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All published articles 285

Immunophenotypic Characterisation of Blast Crisis in Chronic Myeloid Leukemia : Experience at a Tertiary Care Centre

Monika Gupta, Shivani Singhal & Sunita Singh · Asian Hematology Research Journal · 2021

Aims and Objectives: Chronic myeloid leukemia (CML) is a clonal stem cell disorder that is hallmarked by the presence of a t(9;22), also known as the Philadelphia chromosome. The natural history of CML is typically triphasic: an initial indolent chronic phase, followed by an acce...

Open access Research Article

Behavioural and Haematological Changes in Pseudomonas aeruginosa Infected Clarias gariepinus Exposed to Carica papaya Root Extracts

O. K. I. Ukwe, I. S. Abbey & O. A. Akinrotimi · Asian Hematology Research Journal · 2021

Behavioural and haematological changes were observed in Pseudomonas aeruginosa infected clarias gariepinus before and after exposure to carica papaya root extracts via immersion. One hundred and twenty (120) c.garipienus of mean weight 120g ± 13g were intramuscularly injected wit...

Open access Research Article

Hepatitis B Virus Awareness and Vaccine Coverage among Voluntary Blood Donors in Jos: Implication for Eradicating the Hepatitis B Virus

Ayuba Zakari, Ezra Danjuma Jatau, Victoria Ma’an Tapsuk, Michael A. Onoja, Dahal Abdenego Samuel & Lami Bako · Asian Hematology Research Journal · 2021

Hepatitis B virus (HBV) is one of the leading causes of chronic viral infections worldwide. The World Health Organization (WHO) aims to eliminate HBV as a global health threat by 2030. Our study, therefore, aimed to identify factors that may hinder the WHO’s objective of eradicat...

Open access Research Article

Uncommon Presentation of Hodgkin’s Lymphoma: A Case Report

C. E. Nonyelu, A. J. Madu, I. O. Anigbogu & O. C. Okafor · Asian Hematology Research Journal · 2021

Hodgkin’s lymphoma is a lymphoid malignancy that rarely presents with extranodal involvement and even rarer is presentation involving the central nervous system (CNS). The index patient had a diagnosis of Hodgkin’s lymphoma made from histology and immunophenotyping of the cervica...

Open access Research Article

Management of Severe Aplastic Anaemia in a Jehovah’s Witness patient: The challenge and Lessons

Nelson I. Oguanobi, Augustine N. Duru, Paul C. Okorie & Amobi O. Egwuonwu · Asian Hematology Research Journal · 2021

Aplastic anaemia is a life threatening consequence of severe bone marrow failure often requiring supportive care with component blood transfusions and stem cell replacement procedures. In this case report and review of literature, the authors highlight peculiar challenges in the...

Open access Research Article

Multiple Myeloma: An In-depth Review of the Historical and Pathogenetic Processes

Anazoeze Jude Madu, Charles Nonyelu, Helen Chioma Okoye & Sunday Ocheni · Asian Hematology Research Journal · 2021

Myeloma is a plasma cell disorder which occurs with varying prevalence across different populations across the globe. Knowledge of the disease pathogenesis as well as its diagnosis and treatment has evolved over the years. The mutations that underlying the progression from benign...

Open access Research Article

Role of Taurine in Children with Anaemia

Arif A. Faruqui · Asian Hematology Research Journal · 2021

Iron deficiency (ID) is the most common health problem noted in paediatric population. The prevalence of anaemia in India among paediatric group is 23.5% in 5-7 years and 58.7% in children below 5 years. The major cause of ID in children is low intake of iron from the actual requ...

Open access Research Article

Validation of Manufacturers Recommended Working Volumes of Fluorochrome-conjugated Monoclonal Antibodies for Flowcytometric Analysis of Lymphocytes

Moses Dabah Lugos, Gwom Irimiya Davou, Tabitha Silas Vem, Venkateswarlu Perikala & Obadiah Dapus Damulak · Asian Hematology Research Journal · 2021

Background: Flow cytometry is a robust and rapidly growing technique used to analyse multiple parameters concurrently on a single cell basis. Cell populations can be characterised using a combination of both surface and intracellular antigens. The act of generating the best resea...

Open access Research Article

Profile of Autoimmune Haemolytic Anaemia: Analysis of 10 Years Data from a Hematology Center in Eastern India

Avriti Baveja, Prakas Kumar Mandal, Arnab Chattopadhyay, Malini Garg, Prakash Singh Shekhawat & Tuphan Kanti Dolai · Asian Hematology Research Journal · 2021

Aims: To study the Clinico-haematological profile and therapy outcome of patients with autoimmune haemolytic anaemia (AIHA) Study Design: Retrospective analysis through the case records of 69 patient treated at the Department of Hematology, NRS Medical College, Kolkata over a per...

Open access Research Article

Acute Promyelocytic Leukemia: A Decade Long Experience with Evolving Treatment Strategies

Prakash Singh Shekhawat, Prakas Kumar Mandal, Malini Garg, Avriti Baveja & Tuphan Kanti Dolai · Asian Hematology Research Journal · 2021

Aims: To study the characteristics and outcome of Acute promyelocytic leukemia (APL) patients. Study Design: Retrospective analysis of APL patients (n=106) treated at the Department of Hematology, NRS Medical College, Kolkata over a period of more than 10 years from October 2009...

Open access Research Article

Manual Exchange Blood Transfusion with Cytoreduction in the Management of Chronic Myelocytic Leukemia with Hyperleukocytosis: A Case Report

Ayuba Zakari, Ezra Danjuma Jatau, Adeyemi Ayobola Olusegun, Akor Akoyi Emmanuel & Dauda Yohanna Bangalu · Asian Hematology Research Journal · 2021

Chronic Myelocytic Leukaemia (CML) is a haematological malignancy characterized by granulocytic leukocytosis, splenomegaly, and weight loss. Hyperleukocytosis can lead to leukostasis and hyperviscosity syndrome. Leukapheresis is used to manage hyperleukocytosis, but apheresis mac...

Open access Research Article