Aim: The risk of cancer during Grave’s Disease (GD) is currently demonstrated by several studies. This risk is particularly high for thyroid cancer. However, cancer in newly diagnosed GD remains rare. We report early malignant transformation of a newly diagnosed GD with multiple...
Background and Objective: Cisplatin (CP), a potent antineoplastic drug and its anti-cytotoxic activity is used to treat many cancer types. The present study aimed to examine the possible modifying effects of ginseng extract against spleen oxidative stress and injury induced by Ci...
Maha El-Gayyar, Manar Sallam, Mohamed Khaled, Mohamed El-Mougy, Amany El-Hawwary, Amal Halim, Hala El. Shenshawy & Adel El-Badrawy·Asian Oncology Research Journal·2020
Background: Langerhans cells histiocytosis (LCH) is a rare disease characterized by the uncontrolled proliferation of Langerhans cells (LCs). This study aimed to explore the clinic-epidemiological and pathological data of that disease in our population. Methods: Sixteen patients...
Background and Objective: The present study aimed to examine the possible modifying effects of ginseng extract against both liver and kidney injuries induced by Cisplatin in rats. Materials and Methods: A total of 24 male albino rats were equally divided into six groups; the firs...
IL-6 is a cytokine with multiple protumorigenic effects, making it an interesting therapeutic target. IL-6 inhibitors with an acceptable safety profile had been developed and tested in experimental and clinical trials. However, the outcomes were not as expected theoretically. Pos...
Aim: To study the clinical and demographic characteristics of cancers of uterine cervix with histology other than SCC and AC at a tertiary referral hospital in eastern India. Study Design: Retrospective study. Place and Duration of Study: Tata Medical Center, Kolkata, India from...
Background: Down syndrome children with cancer are susceptible to nutritional depletion due to the combined effects of the malignant disease and its treatment. The assessment of the nutritional status of pediatric oncology patients on admission to hospital is crucial, as nutritio...
Aims: The aim of this study was to estimate the awareness and knowledge of breast cancer and breast self-examination and to estimate the effectiveness of intervention on awareness and knowledge of breast cancer (BC) and breast self-examination (BSE) among the potentially, at risk...
Prostate cancer risk factors gain more awareness in the world nowadays, due to the increasing incidents, which vary among different ethnic groups. Researches about genetic risk factors might help for more understanding of the initiation and development of prostate cancer and esti...
The beneficial effect of maternal colostrum and milk on the newborn as well as on the nursing mother is well known. However, many other potentially preventive and therapeutic aspects associated with the use of components of these secretions are still partially known and have spar...
Amal F. Gharib, Abdel Rhman Nasser Alghamdi, Mosfer Nasser Alghamdi, Ahmed El Askary & Wael H. Elsawy·Asian Oncology Research Journal·2019
Aim: MicroRNA-221 plays an important role in a number of human malignancies. The present study was conducted to shed light on the role of mir-221in colorectal cancer as regards the initiation of malignant process and progression. Methods: Real-time reverse transcription–polymeras...
Lung cancer is a disease which invades the lung tissue by formation of uncontrolled cell growth, and this may also affect the tissues near the lung. There are a wide range of prognostic factors which determine survival duration of lung cancer patients. Among the most important fa...
The aim of this paper is the review the factors that determine cancer progression which would help in the treatment and diagnosis of the disease. Cancer is a leading life-threatening disease and despite the recent technological advancement, there is still a poor survival rate in...
Aims: Cancer is caused by an imbalance in the rate of proliferation and apoptosis and the positive effect of anticancer therapy is taken into consideration when its ability to initiate apoptosis in cancer cells. In vivo; several experimental models established in experimental ani...
Background and Objective: Cancer is initiated due to abnormalities in the DNA of the affected cells leading to an extra mass of tissue termed a tumor. Breast cancer is the most public cancer amongst women world-wide. The present work is designed to investigate the ameliorating po...