Skip to content

All published articles 154

Cancer Epidemiology in Zimbabwe: Insights from GLOBOCAN 2020 Estimates on Incidence, Mortality, and Risk Modeling

Nyasha Chin'ombe, Senyefia Bosson-Amedenu, Anthony Joe Turkson, Christiana Cynthia Nyarko, Ezekiel Nii Noye Nortey, Lilia Ghorbal & Noureddine Ouerfelli · Asian Oncology Research Journal · 2026

Zimbabwe, a landlocked, lower-middle-income country in Southern Africa, faces a significant cancer burden. The present study aims to provide a quantitative analysis of cancer epidemiology in Zimbabwe for 2020 using data from the Global Cancer Observatory (GCO). Focusing on the 10...

Open access Research Article 10.9734/aorj/2026/v9i1156

Cutaneous Nasal Metastasis of Gastric Carcinoma: An Unusual Case with Review of Literature

Sharath K. Krishnan, M. T. Suma & Bhavya P. Mohan · Asian Oncology Research Journal · 2026

Cutaneous metastasis from gastric adenocarcinoma is uncommon and usually indicates advanced disease. Nasal involvement is particularly unusual and may clinically mimic benign, inflammatory, infectious, or primary cutaneous lesions. This case report describes a 56-year-old man wit...

Open access Research Article 10.9734/aorj/2026/v9i1154

Influence of Anaesthetic Technique on Postoperative Cancer Outcomes in Adult Patients Undergoing Solid Tumour Surgery: A Systematic Review of Observational Evidence with an Updated Synthesis of Randomised Trials

Nangah Tabukum, Mohammed Omar Almosa, Radiya Almosa & Morad Marikh · Asian Oncology Research Journal · 2026

Background: Perioperative anaesthetic technique has been proposed as a modifiable determinant of long-term cancer outcomes because propofol and volatile anaesthetics have different immunological and tumour-biological effects. Earlier clinical evidence was dominated by retrospecti...

Open access Research Article 10.9734/aorj/2026/v9i1155

Genome Editing in Oncology: A Critical Appraisal of CRISPR-Based Approaches to Tumour Evolution

Nalam Vineela Nirmala, Muthineni Pradeep Kumar, Avanigadda Niharika, Garaga Kavya Chandrika, Tsaliki Durga Veera Manikanta Sathish & Lingineni Mani Deepa Chandrika · Asian Oncology Research Journal · 2026

Clustered regularly interspaced short palindromic repeats (CRISPR) technologies have been described as precision instruments capable of countering the evolutionary adaptability that underlies treatment failure in cancer. The evidence supporting that description is uneven. This cr...

Open access Research Article 10.9734/aorj/2026/v9i1153

Extracellular Matrix Mechanics in Cancer: Mechanotransduction, Cellular Phenotype, and Therapeutic Resistance

Sharmy Saimon Mano · Asian Oncology Research Journal · 2026

Abnormal extracellular matrix (ECM) stiffening emerges chiefly from enhanced matrix deposition and remodelling by cancer cells and cancer-associated fibroblasts. This biomechanical alteration activates mechanosensitive pathways, principally through integrin-mediated adhesion comp...

Open access Research Article 10.9734/aorj/2026/v9i1152

CEA-Discordant Progression in Metastatic Rectal Cancer: A Case Report

Girin Ray, Kumar Kishlay & Mayur Bahan Mukherjee · Asian Oncology Research Journal · 2026

Background: Metastatic rectal carcinoma requires coordinated multimodal management, with treatment decisions informed by disease extent, clinical status, pathology, imaging, and molecular findings. Case Presentation: A 61-year-old woman presented in November 2022 with progressive...

Open access Research Article 10.9734/aorj/2026/v9i1150

Irreversible Bilateral Blindness from Compressive Optic Neuropathy Caused by a Left Sphenoid Wing Meningioma Despite Radiological Response to Radiotherapy: A Case Report

Lotfi Chaabani, Ines Bouallegui & Mohamed Said · Asian Oncology Research Journal · 2026

Aims: To highlight the risk of irreversible blindness from delayed recognition of compressive optic neuropathy caused by a sphenoid wing meningioma and to emphasise that radiological tumour control does not necessarily imply visual recovery once optic atrophy is established. Pres...

Open access Research Article 10.9734/aorj/2026/v9i1151

Clinico-Epidemiological Profile of 834 Oral Submucous Fibrosis Cases: A Retrospective Institutional Study

M S Mandale, Akanksha Bhardwaj, Jayanti Humbe, Vaishali Nandkhedkar & Savita Wagh · Asian Oncology Research Journal · 2026

Background: Oral submucous fibrosis (OSMF) is a chronic fibrotic oral potentially malignant disorder strongly associated with areca-nut exposure. Objective: To describe the demographic profile, principal recorded habits, chief complaints, associated oral findings, and documented...

