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All published articles 550

Comparative Study of the Effect of Aqueous Extract of Entandrophragma angolense and Vitamin B12 on Induced Hemolytic Anemia and Inflammation in the Wistar Rat

Adeoti, Franck Mansour, Yenon, Achiè Aurélie, Vanie, Bi Foua Jonas, Alain, Dit Philippe Bidié & Djaman, Allico Joseph · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

Entandrophragma angolense is a plant of the family Meliaceae of African pharmacopoeia. It is used in traditional medicine as an analgesic and anti-inflammatory in cases of abdominal or hips pain. The aim of this study is to compare the effect of oral administration of aqueous ext...

Open access Research Article 10.9734/ajbgmb/2019/v2i130053

Cytotoxicity of N-(P-chlorophenyl)-7-hydroxycoumarin -3-yl carboxamide and Ethyl 7-hydroxycoumarin-3-yl Ester

A. S. Tmamm, F. Z. Mohammed & I. M. El-Deen · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

Background: Coumarins (2H-1-benzopyran-2-one), an important class of heterocyclic compounds, and its derivatives can be found in many natural or synthetic drug molecules and possess versatile bioactivities making them important molecules for medical practitioners and medicinal ch...

Open access Research Article 10.9734/ajbgmb/2019/v2i130052

Dose-Dependent Chemopreventive Effect of Methanol Extract of Carica papaya Seed on Potassium Bromate- Induced Nephrotoxicity in Rats

M. A. Kanadi, A. M. Wudil, A. J. Alhassan, A. L. Ngwen, A. I. Yaradua & A. Nasir · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

Aim: To investigate the effect of Carica papaya seed extract on KBrO3 - induced nephrotoxicity in rats. Renal toxicity was induced by a single oral dose of 100 mg/kg body weight of KBrO3. Study Design: Thirty (30) male albino rats were divided into six groups, five rats per group...

Open access Research Article 10.9734/ajbgmb/2019/v2i130051

To Evaluate the Association between Serum Leptin and Insulin/Insulin Resistance in Polycystic Ovarian Syndrome in a Tertiary Care Centre in North India

Manohar Athrey, Manjulata Kumawat & Sameer Aggarwal · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

Background: Polycystic ovarian syndrome (PCOS) a common endocrinological disorder among women in the reproductive age group, is associated with hyperinsulinemia/Insulin resistance, obesity, menstrual irregularities and anovulation. Aim and Objectives: The present study was conduc...

Open access Research Article 10.9734/ajbgmb/2019/v2i130050

Influence of Age, Sex and Body Mass Index on the Levels of Glycosylated Haemoglobin among Non-Diabetic Nigerian Population

Ani, Chijioke Collins, Ojobor, Charles Chijioke, Ezeanyika, Lawrence Uchenna Sunday & Obi, Bonaventure Chukwunonso · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

The influence of age and sex on the levels of glycosylated haemoglobin among non-diabetic Nigerian population were investigated in this study. Seventy-nine non-diabetic individuals volunteered for the study and were grouped into male and female and then into four groups according...

Open access Research Article 10.9734/ajbgmb/2019/v2i130049

Total Phenolics, Flavonoids Contents, Antioxidant Activity and DNA Protective Effect of Lenten Rose (Helleborus orientalis)

Meral Öztürk, İbrahim Bulduk, Safiye Elif Korcan, Recep Liman, Funda Karabağ Çoban, Mustafa Kargıoğlu & Muhsin Konuk · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

The aims of the present study were to evaluate the antioxidant activity and DNA Protective effect of Helleborus orientalis (HO) leaf extract against oxidative damage, and to determine the total phenolic and flavonoid contents of the plant species studied. Methods: The total pheno...

Open access Research Article 10.9734/ajbgmb/2018/v1i430047

Phytochemical Screening of Etlingera elatior (Torch Ginger) Cultivated on Different Dosage of Biochar

Isaac John Umaru, Benedict Samling & Hauwa A. Umaru · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

Objective: This study was carried out with an objective to investigate the impact of biochar on phytochemical composition in plant especially Etlingera elatior cultivated on different dosage of biochar. Methods: Etlingera elatior was cultivated on the pot with 20 cm diameter and...

