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All published articles 550

Genotoxic and Cytotoxic Activities of Leaf Extract of Stachytarpheta cayenensis (Rich). Vahl

Chinyelu Clementina Osigwe, Jude E. Okokon, Ugonma Florence Uwaeme & Imoh Imeh Johnny · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

The many pharmacological potentials of Stachytarpheta cayennensis (L.C. Rich) Vahl, (Verbenaceae), commonly called blue snakeweed and its use in traditional medicine in Nigeria such as in the treatment of hypertension, diabetes, mental illness and infections, could position it as...

Open access Research Article 10.9734/ajbgmb/2025/v17i4454

Impact of Tiger Nuts and Date Palm flour Mixture on Reproductive Functions of Male Wistar Albino Rats

Ogechi Norah Alfred-Victor, Eka Bassey Essien, Kingsley Chukwuemeka Patrick-Iwuanyanwu & Kelechi ThankGod Nwauche · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

The use of synthetic drugs in the treatment of infertility is quite expensive and has shown to produce some adverse effects. Natural remedy such as the use of plants is recommended because they pose little or no side effects. This present work is on Impact of Tiger nuts and Date...

Open access Research Article 10.9734/ajbgmb/2025/v17i4453

Differential Gene Expression Analysis and Biomarker Identification for Colorectal Cancer

Madhumitha G & Pujaa B · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Background: Colorectal cancer is a multifaceted disease with complex molecular mechanisms influencing its onset and progression. CRC has been observed to exhibit familial clustering patterns since the early 1900s. Like the majority of cancers, colorectal cancer can develop as a r...

Open access Research Article 10.9734/ajbgmb/2025/v17i4452

The Protective Effect of Atorvastatin Against Indomethacin-induced Gastric Ulceration in Rats

Imaobong Christopher Etti, Victor Neeka Maximum & Uduak Anthony Inwang · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Background: Gastric ulcer, a disruption of the normal gastric mucosal integrity, poses a significant clinical challenge, necessitating the exploration of novel therapeutic strategies. Aim: This study investigated the potential gastroprotective effects of atorvastatin, a statin wi...

Open access Research Article 10.9734/ajbgmb/2025/v17i3451

Ferulic Acid as a Potential Drug for Neurological Disorder: An In silico Approach

Suyash Sawale, Robin Mathew, Merwyn D’Costa, Nikhil Gadewal, Arvind Singh & Shashibhal Pandey · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Glycogen synthase kinase-3 (GSK-3) has been known to regulate various cellular and metabolic processes, including neuronal plasticity. Dysregulation of the GSK-3β isoform leads to the development of various neurological disorders such as Alzheimer’s, Parkinson’s, and Huntington’s...

Open access Research Article 10.9734/ajbgmb/2025/v17i3450

Early Detection and Management of Glucose-6-Phosphate Dehydrogenase Deficiency through Newborn Screening: A Case Study and Public Health Perspective

Rahul Gopalakrishnan, Vijayakumar PG, Seethalakshmi S & Lydia Jeris W · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Newborn screening is a crucial public health program aimed at early detection of genetic, metabolic and endocrine disorders in infants, enabling prompt intervention to prevent long-term complications and improve outcomes. This study focuses on the importance of screening for cond...

Open access Research Article 10.9734/ajbgmb/2025/v17i3448

Influence of Alcohol Intake on Heavy Metal Accumulation in Artisans from Three Locations in Port Harcourt, Rivers State, Nigeria

Adele, U.A., Brown, H., Onwuli D.O. & Bartimaeus, E.S. · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Aim: The present study assesses the levels of some heavy metals in artisans in Rivers State, Nigeria Study Design: This is a Cross-sectional study. Place and Duration of Study: Automobile workshops, welding workshops, and painting workshops, located in Mile 3 mechanic garage, Ele...

Open access Research Article 10.9734/ajbgmb/2025/v17i3449

Assessing the Antidiabetic Properties of Methanolic extract of Baccaurea motleyana leaf in Alloxan-induced Diabetic Mice

Md. Atiq Ashhab, Md. Monirul Islam, Md. Muhaimanul Haque, Md. Sohan Ahmed, Md. Mehebub Al Raji, Mokhleshur Rohman, Zakia Sultana Juthi & Mohammad Amirul Islam · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Background: Medicines made from Baccaurea motleyana are used to treat a wide range of illnesses. The current study targeted to investigate the methanolic extract of Baccaurea motleyana leaf's antidiabetic qualities. Results: The leaf extract of Baccaurea motleyana at a concentrat...

