Ugochukwu Samuel Aguwa, Okeke Somadina Nnamdi, Ezejindu Darmian Nnabuihe, Eze Chinyere Elizabeth, Azurunwa Ogechi, Obinwa Benedict Nzube, Ovie Ogbo. Felix, Obi Kelvin Chukwuemeka, Onwuelingo Sopuru, Okonkwo David, Doris Ogbuokiri & Okeke Chijioke·Journal of Advances in Medical and Pharmaceutical Sciences·2020
Chloroform inhalation is a common method of rodent euthanasia in Nigeria for research purposes. This work is designed to evaluate the consequence of this method of sacrifice on the cerebellum and hippocampus of Wistar rats. Twenty male Wistar rats weighing between 160 and 180 wer...
Open access
Research Article10.9734/jamps/2020/v22i630176
Aim: Evaluate the protective effects of palm oil on renal parameters after dichlorvos toxicity in albino rats. Study Design and Methodology: The study consisted of 3 phases: The acute study which lasted for 24 hours, the sub-acute study which lasted for 14 days and the sub chroni...
Open access
Research Article10.9734/jamps/2020/v22i630175
Background and Objective: Modified-release tablet of theophylline that can increase its usefulness despite narrow therapeutic index and short half-life, is being formulated. However, the rate and extent of release of a sustained-release delivery system can be affected by some fac...
Open access
Research Article10.9734/jamps/2020/v22i530173
Background: One of the consequences of increasing urbanization is that many people eat processed foods that contain various chemical substances applied as additives. Some of them may have the ability to suppress male fertility. Aims: To determine the effects of sodium benzoate (N...
Open access
Research Article10.9734/jamps/2020/v22i530174
Microbiome that reside in the human gut are key contributors to host metabolism and are considered potential sources of novel therapeutics in metabolic disorders. This review discusses the role of gut microbiome in the pathogenesis of obesity, type 2 diabetes mellitus (T2DM), chr...
Open access
Research Article10.9734/jamps/2020/v22i530171
Lead a free-radical generating agent is a multi-systemic toxicant which affects major body systems especially the hepatic axis. Several natural products rich in antioxidant agents have been used to ameliorate lead toxicity. Vitamin C present abundantly in palm wine has been noted...
Open access
Research Article10.9734/jamps/2020/v22i530169
Aims: To study the In-vivo anti-typhoid activities of ethanol stem bark extract of Bridelia ferruginea in albino rats infected with Salmonella typhi. Study Design: Experimental design. Place and Duration of Study: Department of Microbiology, Federal University of Technology, Akur...
Open access
Research Article10.9734/jamps/2020/v22i530170
Aims: The study was aimed at determining the relationship between plasma homocysteine level and indices of severity in heart failure patients seen at a referral teaching hospital in Gombe, Northeast Nigeria. Study Design: It was a hospital based cross-sectional study conducted on...
Open access
Research Article10.9734/jamps/2020/v22i430168
Aims: Malaria in pregnancy is a weighty health problem in sub-Saharan Africa where 90% of the global malaria burden occurs, therefore there is urgent need for more researches on malaria in pregnancy to reduce its mortality and morbidity. Anaemia, body mass index and risk factors...
Open access
Research Article10.9734/jamps/2020/v22i430167
The use of test batteries has been suggested as a means to enhance throughput, to broaden the spectrum of anxiety parameters detectable and to minimise the numbers of experimental animals required in behavioural studies. This study was undertaken to determine the sensitivity of t...
Open access
Research Article10.9734/jamps/2020/v22i430166