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All published articles 550

Analgesic Activity of Alchornea laxiflora Stembark Extract in Mice

Jude E. Okokon, Anwangabasi E. Udoh, Chinyelu Clementina Osigwe, Ugonma Florence Uwaeme & Henry Thomas Okon · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Alchornea laxiflora is used in Ibibio ethnomedicine for the treatment of various diseases such as pains. This work was designed to validate and confirm the ethnomedical use of this plant in the treatment of pain.  The ethanol stembark extract of Alchornea laxiflora (141-424 mg/kg...

Open access Research Article 10.9734/ajbgmb/2025/v17i6470

A Cross-Sectional Study of Heavy Metal Presence and the Health Implications among Automobile Repairers at Benin City Metropolis, Nigeria

Raymond Iduojemu Ozolua, Nzube Gabriella Chukwujindu, Ebuka Oritsela Obobo, Elohor Okpakpor, Sunday Maliki Momoh, Osaretin Godwin Igharo & Ekene Victor Asoya · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Background: Heavy metal exposure may manifest as neurological, dermal, immunological, cardiovascular, renal, hepatic, hematological, respiratory effects, and cancers. Automobile repairers are workers who are engaged in adjusting, repairing, and overhauling automobiles. Entry of h...

Open access Research Article 10.9734/ajbgmb/2025/v17i6468

Assessment of Minerals, Phytochemicals, Proximate and Vitamins Content of Musa acuminata Treated with Different Ripening Agents

Chigoziri Akudo Osuji · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

The use of artificial ripening agents in fruit handling has raised growing concerns due to potential health implications and nutrient degradation. Since musa acuminata (banana) is a climacteric fruit, it is usually harvested at pre-climacteric stage and for commercial purposes, a...

Open access Research Article 10.9734/ajbgmb/2025/v17i5467

Evaluation of the Renal Function in Anti-obesity Effects of Ethanolic Extract of Citrus sinensis Peel Treated Wistar Rats

Chigoziri Akudo Osuji & Ofoegbu, Destiny Chigemezu · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Obesity is a global health concern linked to oxidative stress and kidney dysfunction. Citrus sinensis (sweet orange) peels, typically a waste product, are rich in bioactive compounds with antioxidant potential. This study evaluated the protective and antioxidant effects of sweet...

Open access Research Article 10.9734/ajbgmb/2025/v17i5466

Exploring the Antidiabetic Potential of Azanza garckeana Parts on Streptozotocin Induced Diabetic Rats

Comfort Philip Japhet, Carrol Domkat. Luka & Ishaya Yohanna. Longdet · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Diabetes mellitus is a chronic, incurable metabolic disorder caused by the lack of secretion of insulin by the pancreas. Currently, several plants are used for the treatment of diabetes mellitus. Azanza garckeana, a plant with notable medicinal properties, has been characterized...

Open access Research Article 10.9734/ajbgmb/2025/v17i5465

Evaluation of the Antifungal Activity of Azadirachta indica Leaf Extracts and Fractions against Clinically Resistant Fungal Isolates

Chidimma R. Chukwunwejim, Ekene O. Onyeogulu, Miriam Goodness U. Nwaneri, Ijeoma N. Ebenebe & Chinenye H. Nedum · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

The emergence of fungal resistance to antifungal agents is a significant concern, it leads to treatment failure and poor clinical outcomes. Fungal infections pose significant concern to human health, agriculture and the environment. Hence the need for alternative antifungal agent...

Open access Research Article 10.9734/ajbgmb/2025/v17i5464

Oxidative Stress and Its Role in the Toxicity of Smoked Fish Extract in Albino Rats

Opusunju Boma Harris, Wokocha Peter Gift & Opusunju Mandu Boma · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

This study aimed to investigate the role of oxidative stress in the toxicity induced by smoked fish extract in albino rats, with a particular focus on the biochemical markers of oxidative damage. A total of 20 male albino rats, weighing 180–220 g, were divided into four groups: a...

