Solanum americanum, a medicinal plant traditionally used to treat inflammation, anemia, and kidney disorders, was evaluated for its antioxidant, anti-arthritic, anti-struvite, and anti-sickling properties. Methanolic extracts of S. americanum leaves (MESAL) were prepared and test...
Open access
Research Article10.9734/jpri/2025/v37i107749
Aim: To compare and assess the efficacy of preoperative submucosal injection of 8 mg dexamethasone versus 40 mg methylprednisolone for bilaterally symmetrical impacted mandibular third molar surgery. Materials and Methodology: The study was conducted on the subjects requiring sur...
Open access
Research Article10.9734/jpri/2025/v37i97746
Kamalesh D Mali, Kalyani Krishna vairagade, Abhay Himmat Sabale, Pankaj Raju Vibhute, Janhavi Sunil Gorane, Nikita Suresh Kumawat, Manish Bansilal Gagarani & Vivek Sudam Kumawat·Journal of Pharmaceutical Research International·2025
Lornoxicam, a potent nonsteroidal anti-inflammatory drug (NSAID), suffers from poor aqueous solubility, leading to limited dissolution and variable bioavailability. It is a nonsteroidal anti-inflammatory medication (NSAID) that is commonly recommended to treat rheumatoid arthriti...
Open access
Research Article10.9734/jpri/2025/v37i97747
Dementia is a progressive neurodegenerative disease that significantly affects patients, caregivers, and health systems worldwide. Collaborative care models (CCMs) have emerged as promising strategies that integrate multidisciplinary interventions to improve patient outcomes and...
Open access
Research Article10.9734/jpri/2025/v37i97744
This study focuses on the synthesis, molecular docking, and anticancer activity evaluation of a series of novel pyridine derivatives (Compounds 7a-7g). The compounds were synthesized through a series of chemical reactions and characterized using spectroscopic methods. In vitro an...
Open access
Research Article10.9734/jpri/2025/v37i97745
Introduction: Migraine is a chronic neurological disorder with recurrent headaches and aura, shaped by both environmental and genetic factors. In Saudi Arabia, rising prevalence contrasts with scarce genetic research. This study systematically reviews local evidence on migraine-r...
Open access
Research Article10.9734/jpri/2025/v37i97743
Sarabjot Singh-Sethi-Makkar, Parinita Aroori, Leela Sarmada Gaddamanugu, Siddharth Thokale, Krishna Moparthi, Kyaw Hein & Sanjana Palakodeti·Journal of Pharmaceutical Research International·2025
Background: Migraines are a common neurological disorder which are characterised by recurrent headaches accompanied by ‘auras’, nausea, vomiting and photophobia. Objective: This review summarises the role of Calcitonin gene-related peptide (CGRP) in migraine as a therapeutic and...
Open access
Research Article10.9734/jpri/2025/v37i97742
Chia (Salvia hispanica L.) is an emerging oilseed crop renowned for its rich nutritional profile and diverse health-promoting properties. Black chia seed oil (BCO) is particularly valued for its high content of omega-3 fatty acids and bioactive compounds, making it a promising fu...
Open access
Research Article10.9734/jpri/2025/v37i97740
Tapinanthus globiferus, a hemiparasitic mistletoe extensively used in African ethnomedicine, was evaluated for its redox-modulatory and cytotoxic properties using Drosophila melanogaster under non-stressed physiological conditions. Methanolic crude extract and solvent-partitioned...
Open access
Research Article10.9734/jpri/2025/v37i97739
Aims: The propagation of light in vacuo has generally been assumed to be isotropic; i.e., its recessional velocity is assumed to be identical with its return speed back to the observer. This article presents a novel conceptual approach to this fundamental yet unresolved issue in...
Open access
Research Article10.9734/iaarj/2025/v7i1118