The kidneys play a vital role in our overall health and well-being. Their ability to filter waste, reabsorb essential nutrients and maintain a balance of fluids and electrolytes in our body is essential for our health. However, various factors such as age-related changes, exposur...
Cheikh Sara, Kharrat Assia, Soldi Chaimaa, Elouati Achraf, Elkhayat Selma, Mtioui Nouafal, Zamd Mohamed Ali, Medkouri Ghizlaine & Benghanem Mohamed·Asian Journal of Research in Nephrology·2024
Nutcracker syndrome results from compression of the left renal vein (LRV), usually in the range formed by the abdominal aorta and the superior mesenteric artery (SMA), leading to stenosis of the aorto-mesenteric part of the left renal vein and dilation of its distal part. The sym...
Aim: The study aims to assess the effect of Vernonia amygdalina on some kidney function parameters in Alloxan – induced diabetic rats. Study Design: Experimental study. Place and Duration of Study: The study was conducted at the Departments of Biochemistry and Histology, Imo Sta...
Z. Benamara, R. Alafifi, S. Hamine, A. Magramane, G. Medkouri, S. S. Elkhayat, M. Zamd, N. Mtioui, M. G. Benghanem & L. Barrou·Asian Journal of Research in Nephrology·2023
Aims: Acute kidney injury (AKI) was noticed as a common complication of COVID-19 infection, associated with increased intensive care unit (ICU) admissions and mortality. Not surprisingly, Kidney transplant recipients appeared to be at higher risk either for severe COVID-19 infect...
Researchers have struggled in recent years to anticipate how oral drugs would be absorbed by people, and numerous permeability study approaches have been created for a variety of uses, including biowaiver procedures. The Single-Pass Intestinal Perfusion (SPIP) technique, used on...
Gitelman Symdrome is a type of inherited tubulopathy that results in hypokalemia, hypomagnesemia, hypocalciuria and metabolic alkalosis. It is generally due to loss of function mutation of SLC12A3 Gene. The prevalence is estimated at approximately 1:40,000. In the majority of cas...
Z. Benamara, S. Hamine, I. Elmokhtari, S. S. Elkhayat, G. Medkouri, M. Zamd, N. Mtioui, M. G. Benghanem & L. Barrou·Asian Journal of Research in Nephrology·2023
Aims: Kidney transplant patients are particularly at risk of developing dreadful complications due to any infection, given the daily intake of immunosuppressive drugs, Covid- 19 is no exception. However the obstructive cause has never been described to the best of our knowledge R...
Z. Benamara, S. Hamine, S. Nahmed, S. S. Elkhayat, G. Medkouri, M. Zamd, N. Mtioui, M. G. Benghanem, D. Laoudiyi, K. Chbani & S. Salam·Asian Journal of Research in Nephrology·2023
Aims: Caroli and Cacchi Ricci are two rare diseases but frequently associated. We report the case of a young girl who presented these exceptional entities. Results: We report the case of a 14-year-old girl with no particular pathological history, who presented to the emergency ro...
Cardiac involvement is the leading cause of mortality and morbidity in patients undergoing chronic hemodialysis. Therefore, echocardiography is the preferred diagnostic test. Our study aims to describe the different cardiac lesions observed on transthoracic echocardiography and i...
Thrombotic microangiopathy (TMA) secondary to anticancer drugs exhibits varying clinicopathological presentation and severity, with variable response and prognosis upon discontinuation of the medication. We conducted a retrospective, monocentric, descriptive, and analytical study...
Calciphylaxis is a condition that causes cutaneous necrosis, which primarily affects patients with end-stage renal disease undergoing dialysis. Histologically, this condition is characterized by subintimal calcific deposits in small-caliber arteries, leading to luminal obstructio...
Dysfunctions of the AVF such as thrombosis or stenosis are frequent complications. One of the main factors at the origin of these dysfunctions is an anomaly of coagulation dependent on overactive platelets during chronic renal insufficiency. Younger, more excitable platelets are...
This study describes a comparison between blood and urine profiles of Remogliflozin simultaneously in a rat pharmacokinetic study using a simple UPLC method. Quantitative determination of Remogliflozin is performed in rat blood with the recovery values in the range of 85-115%. A...
The Term undifferentiated connective tissue disease is used to define conditions characterised by the presence of signs and symptoms suggestive of a systemic autoimmune disease that does not satisfy the classification criteria for defined connective tissue diseases (CTD) such as...
Introduction: Diabetic nephropathy is a leading cause of end-stage renal failure and chronic kidney disease throughout the globe. Despite the fact that much research has been conducted in both basic science and clinical therapeutics to better understanding of the biology of diabe...