Open access Research Article 10.9734/ajbgmb/2025/v17i5463

Histopathological Evaluation of Liver and Kidney Damage Induced by Smoked Fish Extract

Opusunju Boma Harris, Wokocha Peter Gift & Opusunju Mandu Boma · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

This study aimed to evaluate the histopathological effects of smoked fish extract on liver and kidney tissues in albino rats, focusing on the structural damage induced by prolonged exposure to smoked fish contaminants. A total of 20 male albino rats (mean weight: 200 ± 12.5 g) we...

Open access Research Article 10.9734/ajbgmb/2025/v17i5462

Evaluation of Genotoxic and Cytotoxic Activities of Cornsilk, (Stigma maydis) Extract of Zea mays L.

Chinyelu Clementina Osigwe, Jude E. Okokon, Ugonma Florence Uwaeme, Ezinne Mmekam & Imoh Imeh Johnny · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Allium cepa test was employed to evaluate genotoxic and cytotoxic potentials of cornsilk of Zea mays L. (Poacae), which is traditionally used as a remedy to various ailments. Macroscopic and microscopic analyses were carried out on Allium cepa root meristem cells exposed to corns...

Open access Research Article 10.9734/ajbgmb/2025/v17i4461

The Intimate Read: Nanopore Sequencing and the Philosophical Recalibration of Life's Code

Héctor Guzmán García · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Nanopore sequencing represents a paradigm shift in how we read and interpret the genetic and epigenetic information of living organisms. Unlike traditional sequencing methods that rely on amplification and fragmentation, nanopore sequencing enables the direct, real-time analysis...

Open access Research Article 10.9734/ajbgmb/2025/v17i4459

Glucose-Induced Production of Secondary Metabolites by Lasiodiplodia theobromae

U.M. Okezie, C.I. Chimezie, N.J. Okonkwo-Uzor, V.U. Chigozie, O.G. Tochukwu, I.N. Okpoli, M.G.U. Nwaneri, J. E. Achilonu, O.B. Ifeagwu, C.J. Ikem, C.C. Onwuzuligbo & S.H. Buzugbe · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Microbial chemodiversity of bioactive secondary metabolites remains largely unexplored for use as new antimicrobial agents. Current advances employed to exploit this plethora of bioactive compounds from microbes are focused on the stimulation of physiological processes that induc...

Open access Research Article 10.9734/ajbgmb/2025/v17i4458

Antiulcer Activity of Justicia insularis Leaf Extract on Experimentally-Induced Ulcers in Rats

Ugonma Florence Uwaeme, Chinyelu Clementina Osigwe & Jude Efiom Okokon · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Peptic ulcer disease (PUD) is a significant gastrointestinal disorder that affects millions of people worldwide, imposing substantial burden on individuals, healthcare systems and economies. The available treatment options are not devoid of attendant sequalae. The search for less...

Open access Research Article 10.9734/ajbgmb/2025/v17i4457

Mitracarpus scaber and Ageratum conyzoides in the Traditional Management of Eczema in Nigeria: A Review

Emmanuel O. Eromosele, Nkeonyeasua J. Ehiwario, Madu Peace Chioma & Oseghale Emmanuel Ehilen · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

This review aims to examine the use of Mitracarpus scaber and Ageratum conyzoides in the traditional management of eczema in Nigeria, with an emphasis on their bioactive compounds. Various medicinal plants are used globally in the treatment of different skin diseases such as ecze...

Open access Research Article 10.9734/ajbgmb/2025/v17i4456

Bioactive Analysis of Anthocleista vogelii Leaves for Therapeutic Potential in Haemolytic Anaemia

Nzor, Joyce Nornubari & Okoroh, Prince N · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Aims: The study aimed to evaluate the proximate and mineral composition and identify bioactive compounds in the methanol leaf extract of Anthocleista vogelii using gas chromatography-mass spectrophotometer (GC-MS analysis), with a focus on its potential antioxidant, antimicrobial...

Open access Research Article 10.9734/ajbgmb/2025/v17i4455