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All published articles 517

In-vitro Biochemical Studies on Organometallic Compounds as Anticancer Agents

F. Z. Mohammed, Elsherbiny H. Elsayed, Atef E. Abd Elbaky & H. M. Shalaby · Asian Journal of Research in Biochemistry · 2019

This study aims to synthesis of copper complexes of 2,3-dihydroxy benzaldehyde thiosemicarbazone (3a,b), followed by evaluating their in vitro anticancer properties. The prepared compounds have been also evaluated for their ability to induce apoptosis. A total number of 80 adult...

Open access Research Article 10.9734/ajrb/2019/v5i130080

Examination of Conditions for Optimized Decellularized Liver Preparation

Jaeyong Cho, Yukako Fukuda, Nana Shirakigawa & Hiroyuki Ijima · Asian Journal of Research in Biochemistry · 2019

Aims: The main aim of our study was to examine the concentration of surfactant that can cause significant disruption of the resulting decellularized liver structure. Furthermore, it is our goal to determine the suitable solvent that can boost the potential of each surfactant. Met...

Open access Research Article 10.9734/ajrb/2019/v5i130079

Qualitative and Quantitative Phytochemical Screening, Antioxidant and Anti-inflammatory Activities of Acetone Extract of Brassica juncea L. Leaf

Pratima Khandayataray & Meesala Krishna Murthy · Asian Journal of Research in Biochemistry · 2019

Objective: The aim of this study is to evaluate the phytochemical screening; antioxidant and antiinflammatory activity of acetone extract of Brassica juncea (L.) Czern leaf. Methods: Qualitative and quantitative phytochemical screening was conducted by following standard protocol...

Open access Research Article 10.9734/ajrb/2019/v5i130078

Toxicity Impact on Bioaccumulation of Potentially Toxic Elements in African Giant Land Snail (Archachatina margenata) Treated with Different Soils and Its Ecological Risk Assessment

Oguh C. Egwu, Ugwu C. Victor, Uzoefuna C. Casmir, Usman Sa’adat, Nkwocha C. Chibueze & Amanabo Musa · Asian Journal of Research in Biochemistry · 2019

This study investigated the concentrations of heavy metals (As, Cd, Cr, Cu, Hg and Pb) in African Giant Land Snail (AGLS) treated with different soil samples dumpsite (A), mining site (B) and control soil (C) (a reserve area where no activities) use in farming AGLS and also to as...

Open access Research Article 10.9734/ajrb/2019/v4i430077

Combined Antioxidant Recovery Properties of Fruit Juice Extracts of Cucumber and Water Melon on Lipid Profile and Gonadal Steroid Levels of Cadmium Induced Testicular Damage on Male Albino Rats

F. C. Anacletus, B. Nwakaku & K. T. Nwauche · Asian Journal of Research in Biochemistry · 2019

The antioxidant protective effects of fruit juice of cucumber and watermelon on lipid profile of cadmium induced toxicity on male albino rats was investigated. Forty male rats were divided into eight groups. Group NC served as normal control group while group PC was positive cont...

Open access Research Article 10.9734/ajrb/2019/v4i430076

Antifungal Action of Garlic (Allium sativum) and Ginger (Zingiber officinale) on Some Pathogenic Fungi

V. N. Agi & C. A. Azike · Asian Journal of Research in Biochemistry · 2019

Background: The antifungal activities of fresh garlic (Allium sativum) and ginger (Zingiber officinale) on the growth of three known pathogenic fungi were investigated. The test organisms were Aspergillus spp Penicillium spp and Candida albicans. Methodology: Two different concen...

Open access Research Article 10.9734/ajrb/2019/v4i430075

Biochemical Indices and Haematological Studies of Ethyl Acetate Extract of Persea americana Leaf in Albino Rats

J. A. Mashi, A. M. Sa’id, F. Bello, H. M. Yakasai, B. Bello & R. I. Idris · Asian Journal of Research in Biochemistry · 2019

The aim of this present study was to evaluate the effect of ethyl acetate extract of P. americana (avocado) on liver and kidney function, lipid profile as well as haematological parameters in albino rats. A total of 20 albino rats were used for this experiment and they were divid...

Open access Research Article 10.9734/ajrb/2019/v4i430074

Biochemical Parameters, Activity Levels of Marker Enzymes and Serum Electolytes of Wistar Albino Rats Fed Mango (Mangifera indica) Pulp Formulated Diets

Pauline N. Iheagwam, Eugene N. Onyeike & Benjamin A. Amadi · Asian Journal of Research in Biochemistry · 2019

Biochemical parameters, activity levels of marker enzymes and serum electrolytes of Wistar albino rats fed naturally ripe (control), unripe and artificially ripened mango pulp formulated diets were investigated. Ripe and unripe fruits were collected and used for the study and art...

