The objective of this article is to develop cell differentiation agent (CDA) formulations to the rescue of cancer patients whose cancer stem cells (CSCs) have become a dominant issue such as metastatic, unresponsive and recurrent cancer patients. Although CSCs are only a small mi...
Open access
Research Article10.9734/jcti/2024/v14i2254
M.K. Mukarram Hussain, Sunil Kumar Agrawala, Sudam Sadangi, Snehasis Pradhan, Sangram Keshari Panda, Shyam Kumar Hariharan & Vikas K Sankar·Journal of Cancer and Tumor International·2024
Persistent Mullerian Duct Syndrome (PMDS) is a rare type of male pseudohermaphroditism. It is brought on by an insufficiency of anti-mullerian hormone (AMH) or a malfunction of its receptor (type II). Approximately 150 adult cases of PMDS have been documented overall, with the ma...
Open access
Research Article10.9734/jcti/2024/v14i2253
Mesenchymal Stem Cells (MSC) are a type of stem cell that is multipotent and originates from the mesoderm and ectoderm at an early stage of development and can differentiate into: 1. Ectodermal derivatives such as: neurons, keratocytes and keratinocytes; 2. Endodermal derivatives...
Open access
Research Article10.9734/jcti/2024/v14i2252
Anisha Nallasamy, Manju Rajput, Zahid Ahmad Wani, Maryam Khazir Dar, Aakanksha, Sheikh Hibban Fayaz, Subiksha S & Naveen H Simon·Journal of Cancer and Tumor International·2024
Cancer immunotherapy has transformed cancer treatment by harnessing the immune system to recognize and eliminate cancer cells. Recent years have witnessed significant advancements in this field, including the development of immune checkpoint inhibitors, chimeric antigen receptor...
Open access
Research Article10.9734/jcti/2024/v14i2251
The combination of adjuvant Abemaciclib with endocrine therapy (ET) has emerged as a significant advancement in the management of HR+, HER2-, node-positive, high-risk early breast cancer, as demonstrated by the findings of the MonarchE trial. This innovative treatment approach yi...
Open access
Research Article10.9734/jcti/2024/v14i2250
Aim: Records have been reported on the inflicting attributes of cancer in society and how early detection is necessary for preventive measure and as a proactive step. The use of Magnetic Resonance Imaging (MRI) has been proved as an effective and proficient diagnostic method for...
Open access
Research Article10.9734/jcti/2024/v14i1249
Anti-PD-1 and anti-PD-L1 are therapies that have shown success in cancer treatment. However, while treating cancer with PD-1/PD-L1 blockade is similar, the clinical response rate is still low in certain cancers at around 40%. Therefore, therapeutic strategies are needed to increa...
Open access
Research Article10.9734/jcti/2024/v14i1248
Quiescent cancer stem cells (QCSC) are non-proliferating cells that survive in the G0 phase and have low ki-67 expression and high p27 expression. QCSCs have the ability to evade most chemotherapy, and some subsequent treatments may result in a higher proportion of quiescent canc...
Open access
Research Article10.9734/jcti/2024/v14i1247
Adipose-derived stem cells (ASC) are cells from the core of fat tissue that secrete various cytokines, growth factors, proteins and extracellular vesicles that can be used in regenerative therapy, especially in the case of cancer. This ASC produces a secretome which is an exosome...
Open access
Research Article10.9734/jcti/2024/v14i1244
Rushin Patel, Mrunal Patel, Zalak Patel, Himanshu Kavani, Afoma Onyechi, Jessica Ohemeng-Dapaah, Dhruvkumar Gadhiya, Darshil Patel & Chieh Yang·Journal of Cancer and Tumor International·2024
Objective: The objective of this study is to thoroughly investigate the use of artificial intelligence (AI) and machine learning (ML) techniques for diagnosing and predicting prognosis in gastric cancer, utilizing the latest available data. Methods: Following the Preferred Report...
Open access
Research Article10.9734/jcti/2024/v14i1241