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All published articles 550

Evaluation of the Effect of Working Hours on Haematological Parameters among Cement Loaders in Port-Harcourt

Jonathan Nyebuchi, Collins Ohwonigho Adjekuko, Adams Matthew Okur, Stella Urekweru Ken-Ezihuo & Mieiwari Ibifubara Jumbo · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Cement dust exposures has been reported to result in significant occupational health problems and long term complications and symptoms. This study was aimed at assessing the impact of work hours on haematological parameters of cement workers. 100 cement loaders were selected in a...

Open access Research Article 10.9734/ajbgmb/2022/v12i130286

An Extensive Review on the Development of Plant-Based Vaccines against SARS-Cov-2 and Respiratory Disorders Using Plant Biotechnology Platform

Priyanka Samanta & Pratik Chatterjee · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

The COVID-19 pandemic is the most recent of numerous pathogenic viral pandemics that have posed risks to global health. Its exponentially expanding global transmission is placing pressure on the global health system. There are currently a large number of COVID-19 candidate vaccin...

Open access Research Article 10.9734/ajbgmb/2022/v12i130285

GC-MS Analysis and Antiplasmodial Potentials of Bioactive Compounds Present in Methanolic and Ethanolic Leaf Extracts of Daniella oliveri

Muhammed Muazu, Abdulsalami Mohammed Sani, K. B. Dikwa, D. M. Dibal, Kokori Bajeh Tijani & Junaidu Yahaya · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Qualitative, quantitative and Gas Chromatography-Mass Spectrometry (GC-MS) analysis are useful for the determination of bioactive components necessary for accessing the antiplasmodial potentials of methanolic and ethanolic leaf extracts of Daniella oliveri (D. oliveri). The aim o...

Open access Research Article 10.9734/ajbgmb/2022/v12i130284

Hepatoprotective Effect of Methanol Stem Bark Extract of Diospyros mespiliformis against Carbon Tetrachloride Induced Liver Damage

J. Nwaogu, I. M. Fakai & I. Yahaya · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Aim: This study evaluated the hepatoprotective effects of methanol stem bark extract of Diospyros mespiliformis against carbon tetrachloride-induced liver damage in albino rats. Methodology: Acute toxicity study was determined using limit fixed dose test of 5000mg/kg for 14 days....

Open access Research Article 10.9734/ajbgmb/2022/v12i130283

Influence of Sacoglottis gabonensis Ethanolic Extract on the Electrolytes of Swiss Mice Administered Aspartame

Aruchi, Wekhe-Emenike, Adetutu Olubunmi Obulor & Eme Efioanwan Orlu · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Aim: This study aimed at evaluating the influence of Sacoglottis gabonensis ethanolic extract on the electrolytes of swiss mice administered aspartame. Location and Duration of Study: The study was carried out in the green house of the Department of Animal and Environmental Biolo...

Open access Research Article 10.9734/ajbgmb/2022/v11i430281

Association of LPAR1 Gene Variants with Type 2 Diabetes in Local Population

Waseem Raza, Bushra Rao, Syeda Zahra Abbas, Syeda Tahira Qousain Naqvi & Syed Aun Muhammad · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Type 2 diabetes mellitus (T2DM) is the most prevailing worldwide health challenge of the 21st century and the 5th leading cause of death worldwide. About 90% of diabetic patients are diagnosed as having T2DM. LPAR1 gene codes LPA protein that is involved in the regulation of many...

Open access Research Article 10.9734/ajbgmb/2022/v11i430279

The Prevalence of Hepatitis B Virus Infection among Patients Attending Defence Headquarters Medical Centre, Asokoro, Abuja, Nigeria

J. O. K. Abioye, Agi Mathias Omojo & Olokun Alexander Lanzema · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Hepatitis B infection is a global public health problem and is endemic in sub Saharan Africa. This disease has different modes of transmission and the infection is usually common in developing countries, including Nigeria. This study was carried out to determine the prevalence of...

