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All published articles 480

Gender-based Experiences of People Living with HIV in Owerri North Local Government Area of Imo State, Nigeria

J. C. Achoronye, M. C. Ezeama, P. O. Chinedu-Eleonu, C. N. Nwadike & U. E. Agubuo · Asian Journal of Medical Principles and Clinical Practice · 2026

Nigeria continues to carry a substantial HIV burden, yet gender-related differences in the lived experiences of people living with HIV remain insufficiently examined at local levels. This study assessed gender-based experiences among adults living with HIV in Owerri North Local G...

Open access Research Article 10.9734/ajmpcp/2026/v9i2467

Effect of Sociodemographic Factors on Uptake of Intermittent Preventive Treatment for Malaria at Antenatal Clinics at Primary Health Centers in Orlu Zone, Nigeria

V. I. Ogoke, K. O. Obasi, I. F. Eberendu, P. O. Chinedu-Eleonu, D. Onyemekara, U. E. Agubuo & C. N. Nwadike · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Intermittent preventive treatment in pregnancy with sulphadoxine-pyrimethamine (IPTp-SP) reduces malaria-related risks, but completion of the recommended dosing schedule remains suboptimal. Aim: This study assessed the influence of sociodemographic factors on IPTp-SP...

Open access Research Article 10.9734/ajmpcp/2026/v9i2466

Adoptive Cellular Immunotherapy in Glioblastoma: Mechanistic Insights, Clinical Progress, and Future Directions of CAR-T and TIL Therapies

Alper DEMIREZEN & Gizem Nur Mutlu · Asian Journal of Medical Principles and Clinical Practice · 2026

Glioblastoma remains the most common and lethal primary malignant brain tumour in adults, and outcomes have changed little despite maximal surgical resection, radiotherapy and temozolomide chemotherapy. Adoptive cellular immunotherapy, principally chimeric antigen receptor T-cell...

Open access Research Article 10.9734/ajmpcp/2026/v9i2464

Proprioceptive Deficits in Cervicogenic Headache: An Open-Source-Verified Systematic Review

Radhika Sinha & Prerna Mohan Saxena · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Cervicogenic headache is a secondary headache disorder attributed to cervical spine or cervical soft-tissue dysfunction. Cervical proprioceptive impairment has been proposed as one mechanism linking neck pain, impaired head-neck orientation, dizziness, postural instab...

Open access Research Article 10.9734/ajmpcp/2026/v9i2465

Lifestyle and Reproductive Risk Factors Associated with Cervical Dysplasia among Women in Rivers State, Nigeria

Ikukaiwe, Juliet Nkechi, B. E. B. Nkwoke & P. O. Chinedu-Eleonu · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Cervical dysplasia remains an important preventable precursor of cervical cancer, particularly in low- and middle-income settings where screening uptake, early detection, and follow-up care remain uneven. Lifestyle behaviours and reproductive exposures may contribute...

Open access Research Article 10.9734/ajmpcp/2026/v9i2463

Influence of Gut Microbes on the Incretin System and Type 2 Diabetes Mellitus: A Critical Narrative Review

S S Sreenvas · Asian Journal of Medical Principles and Clinical Practice · 2026

Type 2 diabetes mellitus remains one of the principal drivers of global non-communicable disease burden, and impaired secretion or action of the incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide is now recognised as a core feature of its p...

Open access Research Article 10.9734/ajmpcp/2026/v9i2462

Nurses Knowledge and Perception on Patient Acuity Tool and Their Relationship with Self-assessed Patient Outcomes in Houston, Texas, United States of America

Raymond. B. Sarmiento & Joseph Michael Manlutac · Asian Journal of Medical Principles and Clinical Practice · 2026

This study assessed registered nurses’ knowledge and perceptions of the Patient Acuity Tool (PAT) and examined their relationship with self-assessed patient outcomes in acute care settings in Houston, Texas, United States. A quantitative descriptive-comparative-correlational desi...

Open access Research Article 10.9734/ajmpcp/2026/v9i2461

Rituximab Infusion-Related Reactions in Routine Clinical Practice: A Retrospective Pharmacovigilance Study from Iraq

Yasser J. H. Alyassery & Riam Diaa · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Rituximab (RTX) is widely used for autoimmune and haematological diseases, but infusion-related adverse drug reactions (ADRs) remain a clinically important safety concern in routine care. Aim: This retrospective pharmacovigilance study described rituximab-associated a...

