Amylase, a crucial enzyme within biological systems, reveals its catalytic effectiveness in facilitating the breakdown of complex carbohydrates through hydrolysis. This study sought to isolate, partially purify, and investigate the inherent physicochemical properties of amylase d...
Open access
Research Article10.9734/ajbgmb/2025/v17i11501
Crab-associated microbiomes play critical roles in host nutrition, immunity, and ecological adaptation, yet remain poorly characterized for many ecologically and economically important species. Here, we present the first high-throughput 16S rRNA gene sequencing analysis of gut mi...
Open access
Research Article10.9734/ajbgmb/2025/v17i10499
The human microbiome, a complex ecosystem of trillions of microorganisms, is now recognized as a virtual endocrine organ that profoundly influences host physiology. Beyond its role in metabolism and immunity, the microbiome produces a vast repertoire of small molecules that can m...
Open access
Research Article10.9734/ajbgmb/2025/v17i10498
Aims: To design, validate, and partially express a novel large molecule immunotherapeutic candidate targeting MYC and CTNNB1, key oncogenes implicated in hepatocellular carcinoma (HCC), using in silico computational approaches. Study Design: In Silico Studies using Computational...
Open access
Research Article10.9734/ajbgmb/2025/v17i10497
According to the World Health Organisation, over 537 million adults currently live with diabetes. Despite the availability of pharmacological treatments such as insulin and oral hypoglycemic agents, these options often come with significant drawbacks. As a result, there is increa...
Open access
Research Article10.9734/ajbgmb/2025/v17i10496
Aims:.Cervical cancer is predominantly associated with persistent infection from high-risk human papillomavirus (HPV) strains, especially HPV16.This study focuses on the in silico design of a multiepitope- based recombinant vaccine targeting the E6 and E7 oncoproteins of HPV16. T...
Open access
Research Article10.9734/ajbgmb/2025/v17i10495
There are many persistent heavy metals released into our environment, among which are heavy metals. This study was conducted to determine the concentrations of selected heavy metals—cobalt (Co), manganese (Mn), iron (Fe), and silver (Ag)—in fish, water, and sediment samples colle...
Open access
Research Article10.9734/ajbgmb/2025/v17i10494
Aim: To correlate the biological effect of sialic acid on the expression of high mobility genes in the human astrocytoma cell line with regard to its therapeutic potential. Methodology: After the treatment of 1321N1 cells (human astrocytoma cells) with Sialic acid in different do...
Open access
Research Article10.9734/ajbgmb/2025/v17i9493
Introduction: Hypovitaminosis D is a real public health problem. Populations in sub-Saharan Africa, despite favorable sun exposure, are not immune to this scourge. Among the reasons mentioned are the inhibitory action of melanin on the cutaneous synthesis of vitamin D but also th...
Open access
Research Article10.9734/ajbgmb/2025/v17i9492
In Nigeria, shrimps, commonly referred to as crayfish, represent a highly nutritious food source offering substantial amounts of protein, essential fatty acids, vitamins, and minerals, thus contributing significantly to dietary needs. Shrimps and other marine species are crucial...
Open access
Research Article10.9734/ajbgmb/2025/v17i9491
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by persistent inflammation and oxidative stress, with reactive oxygen species (ROS) playing a key role in its pathogenesis. Silver nanoparticles (AgNPs) possess redox-modulating and immunomodulat...
Open access
Research Article10.9734/ajbgmb/2025/v17i9490
Almost half of cases of infertility, which is defined as the inability to conceive after a year of unprotected sexual activity, are caused by male factors. Infertility is still a global health concern. The mitochondria are one of the main biological contributors to energy metabol...
Open access
Research Article10.9734/ajbgmb/2025/v17i9489
Background: Self-monitoring of blood glucose is essential for effective diabetes management, necessitating the use of glucometers that maintain precision and accuracy. Environmental factors and prolonged usage may impact their performance. However, there is limited knowledge rega...
Open access
Research Article10.9734/ajbgmb/2025/v17i9487
Pathogenic microorganisms are constantly developing resistance, hence the need for medicinal plant remedies; Allium cepa (Onion),Allium sativum (Garlic) and Zingiber officinale (Ginger) have been playing a vital role on the health and healing of man since human civilization. The...
Open access
Research Article10.9734/ajbgmb/2025/v17i9486
The present study investigated the comparative effects of varying intensities of alternating magnetic field and Tithionia diversifolia crude extract on hematological parameters of mice infected with Plasmodium berghei. Experimental solenoids were designed to generate the magnetic...
Open access
Research Article10.9734/ajbgmb/2025/v17i8485