The buccal region of oral cavity is a interesting target for the drug of choice administration. To increase prevent first pass metabolism and bioavailability, Alfuzocin Hydrochloride is embedded in buccal film for a sustained release over a period of 8 hours. The purpose of this...
Open access
Research Article10.9734/jamps/2020/v22i230155
The purpose of this study is to investigate the effects of total methanol leaf-extract of Dialium guineense (Cesalpiniaceae) and its fractions on blood glucose in rat. The fractions of methanol extract were obtained by chromatography Sephadex LH 20 gel, numbered F1 to F5. Experim...
Open access
Research Article10.9734/jamps/2020/v22i230154
Aim: To investigate the levels of total aflatoxin (AF) in herbal medicines from selected vendors in South- Eastern Nigeria. Study Design: This is a cross-sectional study designed to investigate the levels of aflatoxin (AF) mycotoxin in herbal traditional medicines selected random...
Open access
Research Article10.9734/jamps/2020/v22i130152
Background: Cannabis is one of the commonly abused psychoactive substances worldwide. The increasing abuse of this psychoactive substance is recognized as a significant public health problem in many developing countries. A proper assessment of the patterns and trends of cannabis...
Open access
Research Article10.9734/jamps/2020/v22i130153
Introduction: Hyperlipidemia is a leading cause of cardiovascular diseases (CHDs) with treatment ranging from dietary management and the use of antihyperlipidaemic drugs. The desire for anti-hyperlipidaemic drugs with less side effects has led to the screening of medical with ant...
Open access
Research Article10.9734/jamps/2020/v22i130151
The scourge of diabetes has led to an increase in the use of complementary and alternative medicine. The lack of regulation and control leads to the indiscriminate use of these herbals, with potential risk to patients. Aim: This study evaluates the lipidaemic and hepatic status o...
Open access
Research Article10.9734/jamps/2020/v22i130150
Aim: To determine the concentration of Ochratoxin A and Fumonisin B1 mycotoxins in herbal medications available in markets in Ebonyi State. Study Design: This is a cross-sectional study designed to determine the levels of Ochratoxin A and Fumonisin B1 mycotoxins in herbal traditi...
Open access
Research Article10.9734/jamps/2020/v22i130149
Aims: To demonstrate the efficacy of aromatic hydrazide compounds to inhibit growth of Mycobacterium tuberculosis. Study Design: To synthesize tuberculostats and test their antibacterial activity in-vitro. Place and Duration of Study: University of Nebraska, Durham Science Center...
Open access
Research Article10.9734/jamps/2019/v21i430148
The objective of the present research work is to develop an ideal floating drug delivery system of nizatidine to increase the gastric residence time in stomach. To overcome the short half life and lower bioavailability of drug in tablet form we developed the drug in the form of e...
Open access
Research Article10.9734/jamps/2019/v21i430146
This study investigated therapeutic effect of ethanol extract of Anthocleista vogelii stem bark (EEAV) in the treatment of jaundice on paracetamol-induced hepatotoxicity in adult wistar rats. A total of 30 wistar rats weighing between 160-200 g were distributed into 6 groups comp...
Open access
Research Article10.9734/jamps/2019/v21i430145