Background: Oral squamous cell carcinoma is the most prevalent malignancy in the head and neck area, arising from various sites, including the lip, tongue, gingiva, cheek, and floor of the mouth. As the tumours grow, they invade the adjacent tissues and can spread to the cervical...
Open access
Research Article10.9734/aorj/2025/v8i1115
Aims: to investigate the correlation between m6A methylation and clinical characters of NPC patients, as well as, it`s development and progression, because N6-methyladenosine (m6A) methylation was a post-transcriptional modification that regulates gene expression, and had been im...
Open access
Research Article10.9734/aorj/2025/v8i1114
Bone marrow metastasis from solid tumours typically occurs in advanced disease stages and rarely presents as the initial clinical manifestation. Herein, we are reporting that a 65-year-old man was admitted with a history of gum bleeding during dental work. His medical history was...
Open access
Research Article10.9734/aorj/2025/v8i1113
Background: Cervical cancer remains a leading cause of cancer-related morbidity and mortality among women in Sub-Saharan Africa (SSA). Limited access to preventive services, low awareness, and infrastructural challenges contribute to disproportionately high incidence and mortalit...
Open access
Research Article10.9734/aorj/2025/v8i1112
Chimeric Antigen Receptor (CAR) T cell therapy has revolutionized cancer treatment, delivering high remission rates in hematologic malignancies such as B-cell acute lymphoblastic leukemia and diffuse large B-cell lymphoma. By engineering T cells to recognize tumour-associated ant...
Open access
Research Article10.9734/aorj/2025/v8i1110
Oladapo Michael Alaba, Obafemi Samuel Olayinka, Olaolu Oyinlola Bilewu & Idowu David Alake·Asian Oncology Research Journal·2025
Breast cancer continues to pose a significant global health burden, impacting women in both industrialized and developing nations. Breast self-examination (BSE) continues to be a cost-effective and convenient approach for the timely detection of breast cancer in Nigeria. Hence, t...
Open access
Research Article10.9734/aorj/2025/v8i1111
Endometrial cancer is the most common gynecological malignancy in developed countries, with rising incidence globally, largely paralleling the epidemic of obesity and metabolic syndrome. Metabolic syndrome, characterized by central obesity, insulin resistance, dyslipidemia, and h...
Open access
Research Article10.9734/aorj/2025/v8i1109
Aims: Breast carcinoma (BC) is the leading cause of tumor burden, with an incidence of 11.8%. The programmed cell death protein 1(PD-1)/programmed death ligand 1 (PD-L1) pathway represents an adaptive immune resistance mechanism that tumor cells exert. Recent updates in the treat...
Open access
Research Article10.9734/aorj/2025/v8i1108
Background: Malignant thyroid disease is an emerging yet underreported public health issue in Nigeria and Sub-Saharan Africa. Although generally associated with a favourable prognosis when detected early, substantial gaps in diagnosis, treatment, and data reporting hinder optimal...
Open access
Research Article10.9734/aorj/2025/v8i1107
Renal medullary carcinoma is an uncommon malignancy that occurs predominantly in young males with sickle cell trait. This cancer is driven by the loss of a tumor suppressor gene called SMARCB1 which is mutated in a variety of rare childhood cancers. Due to its aggressive nature,...
Open access
Research Article10.9734/aorj/2025/v8i1106