Open access Research Article 10.9734/ajbgmb/2018/v1i430048

Evaluation of the Cardioprotective Effect of Citrullus lanatus (Watermelon) Seeds in Streptozotocin Induced Diabetic Albino Rats

C. O. L. Karikpo, E. S. Bartimaeus & B. Holy · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

The study examined the cardioprotective potential of the ethanolic extract of Citrullus lanatus in streptozotocin induced diabetic albino rats. A total of sixty albino rats weighing approximately ± 200 g were used. The induction of diabetes in the rats was done using 50 mg/kg bod...

Open access Research Article 10.9734/ajbgmb/2018/v1i430046

Improvement of Multiple-Locus VNTR Analysis Typing Scheme for Helicobacter pylori

Vladimir M. Sorokin, Ruslan V. Pisanov & Aleksej S. Vodop'janov · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

Aims: To improve a multiple-locus variable-number tandem-repeat (VNTR) analysis (MLVA) assay for Helicobacter pylori typing. Materials and Methods: Polymorphic VNTRs were searched by Gene Expert. The distribution and polymorphism of each VNTR locus were analyzed in 18 H. pylori g...

Open access Research Article 10.9734/ajbgmb/2018/v1i430045

Mitotic Studies and Genotoxic Assessment of Edible Nigerian Aroids to Selected Oilfield Chemicals

Florence O. Ajah, Julian O. Osuji & Geoffrey O. Anoliefo · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

The genotoxic potentials of two water-based oilfield chemicals on edible aroids were investigated. Five accessions of Colocasia eculenta and three accessions of Xanthosoma maffafa were exposed to graded concentrations of sodium azide and potassium chromate; while the accessions w...

Open access Research Article 10.9734/ajbgmb/2018/v1i429646

Effect of Elapsed Time after Blood Collection on the Viability and Mitotic Index of Human Lymphocytes during Karyotype Analysis

Doaa Hussein El-Khateeb, Ashraf Abd Elraouf Khalil, Ibrahim Tantawy El Sayed & Hala Hany EL-Said · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

Background: Chromosome staining using G banding is a commonly used technique during karyotyping, however, a limited number of laboratories carries out the test. Blood samples must be sent to the laboratory on the same day of sample collection. Aim: To assess the effect of time pa...

Open access Research Article 10.9734/ajbgmb/2018/v1i329640

Measurement of Serum Lipid Profile Parameters, Blood Urea Nitrogen, Serum Uric Acid and Serum Creatinine Levels for Children with Acute Lymphoblastic Leukemia

Sundus Fadhil Hantoosh, Farah T. O. Al Jumaili & Dheaa Shamikh Zageer · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

Introduction: Leukemia is the commonest malignancy of childhood and is the causative of a third of childhood cancer deaths. Lipid abnormalities have been recognized in children with acute lymphoblastic leukemia (All). Kidney involvement in leukemia can be quite immense. Aim: This...

Open access Research Article 10.9734/ajbgmb/2018/v1i329639

Clinical Diagnosis of Disease States Using Enzymes and Proteins (Review)

Ngabonzima Evalde, Prince Ogaranya James, Onyinyechukwu Onuorah, Charity Chinyere Ilo, Donatus Okeowhor, Samuel Cosmas & Olanrewaju Ayodeji Durojaye · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

Disease states which are abnormal conditions that negatively affects the structure or function of parts or all of an organism usually lead to moderate or extensive tissue damage depending on the time of onset and severity of the disease. Such tissue damages are usually associated...

Open access Research Article 10.9734/ajbgmb/2018/v1i329642

Heritability and Correlations for Agronomic and Physiologic Traits of Maize under Deficit Irrigation at Two Growth Stages

A. M. M. Al-Naggar, M. M. Shafik & M. O. A. Elsheikh · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

Strong associations between agronomic and physiologic traits and drought tolerance, high heritability and high genetic advance for such traits would allow plant breeder to use such traits as selection criteria for selecting drought tolerant genotypes. The objectives of the presen...

Open access Research Article 10.9734/ajbgmb/2018/v1i327501

The Impact of EVI1 on Carbonic Anhydrase III Expression and the Sensitivity of Rat1 Fibroblasts to H2O2-induced Apoptosis

Ali Mohammed Abdullah Albishi · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2018

EVI1 is a transcriptional factor with two distinct zinc finger domains and encoded in human chromosome 3q26. In human, the protein is believed to have role in cell proliferation, organogenesis and it was detected in kidneys and lungs. EVI1 overexpression has been associated with...

Open access Research Article 10.9734/ajbgmb/2018/v1i327499