Background: The pathogenesis of hepatitis B virus (HBV) infection is based on the interactions between HBV replication and immune responses. The aim of this study was to look into the immune-regulatory functions of IL-12, TNF-α, IFN-γ, IL-8, and IL-10 in chronic hepatitis B (CHB)...
Most Neuroendocrine tumours (NETs) are of digestive origin (70%), they can involve from any organ of the digestive system. The small intestine and rectum are the most common locations, (small intestine 30%, colorectal 30%, appendix 20%, pancreas 10%, stomach 5%). The clinical pre...
Background: Botox toxin treatment is an effective method in chronic anal fissures. Although the risk of anal incontinence is very low in botox toxin treatment, the recurrence rates are very high. Therefore, it is necessary to develop new application methods that can reduce the re...
Background: In the era of COVID-19 pandemic, various procedures have been carried out to prevent the virus transmission, and emergency surgery on COVID-19 patients is reconsidered and extremely challenging. One of the most common emergency procedures is gastrointestinal surgery. ...
Aim: To study the incidence of various pathologies in upper gastrointestinal endoscopy (UGIE) and the correlation of the endoscopic findings with histopathological interpretation of the endoscopic biopsies. Incidence of H. pylori bacteria in patients with gastritis was also noted...
Aims: Mean platelet volume (MPV) has been a potential biomarker for disease activity of inflammatory bowel disease (IBD), with an observed inverse relationship between MPV and disease activity. The study aims to investigate MPV as a complementary biomarker for disease activity in...
Background: Rubber band ligation is widely practiced for treatment of haemorrhoidal disease. Aims: To study the early and long-term outcome of rubber band ligation for grades I-III haemorrhoids. Study Design: A prospective cohort study. Place and Duration of Study: Oak Endoscopy...
Lead poisoning has been recognized as a major public health risk. We present a case of middle aged female, who presented with recurrent episodes of severe abdominal pain , which remains obscure even after thorough clinical evaluation and extensive investigations. Lastly, blood le...
Aims: This study was conducted to evaluate the prevalence and predictors of Rotavirus infection among children aged 0-5 years with gastroenteritis in 2 selected healthcare centres in Keffi, Nigeria. Study Design: The study was a cross sectional study. Place and Duration of Study:...
Introduction and Aims: Resins are non-absorbable medications that facilitates ion exchange and are commonly used in the treatment of hyperkalemia. Crystal deposition by these resins could result in and aggravate colonic mucosal damage. This rare but serious adverse event is under...
Background: Along with ulcerative colitis, Crohn’s disease is one of a group disease known as inflammatory bowel disease. Crohn’s disease is a rare in pediatric population. It most common through people who are between the ages fifteen and thirty. Manifestation in pediatric are m...
Introduction and Aims: Gastrointestinal toxicity resulting in diarrhea is a common side effect in patients taking Mycophenolate mofetil (MMF). The challenge is in making the decision to pursue further workup being mindful of malignancy and opportunistic infection in these group o...
Aims: To determine mean serum B-type natriuretic peptide (BNP) levels and their relationship with the severity of disease in patients with chronic liver disease (CLD). Study Design: Descriptive cross-sectional study Place and Duration of Study: Department of Medicine, Unit-2, Ji...
Aims: This study was conducted to evaluate the prevalence and socio-demographic determinants of Ascariasis among primary school pupils in Central Nigeria. Study Design: The study was a cross sectional study. Place and Duration of Study: Keffi, Nasarawa State, between March and Ju...
Aim: Stapled haemorrhoidopexy (SH) is one of the commonly performed procedure for grade 3 haemorrhoids. High-risk surgical patients require additional care and are reported to have high morbidity. The present study is aimed to analyze the outcome of SH in high-risk patients. Stud...