 10.9734/ajbgmb/2022/v12i4271