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Research Article Open access CC BY 4.0

A Case Report on Sagliker Syndrome- A 3 Sequelae of Chronic Kidney Disease

Debdita Banerjee, Sudeshna Bagchi, Arunit Chatterjee, Swagata Gayen

Journal of Advances in Medicine and Medical Research · pp. 235–240 · Published 17 May 2025

10.9734/jammr/2025/v37i55833

Abstract

Sagliker syndrome was first recognized in medical literature in the year 2004, taking into account the bizarre craniofacial malformities and systemic manifestations in patients with uncontrolled Secondary Hyperparathyroidism (SHPT) arising from Chronic Renal Failure (CRF). This syndrome describes the “uglifying” maxillofacial deformations and skeletal changes observed in subjects who have been under prolonged haemodialysis for end stage renal disease. Till date it remains an elusive entity and patients often go undiagnosed which significantly diminishes their quality of life and treatment outcomes. This case report aims at presenting a rare manifestation of the syndrome in a 22-year-old female patient, concentrating on a variety of clinical radiographical and biochemical findings.

Chronic renal failure sagliker syndrome secondary hyper parathyroidism “uglifying” craniofacial malformities

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