Oladapo Michael Alaba, Obafemi Samuel Olayinka, Olaolu Oyinlola Bilewu & Idowu David Alake·Asian Oncology Research Journal·2025
Breast cancer continues to pose a significant global health burden, impacting women in both industrialized and developing nations. Breast self-examination (BSE) continues to be a cost-effective and convenient approach for the timely detection of breast cancer in Nigeria. Hence, t...
Open access
Research Article10.9734/aorj/2025/v8i1111
Endometrial cancer is the most common gynecological malignancy in developed countries, with rising incidence globally, largely paralleling the epidemic of obesity and metabolic syndrome. Metabolic syndrome, characterized by central obesity, insulin resistance, dyslipidemia, and h...
Open access
Research Article10.9734/aorj/2025/v8i1109
Aims: Breast carcinoma (BC) is the leading cause of tumor burden, with an incidence of 11.8%. The programmed cell death protein 1(PD-1)/programmed death ligand 1 (PD-L1) pathway represents an adaptive immune resistance mechanism that tumor cells exert. Recent updates in the treat...
Open access
Research Article10.9734/aorj/2025/v8i1108
Background: Malignant thyroid disease is an emerging yet underreported public health issue in Nigeria and Sub-Saharan Africa. Although generally associated with a favourable prognosis when detected early, substantial gaps in diagnosis, treatment, and data reporting hinder optimal...
Open access
Research Article10.9734/aorj/2025/v8i1107
Renal medullary carcinoma is an uncommon malignancy that occurs predominantly in young males with sickle cell trait. This cancer is driven by the loss of a tumor suppressor gene called SMARCB1 which is mutated in a variety of rare childhood cancers. Due to its aggressive nature,...
Open access
Research Article10.9734/aorj/2025/v8i1106
Background: There is a multitude of problems encountered during the management of critical conditions in low-resource settings. Reducing the administration of brachytherapy from 3 to 2 fractions will assist cervical cancer patients by decreasing the treatment costs and as well as...
Open access
Research Article10.9734/aorj/2025/v8i1105
The dynamic interaction between cancer stem cells (CSCs) and the tumor microenvironment (TME) is increasingly recognized as a key driver of tumor progression, metastasis, and therapeutic resistance. Disrupting this molecular crosstalk offers a promising strategy to improve cancer...
Open access
Research Article10.9734/aorj/2025/v8i1104
Aims: This study aims to identify non-toxic, flavonoid-derived phytochemicals as potential inhibitors of Matrix Metalloproteinase-1 (MMP-1), a key enzyme involved in breast cancer invasion and metastasis. Study Design: An integrative in silico approach was adopted, incorporating...
Open access
Research Article10.9734/aorj/2025/v8i1103
This is hospital based descriptive retrospective case study conducted in isotope hospital in Khartoum state, during the period from March 2019 to June 2019. The study aimed to detect the expression Cytokeratin 5/6 and Smooth Muscle Actin in Triple Negative breast carcinoma tumo...
Open access
Research Article10.9734/aorj/2025/v8i1102
B. Sunjidmaa, Dylan Treger, Xiaoxiao Jia, Jessica Hui, Taivanbat Ganbaatar, Bat-erdene Ganbaatar, Zhaohui Ma & Mizhou Hui·Asian Oncology Research Journal·2025
Background: Advanced lung cancer and its associated pain symptoms place a significant burden on patients. A 35 kDa hyaluronan fragment (HA35) has been confirmed to effectively alleviate inflammatory and neuropathic pain in palliative care settings. This single-arm, prospective pi...
Open access
Research Article10.9734/aorj/2025/v8i1101
Aims: Carotid body tumors (CBTs) are rare, non-chromaffin paragangliomas that typically require surgical resection. However, recurrent cases pose significant challenges. This report describes the successful management of a recurrent CBT with external beam radiotherapy (EBRT), hig...
Open access
Research Article10.9734/aorj/2025/v8i1100
Niragh Sikdar, Brahma Kumar Bhattacharyya, Megha Mahida, Sanskruti Shailesh Rathod, Krithi Pichiah John & Anushka Baidya·Asian Oncology Research Journal·2025
The rare form of thymic cancer demonstrates high aggressiveness in its behavior. A 55-year-old male patient with stage III thymic carcinoma received extensive surgical treatment followed by cisplatin-etoposide chemotherapy. The patient received optimal treatment from three medica...
Open access
Research Article10.9734/aorj/2025/v8i199
Palliative radiotherapy relieves distressing symptoms and helps to manage localized tumor growth when curative treatment is not possible. The study aims to determine that a palliative regimen of 24 Gy in 4 fractions in 4 weeks, once weekly fractionation can achieve a similar resp...
Open access
Research Article10.9734/aorj/2025/v8i198
Cancer resistance to conventional therapies remains a significant challenge in oncology, leading to treatment failure and poor patient outcomes. Immunotherapy has emerged as a promising approach to overcome resistance by harnessing the body's immune system to recognize and elimin...
Open access
Research Article10.9734/aorj/2025/v8i197
Oral and maxillofacial cancers (OMC) remain a significant global public health concern due to their high incidence, mortality rates, and long-term morbidity. Key risk factors, including tobacco use, alcohol consumption, betel quid chewing, and human papillomavirus (HPV) infection...
Open access
Research Article10.9734/aorj/2024/v7i195