Background: Diabetes mellitus (DM) is a progressive metabolic disorder characterised by persistent hyperglycaemia, impaired β-cell function, chronic inflammation and oxidative stress. Current antidiabetic therapies improve glycaemic status but may not fully address inflammatory a...
Open access
Research Article10.9734/ajrre/2026/v9i1134
Background: Female pubertal onset is a complex, multifactorial biological event with substantial global variation. Secular trends show progressive earlier thelarche and menarche across continents, yet biochemical thresholds for diagnosing pubertal onset and central precocious pub...
Open access
Research Article10.9734/ajrre/2026/v9i1132
Objective: To assess clinicians’ perspectives on the use of fixed-dose combinations (FDCs) and triple therapy in type 2 diabetes mellitus (T2DM) in Indian settings, with a focus on therapeutic preferences and perceived clinical benefits. Methods: The cross-sectional survey was co...
Open access
Research Article10.9734/ajrre/2026/v9i1130
This study investigated the effects of Musa acuminata Cavendish and Allium sativum aqueous extracts, both individually and in combination, on streptozotocin-induced type 2 diabetes in Wistar rat. A total of thirty (30) male Wistar rats were used in this study and were divided int...
Open access
Research Article10.9734/ajrre/2026/v9i1129
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycaemia due to defects in insulin secretion, insulin action, or both, and it remains a major global public health challenge, with India contributing a substantial share of the overall disease bur...
Open access
Research Article10.9734/ajrre/2026/v9i1128
Background: This study is a systematic review focusing on the effects of tartrazine and carmoisine azo dyes on lipid, oxidative stress, and reproductive endocrine disruptions in rats. Method: We systematically reviewed studies published between 1972 and 2026 using keywords and sh...
Open access
Research Article10.9734/ajrre/2026/v9i1127
Obesity is a critical factor to enhance the risk of T2DM and other comorbidities. Diabesity a metabolic disorder due to obesity and insulin-resistance (IR), is a global health concern.T2DM a condition of chronic decreased insulin sensitivity or insulin resistance (IR) and loss of...
Open access
Research Article10.9734/ajrre/2026/v9i1126
Background: The relationship between hormones and cancer development constitutes one of the most clinically consequential intersections in modern oncology. Sex hormones, mainly oestrogen, progesterone, and androgens, play a significant role in the onset, development, and advancem...
Open access
Research Article10.9734/ajrre/2026/v9i1125
Introduction: Thyroid hormones perform various metabolic functions, including regulating lipids, carbohydrates, protein, electrolytes, and mineral metabolism. Some micronutrients, including zinc and magnesium, have been implicated in the accurate functioning of some enzymes invol...
Open access
Research Article10.9734/ajrre/2026/v9i1124
Background: Obesity represents a major global heath challenge because of the established health risks and substantial increase in its prevalence in children and adults in both developed and developing countries. Paediatric obesity has become a thing of concern in the last few dec...
Open access
Research Article10.9734/ajrre/2026/v9i1123
Background: Paragangliomas are rare neuroendocrine tumors arising from extra-adrenal chromaffin tissue of the autonomic nervous system. Functioning paragangliomas may secrete catecholamines, leading to hypertensive crises and serious cardiovascular and cerebrovascular complicatio...
Open access
Research Article10.9734/ajrre/2026/v9i1122
Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age, yet global awareness remains low, particularly among young women. The consequences of insufficient PCOS knowledge among female undergraduates extend beyond delayed dia...
Open access
Research Article10.9734/ajrre/2026/v9i1121
Pheochromocytoma is a rare cause of secondary hypertension in children and adolescents. We report a case of a 15-year-old girl who presented with recurrent adrenergic spells and severe hypertension, subsequently diagnosed with bilateral pheochromocytoma associated with Von Hippel...
Open access
Research Article10.9734/ajrre/2026/v9i1120
Aim: To assess serum phosphate and luteinizing hormone (LH) levels in HIV patients on antiretroviral therapy (ART) attending Rivers State University Teaching Hospital in Port Harcourt, Nigeria. Study Design: Analytical cross-sectional study. Place and Duration of Study: Rivers St...
Open access
Research Article10.9734/ajrre/2025/v8i1119