Open access Research Article 10.9734/aorj/2026/v9i1148

Serum p27, p53, Lactate Dehydrogenase and Alkaline Phosphatase as Candidate Biomarkers in Breast Cancer in Port Harcourt, Nigeria

Prince Nnabugo Ali-Diogu, Onengiyeofori Ibama & Adline Erinma Ben-Chioma · Asian Oncology Research Journal · 2026

Background: Breast cancer remains a major cause of morbidity and mortality among women, with a substantial burden in resource-limited settings where access to advanced diagnostic facilities may be constrained. Although p27 and p53 are important tumour suppressor proteins and lact...

Open access Research Article 10.9734/aorj/2026/v9i1149

Definitive Radiotherapy for Bilateral Carotid Body Tumors: A Case Report with 3.5 Years Follow-Up

Madhuri Karyampudi, Rajeev Guntupalli & A. K. Raju · Asian Oncology Research Journal · 2026

Carotid body tumours (CBTs) are rare, slow-growing neuroendocrine neoplasms arising at the carotid bifurcation, and bilateral disease is uncommon. This case report describes the use of definitive radiotherapy for bilateral Shamblin type II CBTs in a 60-year-old man presenting wit...

Open access Research Article 10.9734/aorj/2026/v9i1147

Knowledge, Attitudes, and Acceptance of Human Papillomavirus Vaccination Among Women of Reproductive Age Attending a Tertiary Hospital in Southeast Nigeria

Emmanuel M. Akwuruoha, David O. Akwuruoha, Vanessa A. Chigbundu & Augustine I. Airaodion · Asian Oncology Research Journal · 2026

Background: Human papillomavirus (HPV) infection is a major cause of cervical cancer, particularly in low- and middle-income countries where access to preventive services is limited. Despite the proven effectiveness of HPV vaccination in preventing HPV-related diseases, vaccine u...

Open access Research Article 10.9734/aorj/2026/v9i1146

Pattern of Cancer and Treatment Modalities among Adult Cancer Patients in Tertiary Hospitals of Bayelsa and Rivers States, Nigeria

Tariebi Katherine Owei-Tongu, Ebiowei John, Happiness Biobelene Amakiri, Ogbonna Nnenna Salomey, Marie Therese Teibowei, Zar, Vershima Daniel, Emmanuel Etim Clement & Georgeline Nliam-Giesen · Asian Oncology Research Journal · 2026

Background: Facility-based evidence on cancer patterns and treatment profiles is important for planning oncology services in Nigeria. This study described cancer types, disease stage, and treatment modalities among adults managed in two tertiary hospitals in Bayelsa and Rivers St...

Open access Research Article 10.9734/aorj/2026/v9i1144

Hyalinizing Clear Cell Carcinoma of Palate: A Systematic Review

Ayushi Goyal, Jayanti G. Humbe, Mandakini Mandale, Vaishali Nandkhedkar & Savita Wagh · Asian Oncology Research Journal · 2026

Hyalinising clear cell carcinoma (HCCC) is a rare, low-grade malignant tumour of minor salivary gland origin that most commonly affects the palate. This systematic review analysed the demographic profile, clinical presentation, diagnostic features, management, and outcomes of rep...

Open access Research Article 10.9734/aorj/2026/v9i1145

Primary Conjunctival Embryonal Rhabdomyosarcoma in a 19-Year-Old Man: A Case Report

Lotfi Chaabani, Ines Bouallegui, Merieme Kalou, Saad Elbaraki, Laila Ferchichi & Abdelghani Chaabani · Asian Oncology Research Journal · 2026

Background: Primary conjunctival embryonal rhabdomyosarcoma is an exceptionally uncommon ocular surface malignancy that can resemble benign conjunctival lesions. This report describes its clinical, histopathological, immunohistochemical, radiological and staging features in a you...

Open access Research Article 10.9734/aorj/2026/v9i1143

Renal Cell Carcinoma with Metastases to Oral Cavity: A Systematic Review

Vaishnavi Marge, Mandakini Mandale, Jayanti Humbe, Vaishali Nandkhedkar & Savita Wagh · Asian Oncology Research Journal · 2026

Introduction: Metastasis of renal cell carcinoma (RCC) to the oral cavity is uncommon but clinically significant and often presents with non-specific features resembling benign or reactive oral lesions. In some patients, the oral lesion may be the first clinical manifestation of...

Open access Research Article 10.9734/aorj/2026/v9i1142