Open access Research Article 10.9734/ajbgmb/2025/v17i3447

Nutritional and Health Effects of Grasshopper-Enriched Sprouted Soybean/Millet-Based Complementary Food: A Study on Gut Health Markers in Rats

Sambo Ponfa, Gyenvwot Pyokpang Adamu, Naanswan Joseph Dasoem, Lombin Zhianbyen Emmanuella, Wazhi Ponnak Ezekiel & Aisha Gadanya Muhammad · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

This study aimed to develop and assess the effects of sprouted soybean/millet-based complementary food on gut health markers in rats. Four diets were formulated: sprouted millet (CFB), sprouted soybean (CFC), sprouted soybean/millet (CFD), and grasshopper-enriched sprouted soybea...

Open access Research Article 10.9734/ajbgmb/2025/v17i3446

Effects of Persea americana Seed Extract on Lipid Profile, Atherogenic and Coronary Risk Indices in Doxorubicin-injected Male Rats

Ejiogu Ikedichukwu Chibueze, Maduka Hugh Clifford Chima & Maduka Ignatius Chukwudi · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Doxorubicin (DOX) can cause disruption in the lipid profile due to free radical process. The health benefits of avocado seeds stem from essential nutrients and phytochemicals. This study aimed to assess the effects of Persea americana seed extract on lipid profile, atherogenic an...

Open access Research Article 10.9734/ajbgmb/2025/v17i3445

Molecular Detection of blaNDM-1 Gene of Escherichia coli isolates from Different Clinical Samples in Khartoum State

Husham M Taha Aloob, Amal Alfatih Babeker Alhag, Abdelhakam H Ali, Samia S Mohamed Ismail, Amira H Arman, Ahmed AbdElhadi Abdlhamed Ibrahem, Wahaj.M.M & Waleed Abdelateif Hussein · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Background: Increasing reports on NDM-1 producing E. coli constitute a serious threat to global health since it is found to be highly resistant to most of the currently available antibiotics, including carbapenems family like Meropenem and Imipenem. Objective: This study aim to d...

Open access Research Article 10.9734/ajbgmb/2025/v17i3444

Sickle Cell Disease in Sub-Saharan Africa: Is CRISPR-Cas9 the Breakthrough We’ve Been Waiting for?

Christopher Aloy Simeon, Godae Fidelis Beega, Covenant Oluwadamilola Adeshina, Elizabeth Funmi Bassey, Prudence Nkechinyere Nkpurukwe & Ekprikpo Erens Spiff · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Sickle cell disease, which results from a single nucleotide substitution in the beta-globin gene (HBB) is recognized as a significant global health concern. Approximately 7.74 million people worldwide were living with sickle cell disease in 2021. Sub-Saharan Africa carries the hi...

Open access Research Article 10.9734/ajbgmb/2025/v17i2443

Nutritional Potential and the Effect of Ethanol and Aqueous Extracts of Plukenetia conophora Leaf on the Body Weight and Blood Glucose Concentrations of Diabetic Rats

Prince, N. Okoroh, Daniel Orieke, Kelechi Light Ekeke, Chigoziri, A. Osuji & Adjeyakpo Ejiroghene Benedeth · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Proximate composition and energy value, macro-mineral concentration, percentage daily value (%DV), nutrient rich index (NRI) and the effect of ethanol and aqueous extracts of Plukenetia conophora leaves on the body weight and blood glucose concentration of diabetic rats were dete...

Open access Research Article 10.9734/ajbgmb/2025/v17i2442

Management Practices at Poultry Demonstration Centres for Boosting Backyard Poultry Farming System in Ramban District of Jammu & Kashmir, India: A Review

Wani Ahad · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

The Backyard poultry farming is an age-old practice in India and plays an important role to reduce poverty among the most under-privileged sections of the Jammu & Kashmir, particularly in far flung areas of rural J&K, India. There is not any specific arrangement required...

Open access Research Article 10.9734/ajbgmb/2025/v17i2441

Effect of Vitamin A on Glucose Tolerance in Female Undergraduates of Ambrose Alli University, Ekpoma

Sophia I Edobor, Abraham O. Onigbinde & Fiderikumo Livingstone Gbeinbo · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Background: This study explored the effects of Vitamin A supplementation on glucose tolerance among female undergraduate students at Ambrose Alli University, Ekpoma, adopting a comprehensive metabolic approach. Recent evidence has established that retinoid signaling pathways inte...

Open access Research Article 10.9734/ajbgmb/2025/v17i2439