Open access Research Article 10.9734/ajrb/2019/v4i330072

Effect of Oral Intake of African Locust Bean on Fasting Blood Sugar and Lipid Profile of Albino Rats

Augustine I. Airaodion, Edith O. Airaodion, Emmanuel O. Ogbuagu, Uloaku Ogbuagu & Etinosa U. Osemwowa · Asian Journal of Research in Biochemistry · 2019

Background: African locust bean is a condiment believed to be for the people of low class. Its health importance has not been fully known especially to the so-called high class. Aim: This study is aimed at investigating the effect of African locust bean on fasting blood sugar and...

Open access Research Article 10.9734/ajrb/2019/v4i430073

Effects of ‘ZPC’ Polyherbal Formulation on Diabetic-Dyslipidemic Wistar Rats

Agatemor Uzuazokaro Mark- Maria, Ozioko Eucharia Ngozi, Momoh Theophilus Boniface, Idakwoji Precious Adejoh & Nweje- Anyalowu Paul Chukwuemeka · Asian Journal of Research in Biochemistry · 2019

In this study the antidiabetic effect of a polyherbal formulation- ZPC was investigated in Wistar rats. Diabetes was induced by intraperitoneal injection of streptozotocin at a dose of 50 mg/kg. Rats having Fasting Blood Sugar (FBS) level above 250 mg/dl after 72 hrs were conside...

Open access Research Article 10.9734/ajrb/2019/v4i330071

Synthesis, Characterization and Cytotoxic Activity of N-(5-indanyl(methylene)anthranilic acid(5-indanyl methylene)-hydrazide and Its Pt(II) Complex

Nasser Mohammed Hosny & Lamiaa A. A. Barakat · Asian Journal of Research in Biochemistry · 2019

Since the discovery of the platinum based complex, cisplatin, medicinal inorganic chemistry has attracted much more attention and a large number of platinum complexes with promising pharmacological properties have been synthesized. In this work a new platinum complex of N-(5-inda...

Open access Research Article 10.9734/ajrb/2019/v4i330070

Biochemical Studies on Coumarin Derivatives as Antioxidant and Antitumor Agents

F. Z. Mohammed, I. M. El-Deen & A. S. Tmamm · Asian Journal of Research in Biochemistry · 2019

Background: Coumarin derivatives have attracted intense interest in recent years, because they have anti-tumor, antioxidant activities, and induce apoptosis. Aims and Objective: Our study aims to evaluate the antitumor and anti-oxidant activities of new Coumarin derivatives: N-(P...

Open access Research Article 10.9734/ajrb/2019/v4i330069

Activity Coefficient of Solution Components and Salts as Special Osmolyte from Kirkwood-Buff Theoretical Perspective

Ikechukwu Iloh Udema & Abraham Olalere Onigbindec · Asian Journal of Research in Biochemistry · 2019

Background: There has been different interpretation of kosmotropes and chaotropes without concern for the physicochemical characteristics of the macromolecule and for the link between Hofmeister phenomena with solution structure. The objectives of this research are: 1) To investi...

Open access Research Article 10.9734/ajrb/2019/v4i330068

Biochemical Study of Gender Effect on Thyroid Cancer in the Egyptian Population

Faten Zahran, Sahar Hamed, Mohamed Yosry & Mohamed El Gareeb · Asian Journal of Research in Biochemistry · 2019

Background and Objective: Thyroid is one of the largest glands; its hormones affect almost every cell in the body, the incidence of thyroid cancer has raised in recent years, About 52,070 new cases of thyroid cancer in the United States in 2018 only. This study was undertaken to...

Open access Research Article 10.9734/ajrb/2019/v4i230066

Assessment of Bread in Ogbomoso Metropolis for the Presence of Potassium Bromate

Augustine I. Airaodion, Olaide O. Awosanya, Emmanuel O. Ogbuagu, Uloaku Ogbuagu, Onyinyechi C. Njoku, Chimdi Esonu & Edith O. Airaodion · Asian Journal of Research in Biochemistry · 2019

Aim: This study is aimed at evaluating the level of potassium bromate in bread in Ogbomoso metropolis. Study Design: This study was made to fit a one way Analysis of Variance (ANOVA). Place and duration of Study: The bread samples were purchased in Ogbomoso metropolis and analyze...

Open access Research Article 10.9734/ajrb/2019/v4i230065