Mitsan Olley, Sule Zekeri, Josiah Joel Sunday, Aiyanyor David Osayomwanbo & Awa Favour Chinatu·Asian Hematology Research Journal·2023
Blood transfusion is a critical part of patient’s intensive care and is life saving for patients with severe anemia or hemorrhage. The goal of blood banking is to provide adequate and safe blood to recipients at no risk to donors. These donors may have had a variety of exposures...
Salman Taha Ahmed Elmukashfi, Walaa Maryoud Aljack, Mihad Magboul Ahmed, Abdelrahman Mohamed Sidahmed Mohamed & Ahmed Yasin Hassan·Asian Hematology Research Journal·2023
Background: A wide array of disturbances in electrolyte equilibrium is commonly seen in patients with acute leukemia (AL). These abnormalities present a potential hazard in these patients, as that of enhancing the cardio-toxic effects of certain chemotherapeutic regimens. Materia...
Introduction: SARS-CoV-2 infection can cause manifestations in multiple systems in the body. Haematological system can also be affected by both SARS-CoV-2 infection and critical illness. There have been studies that show thrombocytopaenia is connected with SARS-CoV-2 infection. ...
Abhay A. Bhave, Sarang Waghmare, Nitin Chavan, Kashvi Mehta, Fatema Rangwalla & Shrinath Kshirsagar·Asian Hematology Research Journal·2023
Introduction: Hemophagocytic lymphohistiocytosis (HLH) is a fatal disorder, characterized by a cytokine storm due to cytotoxic T cell activation, the causes of which are various. Its detection is first on clinical awareness and proved by several tests. However, there is not one s...
Background: Folic acid metabolism has a major role in DNA methylation and synthesis. Genetic Polymorphisms in folate may disrupt enzyme activities and maybe affect the malignant risk. Methionine synthase reductase <MTRR> are very important enzyme for the folate cycle. Objec...
Jatau Ezra Danjuma, Ayuba Zakari, Dahal Abednego Samuel, Okeke Chinedu Nnawike, Adeyemi Ayobola Olusegun, Boli Elias Wada, Bangalu Dauda Yohanna, Ma’an Victoria Tapsuk, Damulak Obadiah Dapus & Egesie Ochaka Julie·Asian Hematology Research Journal·2022
Visceral leishmaniasis is an uncommon parasitic disease in our environment. It can present with features of bone marrow failure characterized by anaemia, leucopenia, and thrombocytopenia which can be fatal if untreated. We present the case of a 23-year-old male, a foreign undergr...
Shaik Rifath, Navatha Vangala, Shantveer G. Uppin, Tara Roshni Paul, S. P. Rajashekar & K. K. Radhika·Asian Hematology Research Journal·2022
Introduction: Sclerosing extramedullary hematopoietic tumor (SEMHT) is an uncommon lesion seen in association with chronic myeloproliferative disorders especially idiopathic myelofibrosis. We present a case of SEMHT in an elderly female, presenting with ascites. Case presentation...
Anaemia encountered frequently with Type-2 Diabetes Mellitus (T2DM) leads to development of micro and macro-vascular complications. Although many studies describe prevalence of anemia among diabetics in other countries no studies are available for Sri Lanka. The aim was to determ...
Chukwurah, Ejike Felix, Ahanonu, Linda Chiemezie, Chukwurah, Felix Chinedum, Onyekachi, Ewa Ibe & Ogbuabor, Alphonsus Ogbonna·Asian Hematology Research Journal·2022
Background: Human immunodeficiency virus (HIV) infection is one of the world’s public health challenges that affect the immune system as well as the haemostatic functions. Aim: This study assessed the platelet count, plateletcrit (PCT), platelet distribution width (PDW) and mean...
Background: The objective of this study was to determinate cytogenetic profiles of patients received at the medical biology laboratory of the Pasteur Institute of Dakar over a 2-year period. Methods: Twenty-nine samples on heparinized tube from patients suspected of having myelop...
Background: Diabetes mellitus has over the years become a public health challenge and a complex disease which is characterized by chronic hyperglycemia that results in microvascular and macrovascular complications. Aim: The present study was designed to determine the hematologica...
Background: High malaria burden has led to the increase use of insecticides in the tropics and subtropics. This study thus aimed at assessing the effect of insecticides inhalation on coagulation profile using experimental animal model. Methods: Sixteen adult male rabbits divide...
Introduction and Aims: Flow cytometry (FCM) has been useful in differentiating abnormal plasma cells (APCs) from normal plasma cells (NPCs) based on the different surface antigen expressions as well as the clonality analysis. The enumeration of NPCs and APCs is of prognostic sign...
Alpha thalassemia (α-thal), fetal haemoglobin (HbF) and beta-globin haplotype are considered classical genetic disease modifiers in Sickle cell disease (SCD) causing clinical heterogeneity. Nevertheless their impact on clinical emergence and disease progression is still elusive....
Transcobalamin II (TC) deficiency is a rare but serious metabolic disorder. It usually presents in the first year of life with failure to thrive, megaloblastic anemia and pancytopenia. Other features includes hypotonia, ataxia, lethargy, vomiting, diarrhea, mucosal ulceration, re...