Aims: Xenograft models, namely heterotransplantation of human cancer cells or tumor biopsies into immunodeficient rodents are the major preclinical approach for the development of novel cancer therapeutics. However, in these models the animals must be used only after the severe s...
Open access
Research Article10.9734/BJMMR/2012/1072
Vladimir P. Baklaushev, Nadezhda Ph. Grinenko, Eugene B. Tsitrin, Michael S. Belyaev, Vladimir E. Mukhin, Gaukhar M. Yusubalieva, Olga I. Gurina, Svetlana N. Bykovskaya & Vladimir P. Cheknonin·Journal of Advances in Medicine and Medical Research·2011
Downregulation of gap junctions by monoclonal antibodies against the second extracellular loop of connexin-43 (E2Cx43) was studied in a passaged culture of astrocytes. The results of confocal laser scanning microscopy demonstrated that, after two hours of coincubation of cells lo...
Open access
Research Article10.9734/BJMMR/2011/290
Alexander V. Averyanov, Anatoly G. Konoplyannikov, Fedor G. Zabozlaev, Anastasia V. Sorokina, Mikhail A. Konoplyannikov, Vladimir P. Baklaushev & Robert I. Khabazov·Journal of Advances in Medicine and Medical Research·2016
Aims: Sepsis is a leading cause of mortality in intensive care units. Development of new strategies such as the therapy with mesenchymal stem cells (MSC) appears beneficial for the treatment of sepsis. In this study we evaluated anti-septic effects of rat MSCs and recombinant ery...
Open access
Research Article10.9734/BJMMR/2016/23761