Open access Research Article 10.9734/ajbgmb/2022/v11i430277

Evaluation of Antiplasmodial Activity of Solvents Extract of Senna occidentalis Leaves

Muhammad Ibrahim Usman & Abubakar Bilyamini Maazu · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

The high rate of resistance to an antimalarial drug suggests the importance to discover new compounds with potential antimalarial activities. This research work is aimed at evaluating the antimalarial activity as well as characterization of potential bioactive compounds from extr...

Open access Research Article 10.9734/ajbgmb/2022/v11i430276

Serum Levels of Some Nutritional, Hepatic and Renal Markers in Third Trimester Pregnant Women

Oyewale Thomas Oyediran, Rashidat Abidemi Oladiti, Gregory Uchechukwu Joseph & Ayobola Abolape Iyanda · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Purpose: Nutritional status, before and during pregnancy, is a strong determinant of health outcomes in the mother and newborn, and can affect the foetal structure, physiology and metabolism. Maternal health, hepato-renal function, as well as calcium and magnesium levels during p...

Open access Research Article 10.9734/ajbgmb/2022/v11i430272

Comparative Chemical Evaluation of Three Species of Melon (Cucumis melo, Cucurbita moschata and Cucumeropsis mannii) Seeds

Y. Y. Ajibe, M. A. Ubana & T. O. Bamidele · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Aim: This study evaluates the nutritional composition of three species of melon seeds (Cucumeropsis mannii, Cucumis melo, and Cucurbita moschata). The seeds were obtained from Nasarawa State, Nigeria. Methodology: Phytochemical constituents and proximate composition was determine...

Open access Research Article 10.9734/ajbgmb/2022/v11i330271

Lethal dose Examination and Effect of Different Part Extracts of Ageratum conyzoides L on Hematology and Serum Electrolytes of Streptozotocin Induce Diabetic Rats

G. Istifanus, C. D. Luka & T. O. Johnson · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Diabetes mellitus (DM) is a disease condition caused by decreased insulin production in the pancreas or as a result of the inability of insulin to act on target tissues that activate the absorption of blood glucose. This subsequently leads to an increased concentration of glucose...

Open access Research Article 10.9734/ajbgmb/2022/v11i330270

The Demographical Prevalence of Malaria in Pregnant Women in Oshimili South Local Government Area of Delta State, Nigeria

S. O. Kehinde, C. C. Ukoha & C. C. Ezemba · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

This study evaluated the prevalence of malaria in pregnant women attending antenatal clinics in Delta state. Thick-film microscopy was used to detect parasitaemia while polymerase chain reaction (PCR) was employed to confirm positivity. Statistical method used were Chi square, Pa...

Open access Research Article 10.9734/ajbgmb/2022/v11i330269

Microbial Assessment of Indoor Air of the Applied Microbiology Laboratory, Nnamdi Azikiwe University, Awka, Nigeria

A. S. Ezemba, C. M. Nwabisi, I. O. Udemezue, O. J. Osuala, E. M. Ezeokoli & C. C. Ezemba · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Air is made up of enormous number of microorganisms mainly fungi and bacteria spore. Their estimation is important as an indication of cleanliness of any particular environment. The present study was carried out to assess microorganisms in indoor air of Applied Microbiology labor...

Open access Research Article 10.9734/ajbgmb/2022/v11i330268

Regulatory Role of DNA Methylation and Its Significance in Plants

Rao Saad Rehman, Mujahid Ali, Syed Ali Zafar, Hassan Bashir, Asad Nadeem Pasha, Abdullah Javed, Naveed Ali Ashraf & Waqar Ali Shah · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

DNA methylation is a well-known epigenetic modification that is essential for gene regulation and genome stability. Anomalies in plant development can result from aberrant DNA methylation patterns. DNA methylation is much more important in plants with more complicated genomes whe...

Open access Research Article 10.9734/ajbgmb/2022/v11i330267