Open access Research Article 10.9734/ajmpcp/2026/v9i2460

A Systematic Review on Genetic Polymorphisms Associated with Hypertension Risk

Jaiyeoba-Ojigho Jennifer Efe, Omashim Oluwakemi Ochonogor, Chris-Ozoko Ebele Lilian, Ubogu Joseph Afokeoghene, Okolie Emmanuel Ikechukwu, David Chinaecherem Innocent, Innocent Onyesom, Ovuakporaye Simon Irikefe, Okonkwo Charles Chinemerem, Imariabe Nosakhare Samuel, Etugbo Ann Omamuzo, Jeremiah Ogheneyole, Uti Praise Obielumani, Uririoghene Annabel Duruvwe & Anyanwu Chidinma · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Hypertension is a major global public health burden with a significant heritable component. Despite extensive genomic research, evidence linking specific genetic polymorphisms to hypertension risk remains inconsistent, partly due to a lack of diversity in study popula...

Open access Research Article 10.9734/ajmpcp/2026/v9i2459

Bridging the Knowledge - practice Gap in Emergency Care at the Primary Healthcare Level: Evidence from Ahafo Ano North Municipality, Ghana

Asafo, T. A. Adjei, Albert Opoku, Henrietta Delecter Ntow, Augustina Barbara Nkrumah, Raymond Ahenkorah & Yvonne Arhin Sarpong · Asian Journal of Medical Principles and Clinical Practice · 2026

Emergency care at the primary healthcare level is essential for the timely assessment, stabilisation, and referral of patients with acute illnesses and injuries, particularly in rural settings where access to higher-level facilities may be delayed. This study examined emergency c...

Open access Research Article 10.9734/ajmpcp/2026/v9i2458

Effects of the Use of Information and Communication Technology on the Quality of Health Services in Public and Private Health Facilities: A Systematic Review

Chukwuma Chibuike Barnabas, Omosivie Maduka, Barilee B. Baridam, Irima Odo, Daniel Okon, Okongko Aniefiok Dickson & Emmanuel Etim Clement · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Information and Communication Technology is increasingly used in health facilities to support documentation, communication, clinical decision-making, telemedicine, patient engagement, surveillance and health information management. This systematic review examined evid...

Open access Research Article 10.9734/ajmpcp/2026/v9i2457

Therapeutic Effect of Ethanolic Extract of Zingiber officinale (Ginger Rhizomes) on Selected Biochemical Parameters and Some Electrolytes in Male Wistar Rats

Kanayo M. Odia, Akpere Hallo-Rume, Lauritta C. Ndufeiya-Kumasi, Miebaka Beverly Otobo, Victor Eboseyi Ukpebor & Nicholas Asiwe · Asian Journal of Medical Principles and Clinical Practice · 2026

This study evaluated the effect of ethanolic extract of Zingiber officinale (ginger rhizomes) on selected biochemical parameters and electrolytes in male Wistar rats. Twenty healthy adult male Wistar rats weighing about 150 g were randomly assigned to four groups of five rats eac...

Open access Research Article 10.9734/ajmpcp/2026/v9i2456

Clinical Impact of Rifaximin in Liver Cirrhosis: A Critical Review

Shariya Tanaaz, K. Akash, Nabeeha Zufi, Nabila Fathima & E. Vyshnavi · Asian Journal of Medical Principles and Clinical Practice · 2026

Liver cirrhosis represents a major contributor to global morbidity and mortality, characterised by progressive hepatic fibrosis, portal hypertension, and susceptibility to life-threatening complications including hepatic encephalopathy (HE), spontaneous bacterial peritonitis (SBP...

Open access Research Article 10.9734/ajmpcp/2026/v9i2455

Features of Early Osteoarthritis and Synovitis against the Background of Metabolic Syndrome: A Cross-Sectional Study

Nabiyeva Dildora Abdumalikovna, Abdurazzakova Dilrabo Seytbayevna, Matchanov Seytbay Xudoybergenovich, Tashpulatova Maktuba Muhamedali Qizi & Xo’shnayev Mahmud Almardon O’g’li · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Early knee osteoarthritis may present with pain, stiffness, and functional limitation despite minimal radiographic changes. Metabolic syndrome may contribute to a more symptomatic and inflammatory disease pattern. Objective: This cross-sectional study evaluated the cl...

Open access Research Article 10.9734/ajmpcp/2026/v9i2453

Effectiveness of Strategies to Enhance Patients’ Compliance with Clinical Appointments: A Systematic Review

Oji-Nelson Marvelous Kelechi, Best Ordinioha, Orieke Rebecca Kalu, Irima Odo & Daniel Okon · Asian Journal of Medical Principles and Clinical Practice · 2026

Missed clinical appointments remain an important barrier to continuity of care, timely clinical review, and efficient use of health service resources. This systematic review examined strategies used to improve patients’ compliance with scheduled clinical appointments across globa...

Open access Research Article 10.9734/ajmpcp/2026/v9i2454